Nootropil tablets 800mg GSK treat mental syndrome (3 blisters x 15 tablets)

Dosage form Box of 3 blisters x 15 tablets
Specifications Piracetam

Ingredient

Composition information	Content
Piracetam	800mg

Uses

indications

Nootropil is indicated in the following cases:

Adults

Treatment of symptoms of mental-formation syndrome with improved characteristics by treatment such as memory loss , attention disorders and lack of motivation. God.

Treatment of difficult to read, combined with appropriate measures such as speaking therapy. Piracetam is physically connected to the polar head of phospholipids in the cell membrane model according to the dose dependent, creating the restoration of the thin plastic structure of the cell membrane characterized by the formation of flexible phospholipids.

This can lead to improved cell membrane stability, allowing membrane proteins and piercing proteins to maintain or restore three -dimensional or folded structure to perform the function of the strain. Piracetam works on nerves and blood vessels.

Pharmacokinetics

absorption

Piracetam is absorbed quickly and almost completely. The peak concentration of plasma is achieved within 1.5 hours after use.

Distribution

Piracetam's distribution voltage is 0.7 l/kg. Piracetam passes through brain blood and placental fences and diffuses through the membranes used in the kidneys.

Metabolism

Piracetam does not metabolize in the human body. This is shown by the half -life of the drug in a dawn patient and the very high concentration of drugs found in the urine.

Elimination

Piracetam is excreted almost entirely in urine and the dose of excretion through urine does not depend on the dose. Selling waste time in plasma is 5.0 hours.

Before taking Nootropil tablets 800mg GSK treat mental syndrome (3 blisters x 15 tablets)

How to use

piracetam can be taken or not with food. Should take film tablets with liquid.

Dosage

adults

Symptomatic treatment of mental syndrome - entity

Common dose is 2.4 g - 4.8 g/day (3 to 6 tablets/day), divided equally 2-3 times/day.

Treatment of muscle vibration is derived from the cerebral cortex:

Starting daily dose is 7.2 g, then increasing 4.8 g every 3-4 days can reach the maximum dose of the day of 20 g, divided into 2-3 times. Treatment with other muscle vibration drugs should be maintained with the dose.

Depending on the clinical benefits achieved, the dose of these drugs should be reduced, if possible. The dose must be determined by the patient by trying treatment. Once you have started, it is advisable to continue treating with piracetam as long as the cerebral disease still exists.

In patients with an acute attack, the disease can progress accidentally after a period of time and so every 6 months should try reducing the dose or stopping treatment.

Should reduce 1.2 g of Piracetam every 2 days (every 3 or 4 days in the event of a Lance-adams syndrome to prevent the possibility of sudden recurrence or convulsions due to sudden suspension).

Dizziness treatment:

Daily dose is recommended in the range of 2.4 g to 4.8 g divided into 2-3 times.

Treatment of difficult to read

For children 8 years old and young people dose recommend 2 tablets 800 mg in the morning and evening

Patients with renal impairment: Contraindicated on patients with severe renal impairment, dose adjustment with the remaining objects based on creatinine clearance coefficient.

Elderly patients: adjusting the dose in patients with kidney function damage.

Patients with liver failure: Do not adjust the dose in patients with only liver failure, need to adjust the dose if both liver failure and kidney failure.

The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when overdose? The highest overdose is to take Piracetam 75 g, the appearance of bloody diarrhea with abdominal stomach, most likely related to the very high sorbitol dose in the ingredients of the drug.

Handling

Cases of significant, acute overdose, may make the stomach empty by using vomiting. There is no specific antidote. Overdose treatment mainly treat symptoms and may include hemorrhage.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Nootropyl, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Weight gain;

restlessness;

hyperactivity.

Uncommon, 1/1000

depression ;

weakness ; drowsy.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Nootropil contraindicated in the following cases:

Hypersensitivity to piracetam, other derivatives of pyrrolidone or any excipients of the drug.

End -stage kidney disease (renal creatinine clearance below 20 m/min).

Cerebral hemorrhage: Piracetam should not be used for patients with dancing Huntington (Huntington's Chorea).

Caution when using

The impact on platelet gathering due to the impact of piracetam on platelet aggregation, should be cautious when used for patients with severe bleeding, patients at risk of bleeding such as gastrointestinal ulcer , patients with potential hematuria disorders, patients with a history of brain vasoconstriction due to hemorrhage, patients with anti -surgical patients or patients with anti -surgery Platelets include low -dose aspirin.

Piracetam kidney failure is eliminated through the kidneys, so be careful in the case of renal failure.

When long -term treatment in the elderly, regular evaluation of creatinine is needed to adjust the appropriate dose when needed.

Should avoid sudden treatment because it can cause muscle seizures or compromise all seizures in some patients with muscle -shock.

With indications in sickle blood cells, a dose of less than 160 mg/kg/day or infrequent drug use can lead to recurrence of acute attacks.

The drug contains about 2 mmol (or about 46 mg) sodium for every 24 g of piracetam. It is necessary to consider when used for patients who are using diet to control the amount of sodium.

The ability to drive and operate machinery

With adverse effects recorded when taking the drug, the drug may affect driving and operating machinery, and this should be noted.

Pregnancy

should not use piracetam during pregnancy unless it is necessary, when the benefits are superior to the risk and clinical status of pregnant women, they require piracetam treatment.

breastfeeding period

Do not use piracetam while breastfeeding or no breastfeeding during piracetam treatment. The benefits of breastfeeding should be taken into account and the benefits of treatment for mothers when deciding not to breastfeed or do not use Piracetam.

Drug interaction

The drug interaction is likely to lead to piracetam pharmacokinetic changes that are expected to be low because about 90% of Piracetam's spots are discharged in unchanged urine.

Homone thyroid: Causes confusion, easy to stimulate and then sleep disorder has been recorded when taking this medication at the same time with the extract of the thyroid gland (T3 + T4). Acenocoumarol: Compared to the effect of acenocoumarol used alone, the addition of Piracetam significantly reduces platelet aggregation and viscosity of whole blood and plasma.

Anti -epileptic drugs: Piracetam use for 4 weeks with daily doses of 20 g does not change the peak concentration and bottom concentration of serum of anti -epileptic drugs (carbamazepine, phenyloin , phenobarbitone, valproate).

Alcohol: Drinking alcohol at the same time does not affect the concentration of piracetam in serum.

Storage

Store drugs in a dry place, no more than 30 oC, avoid direct light.

To be out of reach of children.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.