Oral solution A.T Arginin 800 An Thien Treatment maintained hyper ammonia blood (30 tubes x 10ml)

Dosage form Box of 6 blisters x 5 tubes
Specifications Arginin hydrochlorid
Ingredient An Thien

Ingredient

Composition information	Content
Arginin hydrochlorid	800mg

Uses

Indications

AT arginin 800 drugs are indicated in the following cases:

Treatment of blood ammonia maintenance in patients with carbamylphosphate synthetase deficiency, ornithine carbamyl transferase deficiency. Improve the ability to practice in people with stable cardiovascular disease. Learning

arginin 800 is an essential amino acid in the urea cycle for patients who lack enzymes: N-acetylglutamate synthase (NAGS), Carbamyl Phosphate Synthase (CPS), omborin Transcarbamylase (OTC), Arginininsuccinat Synthase (ASSS) Argininosuccinat Lyase (ASL).

Use Arginin hydrochloride for patients with disorders as above to restore arginin levels in the blood and help prevent protein catabolism.

Intermediate products of the Urea cycle are less toxic and easier to eliminate through urine than ammonia and create a selective path for nitrogen elimination process.

arginin 800 increases blood glucose concentration. This effect may be direct effect; The amount of glucose released from the liver is directly associated with the amount of amino acids absorbed. The glycogen prize and glucose fertilizer may also be the intermediary of the arginin process that stimulates Glucagon release.

pharmacokinetics

arginin hydrochloride absorbed well through the digestive tract, the peak concentration in plasma is achieved after about 1 hour.

Arginin hydrochloride closely combines with many biochemical paths. Amino acids are metabolized through the liver to form ornithin and urea by hydrating guanidine under the catalyst of Arginase.

arginin is filtered in glomerular and reabsorbed almost completely in the renal tubules.

Before taking Oral solution A.T Arginin 800 An Thien Treatment maintained hyper ammonia blood (30 tubes x 10ml)

How to use

A.T Arginin 800 is taken orally.

Dosage

Hematoma maintenance treatment in patients with carbamylphosphate synthetase deficiency, ornithine carbamyl transferase deficiency

infant: 100 mg/kg per day, divided 34 times.

Children from 1 month to 18 years old: 100 mg/kg per day, divided 34 times.

Maintain treatment for patients with hyper -hyperconemic blood ammonia with blood citrulin, arguosuccinicuria

infant: 100175 mg/kg/time, use 3-4 times daily with food, adjust the dose according to the response.

Children from 1 month to 18 years old: 100175 mg/kg/time, use 3-4 times daily with food, adjust the dose according to response.

Treatment to support indigestion disorders

Adults, drink 3 - 6 g/day.

Supporting treatment to improve the ability to exercise in people with stable cardiovascular disease

Adults, drink 6-21 g/day, each use no more than 8 g.

Nutrition supplements for people with urea cycle disorders such as hyper ammonia tube I and II, hypercully blood citrulin, arguoSuccinicuria and N-acetyl glutamate synthetase deficiency

Adults, drink 3 - 20 g/day depending on the condition.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Overdose in children can lead to metabolic chlorine, brain edema or may die. Should determine the degree of shortage and calculate the amount of alkaliogens use.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using AT Arginin 800, you may experience unwanted effects (ADR).

Unknown frequency, ADR

immune, allergies: Red rash, swelling of hands and face.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

AT ARGININ 800 drug is contraindicated in the following cases:

Patients with allergies to any ingredients of the drug.

Precautions when using

should stop the drug if diarrhea occurs.

Arginin can change the ratio between extracellular and intracellular, plasma potassium levels can increase when taking arginine for patients with kidney disease or urination.

arginin contains a high level of metabolic nitrogen, so it should evaluate the temporary impact of high amounts of nitrogen on the kidneys before starting treatment with arginine.

Arginin does not have the effect of treating hyperglycemia caused by organic acid disorders and should not be used in the case of above disorders.

The ability to drive and operate machinery

Use for drivers and operate machinery.

Pregnancy

Reproductive studies have been conducted on rabbits and mice at 12 times the dose for humans and no manifestations of fertility decline or damage to arginine fetuses.

There is no complete and controlled research on pregnant women. Because reproductive studies on animals are not always forecasted to be met in humans, so the drug should not be used during pregnancy.

Breastfeeding period

Amino acids are excreted in breast milk in very small amounts that cannot be harmful to the baby. However, be cautious when taking medication in breastfeeding women.

Drug interaction

Insulin concentration in plasma due to arguin stimulation may be higher by diuretics thiazid, xylitol and aminophyllin.

Using oral diabetes medications for long periods of time can inhibit plasma glucagon response to arginin.

When patients intolerant to glucose are used for glucose, phenytoin reduces insulin response in plasma with arginine. Hyperbonemia may occur when using Arginin to treat metabolic alkaline infections for patients with severe liver disease recently using Spironolacton.

Storage

In a dry place, the temperature does not exceed 30 ° C, avoiding light.

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