Otrivin nose drops 0.1% GSK treat nasal congestion, nasal congestion (10ml)
Dosage form Small nose solution
Specifications Bottle x 10ml
Ingredient Xylometazoline
Indication Sinusitis, stuffy nose, nasal congestion
Contraindication Cardiovascular disease, high blood pressure
Ingredient
| Composition information | Content |
| Xylometazoline | 0.1% |
Uses
indications
Otrivin nose drops of 0.1%are indicated in the following cases:
ATC code: RO1A AO7.
Mechanism of impact
Otrivin belongs to the sympathetic strength group on the alpha-adrenergic receptors and is used for nasal lines. It causes blood vessels in the nose, thereby reducing edema in the nasal mucosa and surrounding surrounding throat. This helps patients with colds can breathe through the nose more easily. The effect of Otrivin starts within minutes and lasts up to 10 hours.
Otrivin is generally good tolerance and does not affect the function of vibrating hair.
In a double blind study, verifying the salt solution (Otrisal) in patients with a common cold, the nose effect of Otrivin remains significantly (P
Otrivin tolerates well, even in patients with sensitive nasal mucosa, and does not affect the function of the feather in the mucosa.
In-Vitro studies show that Xylometazoline Hydrochloride reduces the infectious activities of Rhinoviruses related to common colds.
Otrivin has a balanced pH within the range found in the nasal cavity.
Otrivin contains pleasant excipients to help prevent dryness and stimulate the nasal mucosa.
Dynamic pharmacokinetics
Xylometazoline concentration in plasma after use in the nose is very low and near the detection limit.
absorption
Taking medication on the spot leads to very little body absorption. However, the absorption of the body of Xylometazoline in the nose occurs and can lead to side effects such as the sympathetic nerve effect when the recommended dose is exceeded.
distribution
No data from human studies.
transformation
No data from human studies.
Elimination
No data from human studies.
Before taking Otrivin nose drops 0.1% GSK treat nasal congestion, nasal congestion (10ml)
How to useHow to use Otrivin nose small solution:
Recommendations should be used for the last time before going to bed.
Be careful not small in the eyes.
- Clean the nose. Avoid spreading possible infections, vials should only be used by one person.
Dosage
should not use Otrivin 0.1% for children under 12 years old.
Do not take the drug for more than 7 consecutive days.
Do not overdose recommended especially children and the elderly.
age Dosage Maximum daily dose Use 2 or 3 times daily if necessary.
- Not more than 3 times a day on each nose. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.
What to do when overdose?
Signs
Overdose or accidentally swallowing xylometazoline hydrochloride can cause serious dizziness, sweat, reduce serious body temperature, headache, slow heartbeat, hypertension, respiratory failure, coma and convulsions. Hypertension may occur after hypotension. Young children may be more prone to poisoning than adults.
Treatment
should take appropriate support measures on all patients who are suspected of overdose and indicate emergency symptom treatment under medical supervision when guaranteed. This will include monitoring patients for a few hours.
What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double doses to compensate for missed dose.
- Not more than 3 times a day on each nose. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.
Side Effects
When using 0.1%Otrivin nose drops, you may experience unwanted effects (ADR).
The adverse reaction is listed below, classified by the organ system and frequency. The frequency is defined as follows: Very common (≥ 1/10), common (≥ 1/100 to
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
Contraindicated
Otrivin nose drops 0.1% contraindicated in the following cases:
Caution when using
should not use Otrivin for more than 7 consecutive days. Like other drugs of the same active ingredient group, xylometazoline should be used carefully in patients too sensitive to sympathetic drugs, manifested through symptoms of insomnia, dizziness, ...
Be cautious in patients with hypertension, cardiovascular, hyperthyroidism or diabetes, chrome cell tumors, prostate hypertrophy, patients who are using monoamine oxidase inhibitors (Mao inhibitors) or Mao inhibitors in the past 2 weeks.
Caution and warning in the labeling section
Precautions and warnings in the user manual
affects the ability to drive and operate machinery
Otrivin does not affect or negligible on the ability to drive and operate machinery.
pregnancy and lactation
fertility
There is no adequate data on the effects of xylometazolinehydrochloride on fertility and no animal research.
Pregnancy
Because it may have a systemic vascular effect, it does not use Otrivin during pregnancy.
Breastfeeding period
There is no evidence of any adverse effects on breastfed babies. However, it is not known whether the xylometazoline will be excreted in breast milk, so during breastfeeding should be cautious when using Otrivin and should only be used under the guidance of medical staff.
Medicinal interaction
simultaneous use of xylometazoline with Mao inhibitors or antidepressants 3, 4 rounds can cause hypertension because these substances affect cardiovascular disease.
Storage
Leave a cool place, avoid light, temperature below 30⁰C.
To be out of reach of children, read the user manual carefully before use.
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Disclaimer
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