Oriental Batigan 300mg supports HIV-1 infection, chronic hepatitis B (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Tenofovir disoproxil fumarat
Ingredient HIV/AIDS, hepatitis B

Ingredient

Composition information	Content
Tenofovir disoproxil fumarat	300mg

Uses

Indications

Batigan is indicated in the following cases:

Batigan is indicated for patients with HIV and chronic hepatitis B with liver disease, there is evidence of the virus' copy activity ...

Pharmacokology

Tenofovir is a nucleotide reverse transcriptase inhibitor that has HIV -1 anti -viral activity and hepatitis B. The rapid anti -drug virus when using Tenofovir alone in the treatment of HIV infections, so it is necessary to use with other antiviral drugs.

pharmacokinetics

Tenofovir disoproxil fumarat is quickly absorbed and converted into tenofovir after oral, peak concentration achieved after 1-2 hours.

Birth in diet patients is about 25% but it will increase when Tenofovir Disoproxil Fumarat is drinking when eating high in fat. Tenofovir is widely distributed throughout the body's tissue, especially the kidney and liver.

The connection rate with plasma proteins is below 1% and with serum protein below 7%. Tenofovir elimination half -life is from 12 to 18 hours. Tenofovir excreted mainly through the sub -road.

Before taking Oriental Batigan 300mg supports HIV-1 infection, chronic hepatitis B (3 blisters x 10 tablets)

How to use

Take medicine at meals or when snacks.

The body absorbs the best drugs when taking the medicine at full.

When taking batigan, eat high -fat foods to increase the ability to absorb the drug.

Dosage

Adults

Take 1 capsule/day.

For patients with impaired renal function

Creatinine clearance coefficient: 250ml/min, drink as normal people 300mg/day.

Creatinine clearance coefficient: 30 - 49ml/min, drink 300mg for 2 days.

Creatinine clearance coefficient: 10 - 29ml/min, drink 300mg for 3-4 days.

Patients with hemolysis

Use each dose 7 days apart or after 12 hours of division.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? However, no overdose is prescribed.

Taking more drugs will not improve your symptoms, instead they can cause poisoning or serious side effects.

If you suspect that you or anyone else may have overdosed Batigan, please go to the emergency room at the closest hospital or hospital. Carry a box, shell, or a pharmacy with you to help doctors have the necessary information.

Do not give your medicine to others even though you know they have the same disease or look like they may have the same disease. This can lead to overdose. Please consult your doctor or pharmacist or product package for more information.

What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Batigan, you may experience unwanted effects (ADR). Some side effects recorded in research on users of this drug are:

Common side effects when using Tenofovir Disoproxil Fumarat in the treatment of chronic hepatitis B or with other antiviral drugs in HIV treatment is mild to medium digestive disorders such as anorexia, abdominal pain, diarrhea, indigestion, bloating, nausea and vomiting.

Other common side effects include: dizziness, fatigue, headache. The skin can appear. The concentration of amylase enzymes in serum and pancreas may increase but very rare.

There have been reports on increased liver enzymes, hepatitis, nephritis, nephrogenic diabetes, renal failure, acute renal failure, effect on the adrenal tube including fanconi syndrome.

Lactic acid infection, common in patients with liver or fatty liver when treated with nucleosid reverse enzyme inhibitors.

Immune recovery syndrome (an immune inflammatory reaction that leads to clinical decline) is reported during the first stage of treatment combined with antiviral drugs, including Tenofovir Disoproxil Fumarat, in HIV -infected patients with severe immunodeficiency.

The accumulation or re -distribution of fat in the body (fat formation) including belly fat, fat tumor, peripheral neuropathy, tanning, large breasts and Cushing syndrome appear in patients treated with antiviral drugs, including Tenofovir disoproxil fumarat.

Metabolic disorders such as hypereminemia, hypercholesterolemia, insulin resistance, hyperglycemia, hyperlactic hyperlage have been reported. Nucleosid reverse enzyme inhibitors also cause mucous dysfunction such as behavioral disorders, anemia, convulsions, increased blood lipase, muscle tone and neutropenia.

Hug urinary phosphor, muscle pain, myocarditis and rare muscle pepper have been reported, especially when nucleosid similar substances are used as HIV Protease inhibitors. Bone marrow inflammation has also been reported in HIV patients who have progressed or combined for long -term treatment with antiviral drugs.

Notify the doctor with unwanted effects when using the drug.

This is not a full portfolio of all side effects and may occur other side effects. If you encounter any unwanted effect, stop taking the medication and immediately notify your doctor or immediately go to the nearest medical facility for timely treatment.

Warnings

Before using the drug, you need to read the instructions carefully and refer to the information below:

Contraindicated

Batigan is contraindicated in the following cases:

Children under 18 years old.

Patients with hypersensitivity to the ingredients of the drug.

Severe kidney disease.

Patients with abnormal low neutrophils (

Be cautious when taking the drug

You are allergic to any ingredients of the drug. You should discuss risks and benefits with your doctor.

There is no information on whether this drug will go into breast milk or not. Please consult your doctor before breastfeeding.

In order for the drug to be effective, HIV -infected people need to maintain a high concentration in the blood, which is to take the medication regularly, if for some reason the concentration of the drug is reduced (due to uneven or half -cure medication) will facilitate the production of anti -drug viruses.

Batigan cannot destroy HIV but only prevent their development, so patients need to take medicine continuously for a lifetime.

For all patients, should be cautious when using Batigan.

Not all patients have to use Batigan immediately, only those who have the number of CD4 cells decrease to about 200 - 350/ml will be appointed to use the drug.

Be cautious for patients with renal impairment, liver failure (especially in patients with hepatitis C co -infected with hepatitis C, being treated with interferon A and ribavirin) and patients with a history of fracture, osteoporosis.

The ability to drive and operate machinery

No report

Pregnancy

Mouse and rabbits are pregnant at 14 and 19 times the dose for humans, based on comparisons of the body surface area, there is no evidence of fertility decline or dangerous to the embryo due to tenofovir. However, it is necessary to have research and control on pregnant women. Because reproductive studies on pregnant animals are not always true for people, only Tenofovir is used when it is really necessary during pregnancy.

Breastfeeding period

According to the World Health Organization Control and Prevention Center recommended, HIV-1-infected mothers are not breastfeeding to avoid the risk of HIV-1 infection for children. Research on the mother mouse proves that Tenofovir is excreted in milk, but this has not been known in humans. In order to avoid both HIV-1 transmission and breastfeeding side effects, the mother is advised not to breastfeed if there is treatment with Tenofovir.

Medicine interaction

Labiety can interact with the drugs

This drug may change the ability of other drugs you are taking or increase the effects of side effects. To avoid drug interactions, it is best to write a list of drugs that are used (including prescription, non -prescription, herbal, functional foods) and for doctors or pharmacists. To ensure safety when taking the drug, you do not arbitrarily take the drug, stop or change the dosage of the drug without the permission of a doctor.

Need to control kidney function when using batigan with ganciclovir, valganciclovir.

negligible interaction with methadone.

Batigan can interact with food and drinks

Food, alcohol and tobacco can interact with certain drugs. Consult your doctor about taking medicine with food, alcohol and tobacco.

Health condition affects Batigan medicine

Your health status may affect the use of this drug. Tell your doctor if you have any health problems.

Storage

You should store at room temperature, avoid moisture and avoid light. No storage in the bathroom or in the freezer. You should remember that each drug may have different storage methods. Therefore, you should read carefully storage instructions on the packaging or ask the pharmacist. Keep pills out of reach of children and pets.

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