Nomigrain 5mg Torrent Treatment Treatment Migraine (5 blisters x 20 tablets)

Dosage form Box of 5 blisters x 20 tablets
Specifications Flunarizine

Ingredient

Composition information	Content
Flunarizine	5mg

Uses

Indications

Nomigrain drugs are indicated in the following cases:

Preventive treatment of migraine in case other treatments is not effective or less tolerant.

Pharmacy

nomigrain is said to inhibit the calcium line entering cells in cases of calcium entering the cell too much and causing damage to cells due to calcium overload. Hence the drug is classified as an overload inhibitor.

Nomigrain also inhibits smooth muscle contraction due to the entry of extracellular calcium. Nomigrain reduces the hardness of red blood cells due to calcium overload and also reduces the effect of deficiency of oxygen in brain cells. Normigrain also shows the effect of inhibiting vestibular as well as antihistamine and anti -convulsions.

pharmacokinetics

Nomigrain's peak plasma concentration appears 2 to 4 hours after drinking. Nomigrain is widely distributed into the tissue. It is widely metabolized by N - Dealyl oxidation, aromatic and glucuronic complex hydroxy and eliminated in bile. Nomigrain's ending time is about 18 days in healthy people.

Before taking Nomigrain 5mg Torrent Treatment Treatment Migraine (5 blisters x 20 tablets)

How to use

Oral drugs.

Dosage

adults 65 years old)

Use 5mg/day, drink in the evening, maintain for 4 to 8 weeks.

During treatment, if the symptoms of depression, foreign tower or other serious adverse events appear, it is necessary to stop taking the drug.

If after 8 weeks of treatment there is no improvement, the patient is considered not responded to treatment and should stop taking the drug.

Treatment time does not exceed 6 months.

Recommendation is only for patients

If the patient's clinical manifestation shows that the response is incomplete, it may increase the dose to 10mg/day but need to consider in the patient's tolerance ability.

Children

12 -year -old children, especially in the case of unexplied migraine:

5mg/day, drink in the evening. Treatment period must not exceed 6 months.

Children

There is no full evidence of the effectiveness and safety of flunarizin on this object. It is not recommended to use flunarizin for children under 12 years old.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? In some cases of acute overdose (up to 600mg for use) have been reported and observed symptoms include the effects on the central nervous system such as drowsiness, confusion and the effects on the cardiovascular system such as tachycardia. Acute dose treatment includes activated carbon, vomiting or gastric lavage and supportive treatment. Unknown antidote specific.

What to do when forgetting a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Nomigrain, you may experience unwanted effects (ADR).

Nomigrain is well tolerated. The adverse effect is mainly sedative in about 7% of patients. Other adverse effects appear less than 1% of patients who have been reported: headache, stomach pain, nausea, insomnia, dry mouth and rash.

Adultery effects on the outskirts are attributed to Normigrain, which has been reported in rare schools and only encountered in the elderly. Sometimes Normigrain increases slightly, usually temporary.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Nomigrain drugs contraindicated in the following cases:

Hypersensitivity to flunarizin or any excipients of the drug.

Symptoms of Parkinson's disease before treatment.

History of foreign symptoms.

depression or a history of recurrent depression syndrome.

Precautions when using

due to sedative or drowsiness occurs in some patients while using Nomigrain, patients should be cautious for activities that need apple or agile and accurate response such as operating machines or driving, until response to the defined drug. Flunarize is metabolized in the liver, so be careful when using Flunarizine in patients with liver failure.

Do not use the recommended overdose. It is necessary to monitor patients regularly, periodically, especially during the maintenance treatment period to early detect expressions of foreign tapes, depression and stop treatment promptly.

Some fatigue cases with increasing severity have been recorded when using flunarizin. If this condition occurs, it is necessary to stop treating with flunarizin.

The ability to drive and operate machinery

Precautions when taking the drug.

Pregnancy

There is no complete and well -verified research on Nomigrain used during pregnancy. Therefore, the drug should only be used in these cases, when it is a mandatory indication.

Breastfeeding period

There is no adequate and well -verified research on Nomigrain used during breastfeeding. Therefore, the drug should only be used in these cases, when it is a mandatory indication.

Drug interaction

evidence in patients with epilepsy shows that flunarizine does not affect pharmacokinetics of phenytoin, carbamazepine and valproic acid, it reduces the plasma concentration of mephenytoin. Nomigrain's stable concentration is reduced when used simultaneously with two or more anticonvulsants. A lot of drowsiness can be used when using alcohol, sleeping medicine or sedative at the same time as nomigrain.

Storage

Store at temperatures below 30 ° C.

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Disclaimer

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