Odiron United tablet prevention and treatment of anemia (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Iron, folic acid, pyridoxine hydrochloride, cyanocobalamin

Ingredient

Composition informationContent
Iron60mg
Folic acid600mcg
Pyridoxine hydrochloride20mg
Cyanocobalamin25mcg

Uses

Indications

Odiron drug prescribed treatment in the following cases:

  • Prevention and treatment of iron deficiency anemia in pregnant and lactating women. .v.v.

    Essential iron for hematoma, transportation and oxygen reserves and is an important co-factor for cell activity.

    Folic Acid is essential for the prevention of neural tube defects (NTDS) in newborns characterized by neural tube defects including vertebral crackers that can lead to many physical defects (such as paralysis and hydrocephalus). Providing adequate folats helps prevent obstetric complications, including non -bleeding, bleeding, lightweight child and defects for the fetus. Folat deficiency is the main concern during pregnancy because during this period, the effect of folat absorption is significantly reduced and the speed of folat excretion in urine increases.

    Vitamin B6 and B12 plays a role in the synthesis of hemoglobin and red blood cells. These nutrients also promote energy metabolism and can help reduce anorexia, myastal, nausea and vomiting.

    Folic acid, vitamin B6 and B12 impact catalytic force in homocysteine ​​metabolism to prevent increased bloodsteine ​​homocysteine.

    pharmacokinetics

    No report.

    • Before taking Odiron United tablet prevention and treatment of anemia (3 blisters x 10 tablets)

    How to use

    oral medication.

    Dosage

    Take a film tablet every day or as instructed by a physician.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

    What to do when overdose?

    Early manifestations of acute iron poisoning include diarrhea, sometimes diarrhea, fever, vomiting, stomach cramping, vomiting, sometimes vomiting blood. The later symptoms include lips, nails and palms of blue, drowsy, pale, moist skin, sometimes twitching, breathing fast and shallow, weak, abnormal fatigue, fast and weak heartbeat.

    Acute iron overdose should be treated immediately after drinking. In case of overdose may cause vomiting with ipecac syrup or stomach with sodium bicarbonate depending on the patient's condition. In case of severe poisoning, Deferoxamine is an antidote that can be used intravenously or intramuscularly. Disclosure in the case of renal failure. Water compensation and electrolyte imbalance if any, lifting blood pressure with dopamine if necessary.

    In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

    What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

    Side Effects

    When using Odiron often has unwanted effects (ADR) such as:

    iron

    Side effects on the digestive system are often related to the amount of elemental iron used rather than the preparation. Other side effects may include diarrhea or constipation. Can reduce side effects by taking medication during or after eating or by starting treatment at low doses and increasing the dose gradually. Can change teeth temporarily. Can go black feces.

    pyridoxine

    pyridoxine is usually not toxic. Using pyridoxine lasted at a dose of 10mg/day is said to be safe but using pyridoxine for a long time at a dose of 200mg or more daily can cause neurological disease.

    Central nerve: headache, convulsions, drowsiness.

    Endocrine and metabolism: Acid infection, folic acid decreased.

    Digestive: Nausea and vomiting.

    liver: AST increases.

    Neuros - Muscle: Taking a dose of 200mg/day and long (over 2 months) can cause severe peripheral nerve inflammation, progressing from a unsteady gait and numbness to a numbness and clumsy hands. This condition can recover when stopping the drug, although there are still many sequelae.

    Other: allergic reactions, burning sensation, itching can occur.

    cyanocobalamin

    Systemic: Anaphylaxis, fever, headache, dizziness, bronchospasm, mouth angio - Most.

    Skin exterior: Fish egg -like reactions, urticaria, erythema, itching.

    Digestive: nausea.

    Cardiovascular: Secondary arrhythmia due to hypokalemia at the beginning of treatment.

    Instructions on how to handle ADR

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    Odiron drugs are contraindicated in the following cases:

  • Sensitive to any component in the formula.
  • There is malignant or suspected tumor.
    • iron: Fairy iron pigmentation, stomach ulcers, bowelitis or colitis causes ulcer.

    Precautions when using

    iron

    Do not use iron to treat hemolytic anemia except for iron deficiency.

    Do not use iron injected with oral iron to avoid excess iron.

    Do not use iron for patients with blood transfusions many times, due to a significant amount of iron in the hemoglobin of red blood cells.

    cyanocobalamin

    For malignant roof shortage, there should be a sufficient dosage and check the blood formula periodically every 3 months within the first 18 months until stable, then periodically check each year. Using cyanocobalamin can make the diagnosis inaccurate.

    The ability to drive and operate machinery

    No relevant information.

    Pregnancy

    pyridoxine

    Data on the safety of pyridoxine used for treatment dose during pregnancy has not recorded any harmful effects on the fetus. However, be careful when prescribing pyridoxine for pregnant women.

    cyanocobalamin

    Do not use cyanocobalamin to treat huge red blood cell anemia during pregnancy because this condition is due to folat deficiency.

    Breastfeeding period

    pyridoxine

    Data on the safety of pyridoxine used for treatment dose during breastfeeding has not recorded any harmful effects on young children.

    Medicinal interaction

    iron

    Use at the same time with oral antacids can reduce iron absorption.

    When taken at the same time iron salt and tetracycline because the absorption of both substances decreases.

    Response to iron may be slowed down when treated at the same time as chloramphenicol.

    The iron salts are also recorded reducing absorption and thus reducing the bioavailability and clinical effects of Levodopa with Carbidopa, Methyldopa, Penicillamine, and some quinolones (Ciprofloxacin, Norloxacin, ofloxacin). Do not use oral iron preparations at the same time or within 2 hours after using these drugs.

    folic acid

    Folic acid may increase phenytoin metabolism, resulting in a decrease in serum phenytoin concentration.

    Use chloramphenicol and folic acid in patients with folate deficiencies that can cause antagonism to respond to folic acid.

    pyridoxine

    Pyridoxine HCl can reduce the effect of Levodopa, the drug is used in the treatment of Parkinson's disease.

    cyanocobalamin

    Absorbing vitamin B12 from the gastrointestinal tract may be reduced when used simultaneously with neomycin, aminosalicylic acid, H2 and Colchicin receptor anti -receptors.

    Serum concentration may be reduced when used simultaneously with oral contraceptives. Chloramphenicol used on the gastrointestinal tract may reduce the effect of vitamin B12 in anemia.

    The treatment effect of vitamin B12 can be reduced when used simultaneously with omeprazol.

    Storage

    Store in a dry place, avoid light, temperature not exceeding 30 ° C.

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