Otrivin nose spray 0.05% GSK reduces symptoms of nasal congestion, allergic rhinitis (10ml)
Dosage form Nasal spray solution
Specifications Bottle x 10ml
Ingredient Xylometazoline hydrochloride
Indication Nasal congestion, nasal congestion
Contraindication Cardiovascular disease, diabetes (diabetes), high blood pressure
Ingredient
| Composition information | Content |
| Xylometazoline hydrochloride | 0.05% |
Uses
indications
Otrivin 0.05% of the spray form is indicated to reduce the symptoms of nasal congestion related to conventional colds, allergic rhinitis and recurrence (including colds), sinusitis.
Pharmacokinatus
Treatment group: Nas that nose is used on the spot, Cuong sympathize.
ATC code: RO1A A07.
Mechanism of impact
Otrivin belongs to the sympathetic strength group on the alpha-adrenergic receptors and is used for nasal lines. It causes blood vessels in the nose, thereby reducing edema in the nasal mucosa and surrounding surrounding throat. This helps patients with colds can breathe through the nose more easily. The effect of Otrivin starts within minutes and lasts up to 10 hours.
Otrivin is generally good tolerance and does not affect the function of vibrating hair.
In a double blind study, verifying the salt solution (Otrisal) in patients with common colds, the nose effect of Otrivin remains significantly (p
Otrivin tolerates well, even in patients with sensitive nasal mucosa, and does not affect the function of the feather in the mucosa.
In-Vitro studies show that Xylometazoline Hydrochloride reduces the infectious activities of Rhinoviruses related to common colds.
Otrivin has a balanced pH within the range found in the nasal cavity.
Dynamic pharmacokinetics
Xylometazoline concentration in plasma after use in the nose is very low and near the detection limit.
absorption
Taking medication on the spot leads to very little body absorption. However, the absorption of the body of Xylometazoline in the nose occurs and can lead to side effects such as the sympathetic nerve effect when the recommended dose is exceeded.
distribution
No data from human studies.
transformation
No data from human studies.
Elimination
No data from human studies.
Before taking Otrivin nose spray 0.05% GSK reduces symptoms of nasal congestion, allergic rhinitis (10ml)
How to use
Sugar used: Spray nasal.
Do not overdose.
Recommendations should be used for the last time before going to bed.
Nasal spray has an accurate dose and ensures that the solution is well distributed on the surface of the nasal mucosa. Can prevent the possibility of overdose due to unintentional.
Each nasal spray has an Otrivin dose of 0.05% distribution of 0.07 ml/ spray (0.035 mg of xylometazoline hydrochloride).
Before using it for the first time, the bait pumped by booting 4 times. After the pump bait, the pump will recharge normally during daily treatment. If the drug is not sprayed during the boot, or if the product has not been used for more than 7 days, it is necessary to bait pump again by booting twice.
Be careful not to spray into the eyes.
- clean the nose. Lan infection may have, bottles should only be used by one person. Dosage
Adults and older adults: Not applicable.
contraindicated use of 0.05% Otrivin for children under 6 years old.
Children from 6 years old to 12 years old (for all indications): 1-2 times spray on each side of the nose, 1 or 2 times daily.
Do not use Otrivin for more than 5 days without a doctor's advice. Parents or caregivers of children should go to the health facility if the child's condition worsens during treatment.
Do not use more than 2 doses within 24 hours.
What to do when overdose?
Signs
Overdose or accidentally swallowing xylometazoline hydrochloride can cause serious dizziness, sweat, reduce serious body temperature, headache, slow heartbeat, hypertension, respiratory failure, coma and convulsions. Hypertension may occur after hypotension. Young children may be more prone to poisoning than adults.
Treatment
should take appropriate support measures on all patients who are suspected of overdose and indicate emergency symptom treatment under medical supervision when guaranteed. This will include monitoring patients for a few hours.
What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.
Side Effects
When using Otrivin 0.05% spray, you may experience unwanted effects (ADR).
The adverse reaction is listed below, classified by the organ system and frequency. The frequency is defined as follows: Very common (≥ 1/10), common (≥ 1/100 to
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
Contraindicated
Otrivin 0.05% contraindications in the following cases:
Be cautious when using
need to be very careful when taking the drug for patients in the following cases:
The effect of drugs on driving and operating machinery
Otrivin does not affect or negatively affect the ability to drive and operate machinery.
Use drugs for women during pregnancy and lactation
fertility
There is no adequate data on the effects of xylometazoline hydrochloride on fertility and no animal studies.
Pregnancy
Because it may have a systemic vascular effect, it does not use Otrivin during pregnancy.
Breastfeeding period
There is no evidence of any adverse effects on breastfed babies. However, it is not known whether the xylometazoline will be excreted in breast milk, so during breastfeeding should be cautious when using Otrivin and should only be used under the guidance of medical staff.
Medicinal interaction
simultaneous use of xylometazoline with Mao inhibitors or antidepressants 3, 4 rounds can cause hypertension because these substances affect cardiovascular disease.
Storage
Storage below 30 ° C. Avoid heat.
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