Otrivin nose spray 0.1% GSK treat nasal congestion, nasal congestion (10ml)

Dosage form Nasal spray solution
Specifications Bottle x 10ml
Ingredient Xylometazoline hydrochloride
Indication Middle otitis
Contraindication Rhinitis

Ingredient

Composition informationContent
Xylometazoline hydrochloride0.1%

Uses

Indications

Otrivin 0.1% Nasal Spray is indicated in the following cases:

  • Reduce symptoms of nasal congestion, allergic rhinitis and recurrence (including sensitivity), sinusitis. It causes blood vessels in the nose, thereby reducing edema in the nasal mucosa and surrounding surrounding throat. This helps patients with colds can breathe through the nose more easily. The effect of Otrivin starts within minutes and lasts up to 10 hours.

    Otrivin is generally good tolerance and does not affect the function of vibrating hair.

    In a double blind study, verifying the salt solution (Otrisal) in patients with a common cold, the nose effect of Otrivin remains significantly (P

    Otrivin tolerates well, even in patients with sensitive nasal mucosa, and does not affect the function of the feather in the mucosa.

    In-Vitro studies show that Xylometazoline Hydrochloride reduces the infectious activities of Rhinoviruses related to common colds.

    Otrivin has a balanced pH within the range found in the nasal cavity.

    Otrivin contains pleasant excipients to help prevent dryness and stimulate the nasal mucosa.

    Dynamic pharmacokinetics

    Xylometazoline concentration in plasma after use in the nose is very low and near the detection limit.

    absorption

    Taking medication on the spot leads to very little body absorption. However, the absorption of the body of Xylometazoline in the nose occurs and can lead to side effects such as the sympathetic nerve effect when the recommended dose is exceeded.

    distribution

    No data from human studies.

    transformation

    No data from human studies.

    Elimination

    No data from human studies.

    • Before taking Otrivin nose spray 0.1% GSK treat nasal congestion, nasal congestion (10ml)

    How to use

    recommend last to use right before going to bed.

    Nasal spray has an accurate dose and ensures that the solution is well distributed on the surface of the nasal mucosa. Can prevent the possibility of overdose due to unintentional. Each nasal spray has 0.1% willow stool distribution 0.14 ml/spray (0.14 mg of xylometazoline hydrochloride).

    Before using it for the first time, the bait pumped by booting 4 times. After the pump bait, the pump will recharge normally during daily treatment. If the drug is not sprayed during the boot, or if the product has not been used for longer than 7 days, it is necessary to bait pump again by booting 4 times.

    Be careful not to spray into the eyes.

    1. clean the nose. Yes, the bottle should only be used by one person. 3 times a day if necessary. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

      What to do when overdose?

      Signs

      Overdose or accidentally swallowing xylometazoline hydrochloride can cause serious dizziness, sweat, reduce serious body temperature, headache, slow heartbeat, hypertension, respiratory failure, coma and convulsions. Hypertension may occur after hypotension. Young children may be more prone to poisoning than adults.

      Treatment

      should take appropriate support measures on all patients who are suspected of overdose and indicate emergency symptom treatment under medical supervision when guaranteed. This will include monitoring patients for a few hours.

      What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

    Side Effects

    When using 0.1% Otrivin Nasal Spray you may experience unwanted effects (ADR).

    The adverse reaction is listed below, classified by the organ system and frequency. The frequency is defined as follows: Very common (≥ 1/10), common (≥ 1/100 to

    Classification Sutta headache common

    Increased heart rate

    Very rare

    Very rare

    Uncomfortable feeling in the nose

    Appearance in children and babies

    popular

    Popular

    Very rare

    gastrointestinal disorders - nausea

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    contraindicated

    Otrivin 0.1% Nasal Spray is contraindicated in the following cases:

  • Hypersensitivity to xylometazoline or any excipients of the drug.

    Caution when using

    should not use Otrivin for more than 7 consecutive days. Like other drugs of the same active ingredient group, xylometazoline should be used carefully in patients too sensitive to sympathetic drugs, manifested through symptoms of insomnia, dizziness, ...

    Be cautious in patients with hypertension, cardiovascular, hyperthyroidism or diabetes, chrome cell tumors, prostate hypertrophy, patients who are using monoamine oxidase inhibitors (Mao inhibitors) or Mao inhibitors in the past 2 weeks.

    Caution and warning in the labeling section

  • Do not overdose indicated.
  • Do not use more than 7 consecutive days. Because use that extends vessels or excess may cause corresponding hemorrhage and/or nasal mucosa. If the symptoms are persistent, see a doctor. Should use the vial for longer than 28 days after opening the lid for the first time.

    Precautions and warnings in the user manual

  • Do not take the drug if you are sensitive to any component of Otrivin. Vomiting and headache are rarely occurring.

    • The ability to drive and operate machinery

    Otrivin does not affect or negligible on the ability to drive and operate machinery.

    pregnancy and lactation

    fertility

    There is no adequate data on the effects of xylometazolinehydrochloride on fertility and no animal research.

    Pregnancy

    Because it may have a systemic vascular effect, it does not use Otrivin during pregnancy.

    Breastfeeding period

    There is no evidence of any adverse effects on breastfed babies. However, it is not known whether the xylometazoline will be excreted in breast milk, so during breastfeeding should be cautious when using Otrivin and should only be used under the guidance of medical staff.

    Medicinal interaction

    simultaneous use of xylometazoline with Mao inhibitors or antidepressants 3, 4 rounds can cause hypertension because these substances affect cardiovascular disease.

    Storage

    Leave a cool place, avoid light, temperature below 30⁰C.

    To be out of reach of children, read the user manual carefully before use.

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