Olopat OD 0.2% Ajanta eye drops treat itchy eye in combination with allergic conjunctivitis (3ml)

Dosage form Bottle x 3ml
Specifications Olopatadine hydrochloride

Ingredient

Composition information	Content
Olopatadine hydrochloride	2mg/ml

Uses

indications

Olopat Od Ajanta 3ml drug is indicated in the following case:

Treatment of itchy eye in combination with allergic conjunctivitis.

Pharmacokology

olopatadin is a histamine release inhibitor from cell nourishment and is a relatively selective antagonist H1 H1, inhibiting the 1 -in allergic reaction 1 in vivo and in vitro including the inhibition of histamine effect on composition epithelium cells. Olopatadin does not have an impact on the alpha-adrenergic receptor, dopamine, and Muscarinic tube receptor 1 and 2.

Dynamic pharmacokinetics

Absorption: After the eyes are small, olopatadin is absorbed the whole body very little. Two studies conducted on healthy prayers (a total of 24 patients) using 0.15% olopatadin eye solution every 12 hours in 12 weeks showing that the serum olopatadine concentration is generally lower than the quantitative limit (

Elimination: Serum half -life is approximately 3 hours and the drug is excreted mainly through the kidneys. About 60 - 70% of the absorbing drugs are excreted in urine in the form of unchanged. The two main metabolites are mono-Desmethyl and N-Oxyd are eliminated in urine with low concentrations.

Before taking Olopat OD 0.2% Ajanta eye drops treat itchy eye in combination with allergic conjunctivitis (3ml)

How to use

Use small eyes.

Dosage

1 drops of 1 drop in each eye is sick once daily.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when using overdose? Olopatadine has low toxicity for experimental animals. Accidentally taking the vial in the abdomen, the olopatadin content absorbed into the body is only 5 mg. With the assumption of 100%absorbed drug, drinking 1 bottle of 5 ml of olopatadin 1 mg/ml is equivalent to a dose of 0.5 mg/kg for a child weighing 10 kg.

In case of overdose, patients need to be supervised and properly treated.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Olopat Od Ajanta 3ml, you may experience unwanted effects (ADR):

Very common, ADR> 1/10

Throat: Cold and sore throat syndrome.

Common, 1/100

Eyes: blurred vision, hot or eye aches, inflammation, dry eyes, sensation of strange things, congestion, pain, itchy eye, corneal inflammation, eyelid edema, pain, itchy eye.

Body: weakness, back pain, flu syndrome, headache, cough, infection, nausea, rhinitis, sinusitis, taste disorders.

Instructions on how to handle ADR

Notify the doctor the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Olopat Od Ajanta 3ml drug is contraindicated in the following cases:

Hypersensitivity to olopatadin or any ingredients of the drug.

Be cautious when using

drugs only used on the spot, not to be taken or injected.

Use the drug within a month after opening.

Patients should not wear contact lenses when reding. The drug is not used for treatment when irritated by contact lenses. Benzalkonium chlorid preservatives can be absorbed by soft contact lenses and no red eyes need to be advised to wait at least 10 minutes after the drug before wearing glasses.

Use drugs for children: Safety and effectiveness when taking this drug for children under 3 years of age has not been established.

Take medicine for the elderly: Safety and effectiveness between the elderly group and the younger group has no difference.

The ability to drive and operate machinery

Similar to any other eye medication may occur from temporary vision or visual disorders as soon as the drug is small. When the above situation occurs, the patient needs to wait until it is clear before driving or operating machines.

Pregnancy

Classification C during pregnancy, there is not enough evidence to have good control research in pregnant women. Only use Olopat Od Ajanta 3ml when the benefit gives the mother with the risk of the embryo or fetus.

breastfeeding period

Precautions when used with breastfeeding mothers.

Drug interaction

There has been no clinical interaction studies of olopatadin.

In vitro studies show that olopatadin does not inhibit metabolic reactions, related to iszyme 1A2, 2C8, 2C9, 2C19, 2D6, 2E1 and 3A4 of Cytochrome P450. These results show that olopatadin does not seem to affect the metabolism of other drugs when used simultaneously.

Storage

Store the vials is closed below 30 ° C in the dark.

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