Panadol 500mg Panadol tablets relieve pain, fever, headache treatment, muscle pain (10 blisters x 12 tablets)

Dosage form Film bag tablets
Specifications Box of 10 blisters x 12 tablets
Ingredient Paracetamol

Ingredient

Composition information	Content
Paracetamol	500mg

Uses

Indications

Panadol 500mg drug is indicated in the following cases:

Mild to medium to medium pain treatment: headache, migraine, muscle aches, dysmenorrhea, sore throat, muscular pain, fever and pain after vaccination, pain after tooth extraction or after dental procedures, toothache, osteoarthritis pain. Pain, fever. The mechanism of action of the drug is thought to inhibit the synthesis of prostaglandin, mainly in the central nervous system.

Due to the no effect of inhibiting peripheral prostaglandin, the drug has an important pharmacological properties of maintaining prostaglandin to protect the digestive tract. Therefore, Paracetamol is suitable for patients with a history of disease or patients who are taking other drugs with side effects are inhibiting peripheral prostaglandin (for example, patients with a history of gastrointestinal bleeding or the elderly).

pharmacokinetic

absorption

Paracetamol is absorbed quickly and almost completely from the digestive tract.

Distribution

At the treatment concentration, paracetamol binds very little with plasma proteins.

Metabolism

paracetamol is metabolized in the liver and excreted in urine mainly in the form of glucuronide and sulfate.

Elimination

less than 5% paracetamol is excreted in a constant form.

Before taking Panadol 500mg Panadol tablets relieve pain, fever, headache treatment, muscle pain (10 blisters x 12 tablets)

How to use

Panadol 500mg drug used orally.

Dosage

Adults (including the elderly) and children aged 12 and older: Use 500 mg to 1 g of paracetamol (1 - 2 capsules/time), after every 4-6 hours if needed.

Maximum daily dose: 4000 mg (8 tablets).

Do not overdose prescribed, not used with other drugs containing paracetamol.

Minimum dose distance: 4 hours.

Children from 6 to 11 years old: Use 250 - 500 mg after every 4-6 hours if needed.

Maximum daily dose: 60 mg/kg of weight divided into several times, each time 10 - 15 mg/kg weight used for 24 hours.

Do not overdose prescribed, not used with other drugs containing paracetamol.

Do not use more than 4 doses in 24 hours.

Minimum dose distance: 4 hours. Maximum time of using drugs without advice from a doctor: 3 days.

Children under 6 years of age: Do not recommend using drugs for children under 6 years old.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

may need n-acetylcysteine or methionine.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using green panadol, you may experience unwanted effects (ADR).

Very rare, ADR

Blood and lymphatic system: platelets.

The immune system: Hypersensitivity reaction, sensitive reaction on the skin such as erythema, angioedema, Stevens - Johnson syndrome.

Respiratory, chest and mediastinum: bronchospasm in patients sensitive to aspirin and other NSAIDs.

Liver: Liver abnormalities.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Panadol 500mg drug contraindicated in the following cases:

History of hypersensitivity to paracetamol or any excipients of the drug.

Be cautious when using

Doctors need to warn patients on signs of serious skin reactions such as Stevens - Johnson syndrome (SJS), toxic skin necrosis syndrome (Ten) or Lyell syndrome, acute overseas acne syndrome (AGEP).

There is an increase in the risk of paracetamol harmful to the liver in patients with liver diseases. Patients diagnosed with liver or renal failure should consult a doctor before taking this medication.

If the symptoms are persistent, consult a doctor.

To be out of reach of children.

The ability to drive and operate machinery

The drug does not seem to affect the ability to drive and operate machinery.

Pregnancy

Human and animal studies have not yet identified any risk of paracetamol for pregnancy or embryo development.

Breastfeeding period

Human studies with paracetamol cannot identify any risk for nursing or breastfeeding women.

paracetamol passes through the placenta and is excreted into breast milk.

Drug interaction

Use the daily daily paracetamol that increases the anticoagulant effect of warfarin and other types of cooumarin leading to an increased risk of bleeding; Non -regular use will not have a significant impact.

Storage

Store in a dry place, less than 30ºC.

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Disclaimer

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