Ovalax 5mg Traphaco laxative treatment for constipation, cleansing intestines (1 blister x 10 tablets)

Dosage form Film cover tablets in the intestine
Specifications Box of 1 blister x 10 tablets
Ingredient Bisacodyl
Indication Constipation
Contraindication Acute appendicitis, bowel obstruction

Ingredient

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Composition information	Content
Bisacodyl	5mg

Uses

indications

Ovalax® drug is indicated in the following cases:

Treatment of constipation.

Preparation of colon X-ray. The drug has a direct effect on the intestinal smooth muscles, stimulating the nerve puppet in the intestinal wall mainly in the colon, so it increases the peristalsis of the colon. At the same time, inhibiting the reabsorption of water in the intestine, leading to increased water accumulation and electrolytes in the colon. Therefore, Bisacodyl stimulates defecation, reduces defecation time and softens stool.

bisacodyl has the main impact on the lower part of the digestive tract and does not affect the digestive process and absorption of nutrients in the small intestine.

Dynamic pharmacokinetics

After drinking, bisacodyl is quickly hydrolyzed by the intestinal enzyme in the intestinal form to form an active form of bis (p-hydroxyphenyl) -Pyridyl-2-methan (BHPM). The plasma concentration of BHPM peaks from 4 to 10 hours after drinking, the laxative effect appears after drinking 6 - 12 hours. The laxative effect of Bisacodyl is not correlated with the plasma bhpm concentration but instead, BHPM acts at the lower part of the digestive tract. That is why Bisacodyl is formulated in the form of tablets in the intestine so that it can be released mainly in the colon - the desired effect.

Small amount of absorption drug is conjugated in the intestinal wall and liver forming the inactivated form of glucuronid bhpm. Half a lifetime of BHPM Glucuronid is about 16.5 hours. On average, 51.8 % of the drug is eliminated in feces in the form of BHPM and an average of 10.5 % of the drug is eliminated through the urine in the form of BHPM Glucuronid.

Before taking Ovalax 5mg Traphaco laxative treatment for constipation, cleansing intestines (1 blister x 10 tablets)

How to use

Take oral use.

swallow the whole pill (do not chew, break). Take medicine away from milk or antacids 1 hour. Should take medicine in the evening before going to bed.

Dosage

CONSTRUCTION TREATMENT

Adults and children over 10 years old: 1 - 2 capsules/time/day.

Children 4 - 10 years old: 1 tablet/time/day. If you treat chronic or prolonged constipation, you must follow your doctor's instructions.

Preparation of colon X-ray or surgery

as directed by the doctor. Often use combination of oral medications and rectal drugs to completely remove the intestine.

Adults and children over 10 years old: Take 2 capsules in the morning and 2 capsules in the evening before the procedure and place 1 tablet of 10 mg the next morning, before taking a scan or surgery.

Children 4 - 10 years old: Take 1 capsule in the evening before the procedure and place a rectum of 1 tablet 5 mg the next morning, before taking a scan or surgery.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms of overdose

diarrhea, abdominal spasms, which show dehydration, potassium and clinical electrolytes. Using long -term overdose can cause chronic diarrhea, abdominal pain, hypokalemia, secondary aldosteron, kidney stones, renal tubular lesions, metabolic alkaline infections, secondary abnormalities due to hypokalemia in combination with chronic laxative abuse.

Handling

Minimize the absorption of bisacodyl by causing vomiting or gastric lavage. Maintain rehydration and monitor serum potassium, pay special attention to adjust the electrolyte balance, especially in the elderly and children. Anti -spasms may be somewhat valid.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Ovalax®, you may experience unwanted effects (ADR).

Unwanted effects when using Bisacodyl short -term short -term light and self -out. The most common unwanted effect is abdominal pain, diarrhea. Should swallow the whole pill (do not chew, break), reduce the dose if diarrhea.

digestive system

Common

: abdominal pain, abdominal spasms, diarrhea, nausea.

Less: vomiting, bloating, discomfort in the anus, rectum, blood mixed in stool.

Rare: colitis.

Metabolism and nutrition

Rare: dehydration.

Nervous system.

Less: dizziness.

Rare: fainting.

immune system

Rare: Anaphylactic reactions, angels, hypersensitivity.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Ovalax® drug contraindicated in the following cases:

Intodia, acute abdominal pain includes appendicitis, acute bowelitis.

Severe dehydration.

sensitive to bisacodyl or any ingredients of the drug.

Be cautious when using

Do not take the drug for more than 5 days without finding out the cause of constipation.

Prolonged medication can lead to imbalance of water, electrolytes and hypokalemia. Dehydration of intestinal water can lead to dehydration, harmful to people with kidney failure, elderly people, need to be cautious when using drugs for this object.

Laxatives do not help lose weight.

Prolonged medication can cause muscle tone loss, reduce intestinal activity.

may appear blood in the stool, but this condition is usually mild and recovered.

Dizziness and/or fainting have been recorded in patients taking drugs containing bisacodyl. The details obtained from these cases suggest that these symptoms are suitable for fainting when defecation (fainting due to exertion), or with vagus neuropathy reflexes caused by constipation abdominal pain, causing patients to use laxatives rather than necessarily using Bisacodyl.

There are reports on abdominal pain and blood diarrhea after using bisacodyl. In some known cases, it is related to anemia of colon mucosa. Children under 10 years old using Ovalax® need advice from health workers. Do not use for children under 4 years of age because of the inappropriate formation.

The drug contains lactose, patients with rare genetic disorders Galactose, Lapp - Lactase or Glucose - Galactose abnormal abnormalities should not use this drug.

The ability to drive and operate machinery

No research on the influence of Bisacodyl on the ability to drive and operate machinery. However, if the patient has abdominal pain, spasms, at risk of dizziness or fainting due to using Bisacodyl, you should avoid driving or operating machinery.

Pregnancy

There is no complete and controlled research on the influence of bisacodyl in pregnant women. There is currently no evidence that pregnant women have unwanted effects or miscarriage when using bisacodyl.

However, like all other drugs, Ovalax® should not be used during pregnancy, especially in the first three months, unless the benefits are expected to be greater than any possible risk.

Lactation period

Clinical data shows that the activity of bisacodyl (BHPM) and its glucuronid complex is not excreted in milk.

However, like all other drugs, Ovalax® should not be taken during breastfeeding unless the benefits are expected to be greater than any risk possible.

Medicinal interaction

Use Ovalax® simultaneously with gastric and milk antacids, reducing the acid resistance of the intestinal solubility layer. The drug can disintegrate early in the stomach can lead to indigestion and stimulate the stomach.

high doses of ovalax® and diuretics and corticosteroids increase the risk of electrolyte imbalance. Electrolyte imbalance can lead to an increase in cardiac Glycosides.

Storage

Store in a dry place, the temperature does not exceed 30ºC, avoiding light.

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