Oral solution Novocough 6mg/ml CPC1HN treat cough symptoms (20 tubes x 5ml)

Dosage form 20 tube box
Specifications Levodropropizine

Ingredient

Composition information	Content
Levodropropizine	6mg

Uses

Indications

Novocough oral solution helps treat symptoms of cough and dry cough.

Pharmacokology

Pharmacological group: Cough reduction. ATC code: R05DB27.

The inhibitory effect of this drug is mainly peripheral, due to the impact on the bronchus.

The drug has little effect on the central nervous system compared to anti -cough drugs that have the effect on the central nerve of Opioid group.

Dynamic pharmacokinetics

Healthy pharmacokinetic studies on healthy mice, dogs and men. Absorption, distribution, metabolism and excretion have been found among three species studied as similar, with bioavailability of over 75%.

Quick absorption and rapid distribution after drinking, absorbing 93%. Linked to negligible plasma proteins (11% - 14%).

Selling time cancel about 1-2 hours. The excretion is mainly through urine. Levodropropizin is excreted both in unprecedented form and in the form of metabolic substances, such as combined levodropropizin, such as p-hydroxylevodropiz-in and combined. The excretion of metabolites in the urine for 48 hours is about 35% of the dose.

Testing, in which the drug is used many times, a batch of eight -day treatment does not change the absorption characteristics and the elimination of the drug. Therefore, the phenomenon of accumulation or automatic touch touch can be excluded. Even in children, in the elderly and in patients with mild or medium renal failure, there is no significant difference in pharmacokinetic properties.

Before taking Oral solution Novocough 6mg/ml CPC1HN treat cough symptoms (20 tubes x 5ml)

How to use

Novocough oral solution recommended for meals.

Dosage

Adults and children over 12 years: 60 mg/time x 3 times/day. Doses 6 hours apart.

Children from 2 to 12 years old: 1 mg/kg x 2-3 times/day, total dose of 3 mg/kg daily, drink at least 6 hours apart.

For convenience, the following dose can be used as follows:

10 - 15 kg: 5 ml x 2 times/day.

16 - 30 kg: 5 ml x 3 times/day.

Specific dose depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose?

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using the drug, there are common unwanted effects (ADR) such as:

Very rare side effects (less than 1: 10000):

Skin and subcutaneous disorders:

allergic rash, urticaria, erythema, rash, itching, angioedema.

Nausea, vomiting, heartburn and stomach pain, indigestion, diarrhea.

Mental disorders:

Very rare: uncomfortable, drowsiness, loss of personality.

Respiratory disorders:

Very rare: shortness of breath, cough, respiratory edema.

Cardiovascular disorders:

Very rare: Brushing chest drum, suspense, tachycardia, hypotension.

Nervous system disorders:

Very rare: fatigue, weakness, drowsiness, headache, drowsiness, dizziness, paralysis.

Very rare: Hypersensitivity reaction.

Notify the physician with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Oral solution of Novocough contraindicated in the following cases:

Hypersensitivity to any ingredients of the drug

This drug is not recommended in patients with bronchial disease, when the situation of increasing secretion is too much mucus, because it can make the patient's condition worse. Age.

Be cautious when using

Preparations containing methyl paraben and propyl paraben may cause allergic reactions.

Novocough should only be used when considering benefits - the risk in patients with severe renal failure.

Novocough should be used carefully in elderly patients.

The effect of the drug on driving and operating machinery

There has been no report on the effect of the drug on the ability to drive and operate machinery, but Levodropropizin can cause unwanted effects as drowsiness, so it is necessary to be cautious when driving or operating machinery.

Use drugs for women during pregnancy and lactation

Pregnant women:

levodropizin passes through the placenta and has been shown to have a harmful effect on the fetus, so it is not allowed to use the drug in pregnant women.

breastfeeding women:

levodropizin is excreted in breast milk. Therefore, do not use drugs in breastfeeding mothers.

Drug interaction

Animal pharmacological studies show that levodropropizin does not enhance the effects of active ingredients acting on central nervous systems (benzodiazepin, phenytoin, imipramin). In clinical pharmacological studies, benzodiazepine also does not change the activity of brain electrical. But still need to be cautious when used simultaneously with sedatives, especially for sensitive patients.

Storage

Store at a temperature not exceeding 30 ° C in the original packaging, avoid moisture and avoid light.

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Disclaimer

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