Olesom Gracure Sires treat acute and chronic respiratory diseases, bronchitis (100ml)

Dosage form Bottle x 100ml
Specifications Ambroxol

Ingredient

Composition information	Content
Ambroxol	30mg

Uses

Indications

Olesom drugs are indicated in the following cases:

Acute and chronic respiratory obstructions such as bronchial asthma and bronchitis, bronchiectasis due to the production of too much mucus and sputum. Increase the dissolution of mucus in nasopharyngitis.

Pharmacokic of

Treatment group: Mucus, mucus destruction.

ATC code: R05C B06.

Ambroxol is a metabolic substance of bromhexin, which has the same effect and uses similar to bromhexin. Ambroxol has the effect of making sputum more liquid, less slightly so it is easy to get out, so the drug has the effect of long sputum. A few documents stated that Ambroxol improves symptoms and reduces the number of exacerbations in severe chronic obstructive pulmonary disease. Recent research results show that ambroxol is anti -inflammatory properties and has the activity of antioxidants. In addition, Ambroxol also has local anesthetic effect through sodium channel blockers in the cell membrane. Ambroxol can stimulate synthesis and excretion of alveolar activity. The drug has been considered an alveolar activity. However, the drug is not effective when used for mothers to prevent respiratory failure syndrome in newborns, but the drug has a modest effect when treating early for children. Ambroxol also has the effect of secreting uric acid through pepper, this effect depends on the dose. The minimum dosage effectively reduces plasma uric acid by 250 - 500 mg/day divided into 2 times. High doses up to 1g still good tolerance.

pharmacokinetics

Ambroxol quickly absorbed after oral, fast diffuse from blood to tissue with the highest concentration of drugs in the lungs. Birth is about 70%. The maximum concentration in plasma is achieved within 0.5 - 3 hours after taking the drug. With the dose of treatment, the drug is linked to plasma protein approximately 90%. Half life in plasma from 7 - 12 hours. Ambroxol is metabolized mainly in the liver. The drug excreted through the kidney is about 83%.

Before taking Olesom Gracure Sires treat acute and chronic respiratory diseases, bronchitis (100ml)

How to use

Take oral, should take medicine with plenty of water after eating. Drinking plenty of water during treatment will help increase the dissolved effect of mucus of ambroxol.

Dosage

for adults and children over 12 years old, recommended dose for the first 2-3 days of treatment is 5ml x 3 times/day, then use 5ml x 2 times/day or 2.5ml x 3 times/day on the next day.

For children from 5 to 12 years of age, the usual dose is 2.5ml x 2-3 times/day.

Children from 2 - 5 years old are 1.25ml x 3 times/day.

Children under 2 years old: 1.25ml x 2 times/day.

When suffering from severe kidney failure, the dose should be reduced or increased the distance between drug use.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

When using the drug overdose, the first thing to do is vomit and add drinking water (milk or tea). If used overdose within 1-2 hours earlier, gastric wash should be carried out. Activated carbon can be used and treated symptoms after detoxification. Need to continue monitoring the circulatory system.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using olesom drugs, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive: heartburn, indigestion, sometimes nausea, vomiting.

Uncommon, 1/1000

allergies, mainly rash.

Rare, ADR

Acute, heavy anaphylactic reaction, but is not sure to be related to ambroxol, dry mouth, and increased transaminase. There have been several reports of severe skin damage such as Stevens-Johnson syndrome and poisoned epidermal necrosis related to the use of sputum drugs such as Ambroxol Hydrochloride. Most of these cases are explained by a patient who is seriously ill and/or because of a combination of drugs.

Moreover, in the early stages of Stevens - Johnson syndrome or poisoned epidermal necrosis, patients may have notice symptoms that are not typical like influenza such as fever, human pain, rhinitis, them and sore throat. The misconception of the notice symptoms is not typical like this influenza, causing the patient to be treated with cough and flu medicine. Therefore, if you see new skin lesions or mucosa, you should consult your doctor immediately and stop using Ambroxol Hydrochloride.

Note: If you see any changes on the skin or mucosa, you should stop taking the medication immediately and consult your doctor.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Siro olesom contraindicated in the following cases:

Hypersensitivity to Ambroxol, Bromhexin or any other ingredient of the drug.

Precautions when using

need to take into account the possibility of sensitive reaction when using the drug. There have been several reports of severe skin lesions such as Stevens-Johnson syndrome and infected necrosis related to the use of sputum drugs such as Ambroxol Hydrochloride. Most of these cases are explained by a patient who is seriously ill and/or because of a combination of drugs. Moreover, in the early stages of the Stevens -Johnson syndrome or the epidemic necrosis is poisoned, the patient may have notice symptoms that are not typical like the flu, such as fever, human pain, rhinitis, cough and sore throat. The misconceptions of the notice symptoms are not typical like this flu, which will make patients treat with their drugs and flu. Therefore, if you see new skin lesions or mucosa, you should consult your doctor immediately and stop using Ambroxol Hydrochloride.

Note: If you see any changes on the skin or mucosa, you should stop taking the medication immediately and consult your doctor.

Need to be particularly cautious when used for patients with trachea disorders or patients with too much phlegm.

Severe renal failure: Ambroxol's waste time increases in patients with severe renal impairment, so it may be necessary to reduce the dose or reduce the frequency of drug use. ASPARTame excipients 60 mg/bottle of 100ml (equivalent to 0.6 mg/ml). Aspartame is a source of phenylalanin. It can be harmful to people with urinary phenylketon (PKU), a rare genetic disorder that causes phenylalanin accumulation due to the body's not removed. Drugs containing Tartrazine Supra can cause allergic reactions.

The ability to drive and operate machinery

There is no evidence of the effect of the drug on the ability to drive and operate machinery.

Using drugs for pregnant and lactating women

Pre -clinical data: So far has not been observed to see the monster effects in preclinical studies.

On humans: Do not use for pregnant and lactating women.

Medicinal interaction

Use ambroxol with antibiotics (amoxicillin, cefuroxim, erythromycin, Doxycyclin) as antibiotic talent in lung parenchyma.

Do not combine ambroxol with a anti -cough drug (such as Codein) or a sputum drying (e.g. atropin): unreasonable coordination.

Cavalry:

Due to the absence of studies on the correlation of the drug, not mixing this drug with other drugs.

Storage

Store drugs in a cool dry place, temperatures below 30 ° C, avoid light.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.