Panangin Gedeon injection treatment for heart failure, myocardial infarction, arrhythmia (5 tubes x 10ml)

Dosage form Box of 5 tubes x 10ml
Specifications Magnesium aspartate, potassium aspartat khan

Ingredient

Composition information	Content
Magnesium aspartate	400mg
Potassium Aspartat Khan	452mg

Uses

indications

Panangin drugs are indicated in the following cases:

Panangin infusion solution contains potassium and magnesi ions, which are used in the treatment of some chronic heart disease (heart failure, post -myocardial infarction) and arrhythmia (mainly ventricular arrhythmia). The drug is also used for additional treatment with digitalis.

Pharmacological

Mg ++ and K+ are intracellular cations, playing an important role in the function of many enzymes, linking molecules to cell elements and in the molecular mechanism of muscle spasms. The spasm of myocardial muscle is affected by the percentage of intracellular and extracellular concentrations K+, Ca ++, Na+, Mg ++.

Aspartat is endogenous, acting as an appropriate ion transportation: Due to strong affinity to cells and sub -separating Aspartat salts, ions penetrate the cell in the form of complex. Potassium - Magnesi Aspartat stimulates myocardial metabolism. The deficiency of potassium and magnesium can contribute to hypertension, coronary artery disorders, arrhythmia and cardiomyopathy.

pharmacokinetics

Magnesi

The total amount of mg ++ in the average body is 24 g (1000 mmol) in humans weighing 70 kg, over 60% in bones, nearly 40% in skeletal muscle and other tissues. Approximately 1% of Mg ++ in the body is in extracellular fluid, mainly in the blood. In normal adults, serum serum magenesi concentration ranges from 0.70 - 1.10 mmol. The kidney is the main organ that regulates the Magnesi balance. 3 - 5% Magnesi ionization is excreted in urine.

Potassium

The average amount of K+ in the body is 140 g (3570 mmol) in people weighing 70 kg. 2% of K+ is outside the cell, 98% is in the cell.

The amount of K+ absorbed daily, optimal is 3 - 4 g (75 - 100mmol). In the long run, the kidneys are responsible for keeping the home's home home balance as well as serum potassium concentration. In the short term, potassium concentration can be air -conditioned by in intra -intracellular and extracellular movement.

Before taking Panangin Gedeon injection treatment for heart failure, myocardial infarction, arrhythmia (5 tubes x 10ml)

How to use

only use medication by vein, slow intravenous infusion.

Dosage

dilute 1 - 2 panangin tubes with 50 - 100 ml of 5% glucose solution (at least 50 ml of glucose solution for each tube), slow drip intravenous fluid.

If necessary, the dose can be repeated every 4 - 6 hours. Panangin is suitable for combined treatments.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

No report on overdose use. If an overdose occurs, symptoms may be experienced by hyperpass and blood magnesium. Symptoms of hyperkalemia: The condition of fatigue, muscle weakness, abnormalities, loss of cognition, abnormal heart function (slow heart rate, atrial block, arrhythmia, cardiac arrhythmic).

Symptoms of blood magnesia: reducing nervous excitement, nausea, vomiting, sleeping, lowering blood pressure, losing tendon reflexes (when blood magnesium concentration increases too high), respiratory paralysis, coma. When an overdose, stop using Panangin and treat symptoms (intravenous calcium chloride solution 100 mg/min, dialysis if necessary).

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Panangin you may experience unwanted effects (ADR).

When fluid can be encountered symptoms of hyperboly/magnesium blood.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Panangin drugs contraindicated in the following cases:

Acute or chronic renal failure.

Adison disease (adrenal impairment).

Atrial block of III.

Cardioma (blood pressure below 90 mmHg).

Be cautious when using

If the fluid can be flushed quickly.

Be cautious for patients with disease with hyperkalemia. Must check the ion ion and base acid regularly.

The safety and effectiveness of Panangin in children and young people have not been established.

The ability to drive and operate machinery

Panangin does not affect the ability to drive and operate machinery.

Pregnancy

There is currently no facts about the harmful effects of Panangin injection on these objects.

The period of breastfeeding

There is currently no data on the harmful effects of Panangin injection on these objects.

Interactive drug

There is no drug interaction research with Panangin. Based on literature, potassium and magnesi can interact with some drugs.

When using simultaneously Panangin with potassium and/or enzyme inhibitors, angiotensin conversion, beta, cyclosporin, heparin and non -steroid anti -inflammatory drugs that can lead to hyperboly.

Storage

Store in a dry place, at a temperature not exceeding 30 ° C.

Other drugs

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