Oliveirim 10mg tablets Davipharm prevent migraine, dizziness (6 blisters x 10 tablets)

Dosage form Box of 6 blisters x 10 tablets
Specifications Flunarizine

Ingredient

Composition information	Content
Flunarizine	10mg

Uses

indications

Oliveirim 10 mg is indicated in the following cases:

Preventy migraine . Histamine, sedation and calcium channel blockers.

Flunarizin Hydrochlorid is used to prevent migraine, vestibular disorders and anti -face, cerebrovascular disorders and peripheral blood vessels. It has also been used as an anti -epileptic measure in patients who do not respond to the standard treatment regimen.

pharmacokinetics

absorption: The drug is well absorbed through the intestinal tract, reaching the peak concentration within 2-4 hours and reaching the status of the status at 5-6 weeks.

Distribution: Large distribution volume of 78 l/ kg in healthy people and 207 l/ kg in patients with epilepsy due to wide distribution in blood vessel tissues. 99% Flunarizin is connected to plasma proteins, passing the brain fence quickly and reaching a concentration about 10 times higher than the plasma concentration.

Metabolism: Flunarizin metabolizes in the liver into at least 15 metabolites, mainly through CYP2D6.

Elimination: Flunarizin and substances are excreted in bile ducts. Within 24 to 48 hours after taking the drug, about 3-5% of the dose is excreted in the form of intact drugs and metabolic substances, less than 1% are excreted intact in the urine. The half -life is at the end of about 18 days.

Before taking Oliveirim 10mg tablets Davipharm prevent migraine, dizziness (6 blisters x 10 tablets)

How to use

Take oral and take medicine in the evening.

Dosage

Preventive Preventive Migraine

Starting dose:

Patients under 65 years old: 10mg/day. If after 2 months of taking the drug without a significant improvement, the patient is considered not to respond and should stop treatment.

Maintenance dose: If the patient responds well and requires maintenance treatment, the dose should be reduced to 5 mg/ day and 2 days off. If treatment is maintained successfully and well tolerated, it may stop treating for 6 months and only start treatment if recurrent.

Dizziness, vestibular disorders, cerebrovascular disorders and peripheral blood vessels

The daily dose is similar for migraine, but the starting treatment only lasts until the symptoms are controlled, usually less than 2 months.

If there is no significant improvement after 1 month for chronic dizziness, 2 months for dizziness, the patient is considered as not responding and should stop treatment.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

How to handle: There is no specific antidote. Within 1 hour after overdose, the stomach should be lavely. Can use activated carbon if appropriate.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Oliveirim 10 mg, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Nervous system: Sleep and/or fatigue

Other: weight gain and/or increase the appetite

less common, 1/1000

Nervous system: Drowsiness, anxiety

The digestive system: heat in the breastbone, nausea, stomach pain

Skin and subcutaneous tissue: other rash

Dioto pain, increased milk secretion, dry mouth

Some of the following serious unwanted effects occur.

Depression , especially in danger of occurring in female patients with a history of depression. Therefore should be used carefully in these patients.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Oliveirim 10mg drug is contraindicated in cases where patients have a history of depression or are having symptoms of depression, patients with a history of Parkinson or other permanent disorders.

Be cautious when used

Use cautiously in older patients because it can increase the symptoms of foreign tapes, depression and the development of Parkinson's syndrome.

In some rare cases: fatigue may increase during treatment with flunarizin, this case should stop treatment. Do not exceed the decisive dose. Patients must be regularly examined, especially during the maintenance treatment stage, so that they can detect foreign or depression symptoms early and stop treatment. If in the maintenance phase that does not work effectively, the drug should be stopped.

The ability to drive and operate machinery

The drug can cause drowsiness, especially at the beginning of treatment. If cautious in activities such as driving or operating dangerous machines.

Pregnancy

There has been no study to confirm the safety of flunarizin when used in pregnant women. Therefore, this drug is not used in pregnant women, unless the benefits are superior to the risk of the fetus.

breastfeeding period

No report shows whether flunarizin is distributed in human milk or not, therefore, it is not recommended to use flunarizin in nursing women.

Interactive drug

alcohol, sedative, sleeping pills when shared flunarizin increases drowsiness.

Flunarizin is not contraindicated in patients taking beta blockers.

Storage

Store in a dry place, avoid light and humidity, temperatures below 30 ºC.

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