Ointment Ointment Glenmark ointments treated skin infections (5g)

Dosage form Tube
Specifications Mupirocin

Ingredient

Composition information	Content
Mupirocin	2%

Uses

indications

Supirocin is indicated in the following cases:

Treatment on the spot of primary and secondary bacterial infections caused by sensitive bacteria such as exhaust, secondary infection wounds, burns, cellular inflammation, chronic leg ulcers, intravenous ulcer ...

mupirocin (pseudomonic acid; pseudomonic acid A) is an antibiotic produced by submerged fermentation pseudomonas fluorescens and has a different structure from other antibiotics. Other substances produced by Pseudomonas Fluorescens such as Pseudomonic Acid B, C and D have also been surveyed on antibacterial activity but Mupirocin has the most powerful antibacterial activity.

Much special mechanism of mupirocin, unlike other antibiotics, is a specific and reversible cohesion with the bacterial enzyme enzyme synthetase of bacteria leading to protein synthesis and RNA synthesis. Thanks to this mechanism of action, the speed of staphylococcus aureus in mupirocin in in vitro studies is low, and has no cross -resistance to other skin -used antibiotics.

mupirocin works against staphylococcus aureus strains of multi -resistance and negative staphylococcus aureus, including resistant strains with penicillin, methicillin, neomycin, erythromycin, fusidic acid, lincomycin, chloramphenicol, tetracyclin and gentamicin.

Dynamic pharmacokinetics

The bioavailability of mupirocin used on the spot is very low (0.24%). The permeability of mupirocin increases when the bandage is closed or applied to the damaged skin. 72 hours after taking the radioactive mark, there is a radioactive activity measured in the epidermis of these patients.

mupirocin is slowly metabolized in the skin into an inactive metabolic, monic acid. Only 2.7% Mupirocin is metabolized after 48 hours in human skin homogeneity. Only a very small amount of drugs are absorbed and metabolized, the main emissions are through the kidney (accounting for 56% to 90% of the total deduction).

Before taking Ointment Ointment Glenmark ointments treated skin infections (5g)

How to use

ointment topical skin.

Dosage

Adults

The common dose is applying a thin layer of Supirocin ointment to the damaged areas 2-3 times daily, from 5 to 10 days for patients with primary and secondary skin infections. Can apply the medication with gauze if desired. Only use treatment for wounds with a length below or equal to 10cm or with an area below or equal to 100cm2. Patients do not see the effect after 3-5 days of treatment must be re -examined.

Patients with severe infections may need longer treatment time, and if there is a systemic infection, body antibiotics must be used.

Children

According to the existing clinical data, mupirocin ointment is safe and effective when applied to skin for children from 2 months to 16 years old. Safe and effective for children under 2 months of age has not been determined.

For patients with impetigo, apply a small amount of mupirocin to the infected area 3 times daily. Can apply the medication with gauze if desired. Patients do not see the effect after 3-5 days of treatment must be re -examined.

How to apply medicine for children is similar to adults but it is best to use less medicine and the distance between the application longer.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? There is no experience for mupirocin ointment. No case of overdose of mupirocin ointment has been reported. Because mupirocin is very little absorbent, overdose of the drug is very rare.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Supirocin , you may experience unwanted effects (ADR).

Common, ADR> 1/100

In place: burning sensation, needle or pain, itching

Uncommon, rare, ADR

In place and the whole body: rash, nausea, erythema, dry skin, sensitive skin, swelling, contact dermatitis , and increased fluid.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Supirocin contraindicated in cases where patients with a knowledgeable or suspected hypersensitivity to mupirocin or any ingredients of the drug.

Be cautious when used

Supirocin ointment contains polylethylene glycol so it is not used for torn skin or mucous membranes, expanded wounds and burns. Because polyethylene glycol can be absorbed, then excreted through the kidney.

Similar to other polyethylene glycol ointments, do not use Supirocin for cases that can absorb large amounts of polyethylene glycol, especially when patients with moderate or severe renal failure.

Do not use eye, mouth, or in the vagina.

drugs used outside

Avoid applying large amounts of drugs and on the area too large. The skin is damaged, applied for a long time, and the topical bandage.

The ability to drive and operate machinery

no side effects on the ability to drive or operate the machine.

Pregnancy

Because animal studies do not always predict the response on humans, should only be used for pregnant women when they are really necessary.

Breastfeeding period

It is not known whether the drug is excreted through breast milk. Because many drugs excreted through breast milk, should be cautious when using mupirocin for breastfeeding women.

Medicinal interaction

The effect of simultaneous use of mupirocin ointment and body or other drugs that have not been studied much. However, because Mupirocin is very little absorbed through the skin, interacting with drugs with systemic drugs is not likely to occur.

Storage

Store less than 30 ° C, not to freeze.

Other drugs

Disclaimer

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