Ospamox 500mg Imexpharm treats respiratory infections, bronchitis (100 blisters x 10 tablets)

Dosage form Box of 100 blisters x 10 tablets
Specifications Amoxicillin

Ingredient

Composition informationContent
Amoxicillin500mg

Uses

indications

Ospamox drug are indicated in the following cases:

  • Respiratory infections : Upper respiratory tract infections and ENT infection; Lower respiratory infections such as: acute and chronic bronchitis and chronic, pneumonia, pulmonary abscess, pertussis. Due to abortion, side inflammation, endometritis. Learning

    amoxicillin is a broad -spectrum antibiotic with high effect of the penicillin group, in particular, the drug has a short submission time and a broad effect. Like other antibiotics belonging to the penicillin group, the drug works by inhibiting the synthesis of bacterial cell walls.

    The effect of the drug includes both gram -negative and gram -positive bacteria. Clinical gram -negative bacteria are in the effect of Amoxicilin, Escherichia Coli, Proteus Mirabilis, Salmonella, Shigella, Campylobacter, Haemophilus Influenzae, Bordetella Pertussis, as well as Leptospira and Chlamydia.

    Other bacteria also respond to amoxicillin including all types of bacteria sensitive to penicillin G such as: Streptococcinh A, B, C, G, H, L and M; Order; Staphylococcus and Neisseria does not give birth to penicilinase, erysipelothrix rhusiopathiae, corynebacterium, bacillus anthracis, actinomycetes, streptobacilli, spirillium minus, Pasteurella multocida, listeria and other bacteria (Leptospira, Treponema, Borrellia, Borrellia and Borrellia Other bacteria) as well as many types of anaerobic bacteria (including peptococci, peptostreptococci, clostridia and fuso-bacteria).

    pharmacokinetics

    Food does not affect the absorption of amoxicillin. The drug is absorbed almost completely in the small intestine. Peak concentration in serum is achieved after drinking from 1-2 hours.

    Amoxicillin is easily distributed into tissue and fluid fluid, including phlegm and pus secretion of bronchial. If the liver function is intact, the drug achieves very high concentrations in biliary tract. The half-life of amoxicillin is about 1-2 hours. The drug is excreted mainly through the kidneys. More than half the amount of oral medication is excreted in urine in the form of treatment.

    • Before taking Ospamox 500mg Imexpharm treats respiratory infections, bronchitis (100 blisters x 10 tablets)

    How to use

    oral medication. Drinking before or after meals is all due to the ability to absorb the drug not affected by food.

    Dosage

    Adults and children over 10 years old

    Common dose

    1 tablet/time, 3 times/day.

    higher dose

    Take a single dose or in short phases, used in the following cases:

  • 3 g dose, repeat again after 8 hours to treat tanks - Car around the teeth or repeat after 10 - 12 hours to treat uncomplicated urinary tract infections.

    • Preventive pericarditis in humans susceptible: The only dose of 3 g, 1 hour before the procedure such as tooth extraction.

  • Severe or recurrent respiratory infections: 3 g amoxicillin, 2 times/day.

    • Renal failure

    Must reduce the dose according to creatinine clearance coefficient:

    Creatinin clearance coefficient

    Dosage

    500 mg/24 hours

    10 ml/minute

    500 mg/12 hours

    Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

    What to do when overdose?

    What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

    Side Effects

    When using Ospamox 500 mg , you may experience unwanted effects (ADR).

    Unexpected effects are gastrointestinal disorders: nausea, diarrhea . Some rare cases have hypersensitivity reactions such as urticaria, fever, joint pain, diverse roses, flaky dermatitis, vasodilic nerves and hematological disorders such as thrombocytopenia, granular leukopenia, leukopenia and eosinophilia like eosin. Like other antibiotics belonging to the penicillin group, amoxicillin can cause anaphylaxis .

    The risk of manifestations of neurotoxicity (convulsions) can be increased in patients with epilepsy, meningitis or impaired renal function.

    Sometimes there is an increased SGOT liver enzyme, light, transient SGPT.

    Instructions on how to handle ADR

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    Ospamox drug contraindicated in the following cases:

  • Hypersensitivity or suspicion of sensitivity to antibiotics belonging to the penicillin group. It is important to note that cross -allergies in patients are sensitive to cephalosporin antibiotics.
  • Do not use oral amoxicillin to treat severe gastrointestinal infections with prolonged diarrhea or vomiting because of the risk of reducing drug absorption.

    • Need to be particularly cautious in patients with allergies, bronchial asthma .

    Be cautious when using

    If allergic reactions occur, need to stop the drug and conduct treatment with epinephrin, antihistamine and corticoids.

    Patients with cholecystitis or cholecystitis only drink amoxicillin when the disease is not serious and does not accompanied by bile obstruction.

    Should monitor liver function when taking the drug for a long time at high doses. Patients with kidney disease in advance or skin rash appears should be conducted with a total urine analysis test and kidney function assessment tests. Monitoring blood formula to detect hemolytic anemia and reactions related to antibodies of the hematopoietic system.

    During prolonged treatment, attention should be paid to excessive growth of anti -drug and fungal bacteria. Secondary infection should be treated with appropriate measures.

    When there is severe and prolonged diarrhea, it is recommended to monitor fake colitis caused by antibiotics (diarrhea, mucus, blood streaks; abdominal cramps or dull pain spread; fever and sometimes feel).

    The ability to drive and operate machinery

    The drug does not affect the ability to drive and operate machinery.

    pregnancy

    Amoxicillin safely used during pregnancy has not been clearly defined. Therefore, only this drug is needed during pregnancy. However, there is no evidence of harmful effects for the fetus when using amoxicillin for pregnant women.

    Lactation period

    Because amoxicillin is excreted in breast milk, it is necessary to be cautious when taking the drug during breastfeeding.

    Drug interactions

    oral Allopurinol at the same time can promote the appearance of a rash in the skin. The mechanism of this phenomenon still does not understand.

    Do not coordinate with a bactericidal antibiotic, such as tetracyclin and chloramphenicol because penicillin antibiotics such as amoxicillin only acts on growth bacteria. It is possible to combine drugs with other antibacterial antibiotics (cephalosporin, aminoglycosides) according to the test of bacterial sensitivity.

    Simultaneous use of probenecid (eg 0.5 g drink 4 times/day, contraindicated in children under 2 years old) increases and maintains drug concentration in plasma by reducing the excretion of the kidneys. In contrast, the distribution into tissue and diffusion of spamox may be reduced by probenecid.

    Like other antibiotics, aminopenicilin can reduce the effectiveness of birth control pills in some cases.

    Concentrated antacids reduces the absorption of amoxicillin.

    Testing for seeking glucose by non -yeast method can give false positive results.

    Urobilinogen tests may also be false.

    Storage

    Store at temperatures below 30 ° C, avoid moisture and light.

    Other drugs

    Disclaimer

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