OPV Re-Zoom OPV treat erectile dysfunction (2 blisters x 2 tablets)
Dosage form Box of 2 blisters x 2 tablets
Specifications Tadalafil
Ingredient
| Composition information | Content |
| Tadalafil | 20mg |
Uses
indications
20 mg Re-Zoom drugs are indicated for erectile dysfunction treatment.
Pharmacokic
Tadalafil is a selective inhibitor with restoration of guanosine monophosphate (CGMP) - a special enamel phosphodiesterase type 5 (PDE5).
When sexual stimulation leads to nitric oxyd release, the PDE5 inhibitor of Tadalafil will increase the CGMP concentration in the cave. This leads to smooth muscle relaxation and increases blood pressure into the penis tissue, thereby causing penis.
When there is no sexual stimulation, Tadalafil has no effect.
pharmacokinetic
Tadalafil quickly absorbed through the gastrointestinal tract after drinking. Peak concentration in plasma is 2 hours and is not affected by food.
Tadalafil is widely distributed in tissues and drugs associated with plasma proteins up to 94%. The drug is metabolized in the liver thanks to Cytochrome P450 CYP3A4.
The main metabolites are methylcatechol Glucuronide less active than Tadalafil and have no clinical significant activity. Half of Tadalafil's excretion reached 17.5 hours.
Tadalafil Export mainly into metabolites in feces (61%) and a small portion of urine (about 36%).
The process of output takes place slower in the elderly and patients with kidney function.
Before taking OPV Re-Zoom OPV treat erectile dysfunction (2 blisters x 2 tablets)
How to use
Re-Zoom 20 mg is used orally.
Dosage
for adult men
The starting dose is recommended as Re-Zoom 10 mg, orally from 30 minutes to 12 hours before planning to have sex, not related to meals.
may increase the dose to 20 mg or decrease the dose to 5 mg, depending on the response of each person.
The maximum number of drug use is recommended 1 time/day.
Hepatic failure
Tadalafil is indicated not exceeding 10 mg/day in patients with mild to medium liver failure. Do not use drugs for patients with severe liver function.
kidney failure
No need to adjust the tadalafil dose in patients with a mild renal function (the clearing of creatinine is 51 - 80 ml/min).
In patients with average renal function (Creatinine clearance reaches 31 - 50 ml/minute), start with a dose of 5 mg, should not be used more often once a day. The maximum dosage is specified is 10 mg, not used more often once every 48 hours.
In patients with severe renal impairment (creatinine clearance is lower than 30 ml/minute), including patients with dialysis, should use up to 5 mg, do not use more often once every 72 hours.
Used for diabetics
No need to adjust the dose in diabetics.
Do not use Tadalafil for people under 18.
Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.
What to do when overdose?
In case of overdose, standard support measures should be taken depending on the requirements. Dialysis contributes very little to eliminate Tadalafil.
In an emergency, call the 115 emergency center immediately or go to the nearest local health station.
What to do when forgetting a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.
Side Effects
When using the 20 mg Re-Zoom drug, you may experience unwanted effects (ADR).
Common, ADR> 1/100
Instructions on how to handle ADR
When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
Contraindicated
Against 20 mg re-contraindicated drug in the following cases:
Safety and effectiveness of the drug when used for the groups of patients below have not been established, so Re-Zoom is not recommended for these patients, until there is sufficient information:
Be cautious when using
need to consider the patient's cardiovascular condition, because there may be cardiovascular risks occurring during sexual activity.
Safety and effectiveness of re-zoom combinations and other unprocessed treatments have not been studied. So such combination has not been recommended.
Use carefully for patients with liver, kidney and penile deformity damage.
The ability to drive and operate machinery
Precautions when operating train machinery.
Pregnancy
Not only for this drug for pregnant women. Consult your doctor before using the drug.
Breastfeeding period
Not only for this medication for breastfeeding women. Consult your doctor before using the drug.
Drug interaction
CYP3A4 inhibitors (such as ketoconazol, iTraconazole, ...) can increase the distribution of tadalafil drugs in the body.
When used at the same time, Tadalafil can increase the hypotension effect of calcium inhibitors, enzyme inhibitors, beta blockers and diuretics.
Storage
At temperatures below 30 ° C, avoiding light.
Expiry date: 36 months from the date of manufacture. Do not use drugs when expiry
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