Oral solution A.T Desloratadin An Thien Huong Strawberry reduces symptoms of allergic rhinitis, urticaria (30ml)

Dosage form Bottle x 30ml
Specifications Desloratadine
Ingredient Allergic rhinitis, urticaria, itching, stuffy nose, rash

Ingredient

Thành phần cho 5ml

Composition information	Content
Desloratadine	2.5mg

Uses

Indications

A.T Desloratadin 2.5mg is indicated in the following cases:

Reduces symptoms in diseases: allergic rhinitis: runny nose, sneezing, stuffy nose, itchy nose and throat, itching, tearing. H1 h1 receptor resistance, highly selected. The receptor base indicates that at a concentration of 2- 3ng/ml, the desloratadine has a significant interaction with a receptor in humans. On Vitro, Desloratadine inhibits humans.

pharmacokinetics

Research results distributed by radioactive isotopes on the mouse indicating that desloratadine does not pass through the brain barrier. By oral, Desloratadine 5mg/time/day, taken for 10 days, the average time to achieve the peak plasma concentration is approximately 3 hours after drinking. Food and fruit juice do not affect the bioavailability of desloratadine. Desloratadine converts into 3 - hydroxydesloratadine, an active and later metabolite into glucuronidate. Enzymes ensure the formation of 3 - hydroxydesloratadine has not been determined. Desloratadine and 3 - Hydroxydesloratadine associated with plasma protein approximately 82% - 87% and 85% - 89%.

The cohesion of desloratadine and 3 - Hydroxydesloratadine does not change patients with renal impairment. Desloratadine waste sale time is 27 hours. CMAX value (plasma peak concentration) and AUC (area under the curve) increased when using a single dose of 5 - 20 mg. Increased accumulation achieved after drinking 14 days suitable for the sale time and regular dose. Human research shows about 87% of the desloratadine dose found in urine and stool in the form of metabolites. In the studies of the puffed skin with a single dose and the repeated dose of 5mg of desloratadine indicates that antihistamine inhibitors effectively after 1 hour and last 24 hours.

Before taking Oral solution A.T Desloratadin An Thien Huong Strawberry reduces symptoms of allergic rhinitis, urticaria (30ml)

How to use

oral A.T Desloratadin once a day.

Dosage

for 5ml drinking tube specifications

Adults and children over 12 years: Take A.T Desloratadin 2 tubes a day.

Children from 6 - 11 years old: Take A.T Desloratadin 1 tube daily.

Children from 2 - 5 years old: Drink A.T Desloratadin daily 1/2 tube.

For packaging specifications

Adults and children over 12 years: Take A.T Desloratadin 2 packs per day.

Children from 6 - 11 years old: Take 1 pack daily.

Children from 2 - 5 years old: Take 1/2 pack daily.

For bottle specifications

Adults and children over 12 years: Take 10ml every day (measuring with the attached cup).

Children from 6 - 11 years old: Take 5ml daily (measure with the attached cup).

Children from 2 - 5 years old: Take 2.5 ml daily (measuring with attached cup).

People with severe liver or kidney failure (Creatinine clearance

Take every two days at a dose of 2 tubes or 2 packs or 10ml (measuring with the attached cup).

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose? In children there are expressions of the tower, brushing the chest.

How to overdose: Desloratadine overdose is usually symptomatic and supportive treatment. Causing vomiting with ipeca syrup, activated carbon. If causing ineffective or contraindicated (patients with fainting, convulsions, lack of vomiting reflexes), the gastric lavage can be carried out with 0.9% sodium chloride solution and intubation to prevent stomach inhalation. Desloratadine is not eliminated by hemorrhage.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using A.T Desloratadin, you may experience some unwanted effects (ADR).

Desloratadine is well tolerated. Desloratadine causes some side effects such as headache, sleep, fatigue, dry mouth, shortness of breath, hangover, abdominal pain, discomfort, dizziness, hypersensitivity reaction.

In children: Usual side effects are diarrhea, fever, insomnia, headache.

Instructions on how to handle ADR: When the side effects of the drug are encountered, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

sensitive to desloratadine or other drugs.

Caution when using

Caution for patients with hepatic impairment.

Safe and effective when using desloratadine for children under 2 years of age has not been determined.

When using desloratadine, there is a risk of dry mouth, especially in the elderly, and increasing the risk of tooth decay. Therefore, it is necessary to clean teeth.

Autodity warning

The ingredient contains sucrose, sorbitol and sucralose, patients with rare genetic disorders such as fructose intolerance, glucose-galactose absorption disorders or enzyme deficiency sucrose-isomaltose should not use this drug.

Methyl paraben, Propyl Paraben is at risk for allergic reactions. Each 5ml of a solution contains 1g of sucrose, 1g of 70%sorbitol, 2.5 mg of sucralose, which should be considered when used for patients with diabetes. Each 5ml of drug solution contains 55mg of propylene glycol, consulting the doctor or pharmacist before giving children the drug, especially when the child is given other drugs containing propylene glycol or alcohol.

The ability to drive and operate machinery

In the treatment dose, the drug does not affect the ability to drive and operate machinery. However, note that headaches, fatigue, sleep, dizziness can occur during treatment.

Pregnancy

There is no full research and good tests for the use of desloratadine during pregnancy.

Breastfeeding period

desloratadine and metabolites Descarboethyloratadine are secreted into breast milk. Therefore only using desloratadine for pregnant and lactating women when necessary, with low doses and short time.

Drug interaction

simultaneously used with ketoconazole, erythromycin or cimetidine, desloratadine concentration in plasma. During testing: 48 hours should be stopped before conducting tests. Drinking desloratadine along with alcohol does not increase the risk of behavior of alcohol.

Cavalry: Due to no studies and the correlation of the drug, do not mix this drug with other drugs.

Storage

In a dry place, the temperature does not exceed 30 ° C, avoiding light.

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