Panangin Gedeon tablets supplement potassium, Magnesi used in heart failure (50 tablets)

Dosage form Box of 50 capsules
Specifications Potassium aspartat anhydrous, magnesium

Ingredient

Composition information	Content
Potassium Aspartat Khan	158mg
Magnesium	140mg

Uses

indications

Panangin drug are indicated in the following cases:

Additional potassium and magnesi in:

Some chronic heart disease such as heart failure or post -myocardial infarction, with the consent of the treating doctor;

Some arrhythmia (mainly ventricular arrhythmia), with the consent of the treating doctor;

Cases of not adequate ion intake or power outage, for example, when using long -lasting diuretics, causing potassium loss such as thiazid diuretics (such as hydrochlorothiazide , indapamid) or strap diuretic (such as Furosemid).

Pharmacological

The active ingredients in Panangin plays an important role in many metabolic cycles and in the cardiovascular, muscular and nervous system. Mg ++ and K+ are intracellular cations, which play an important role in the functional activity of many enzymes, in the activity of molecular molecules with the elements under the cell and in the molecular mechanism of muscle spasms.

The ratio between intracellular concentration and extracellular concentration of K+, Ca ++, Na+, Mg ++ ions plays a role in the spasm of the heart muscle. Aspartat is endogenous, acting as an appropriate ion transportation: Due to strong affinity to cells and sub -separating aspartats, ions enter the cell in the form of complex. Potassium - Magnesi Aspartat improves the metabolism of the heart muscle.

Dacection of potassium and magnesi increases the risk of hypertension, coronary artery disorders, arrhythmia and myocardial disease.

pharmacokinetics

Magnesi

The average mg ++ amount in the body is 24g (1000 mmol) in humans weighing 70 kg over 60% exist in bones, nearly 40% in skeletal muscle and other tissues. Approximately 1% of the amount of mg ++ totaling the body of the body exists in extracellular fluid, mainly in the blood. In normal adults, serum magnesium concentration is about 0.70 - 1.10 mmol/l.

The amount of magnesium recommended for daily diet is 350 mg for men and 280 mg for women. Magnesi demand increases during pregnancy and lactation. Magnesi is absorbed from the gastrointestinal tract by positive transportation mechanism.

The kidney is the main organ that regulates the Magnesi balance. 3 - 5% of the metal ionization is eliminated by urine. Increasing the volume of urine (for example, in treatment with diuretics) will lead to an increase in mg ++ ionization. The decrease in the absorption of magnesium in the small intestine will cause blood magnesium to reduce elimination (

Potassium

The average K+ amount in the body is 140g (3570 mmol) in humans weighing 70 kg. The total amount of K+ in women is slightly lower and slightly decreases when high age. 2% of the total K+ amount of the body exists outside the cell.

The optimal amount of potassium that the body receives daily is 3 - 4 g (75 - 100 mmol). The kidneys are the main excretion of potassium, with about 90% of potassium excreted daily. The remaining 10% is eliminated through the gastrointestinal tract.

Therefore, in the long run, the kidneys are responsible for maintaining the home's home home balance as well as maintaining serum potassium concentration. In the short term, serum potassium concentration can be regulated by the transfer of potassium between intracellular and extracellular.

Before taking Panangin Gedeon tablets supplement potassium, Magnesi used in heart failure (50 tablets)

How to use

Take oral use.

Gastric acid can reduce the effectiveness of Panangin, so it is recommended to take whole tablets, do not chew and take after meals.

Dosage

The usual daily dose is 3 - 6 tablets/day, divided 3 times. Daily dose can increase to 9 tablets 3 times.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when using overdose? In the case of overdose, the level of potassium and blood magnesium may increase, which can cause symptoms (diarrhea, body fatigue, paresthesia, slow heartbeat, paralysis, arrhythmia, nausea, vomiting, sleep, hypotension, reflex reduction).

In case of overdose, recommendations of symptomatic treatment (intravenous calcium chloride solution (IV) 100 mg/min, hemorrhage if necessary).

What to do when you forget 1 dose? Take the next dose at the usual time.

Side Effects

When using Panangin, you may experience unwanted effects (ADR).

Higher doses can increase the number of defecation.

Instructions on how to handle ADR

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Panangin contraindicated in the following cases:

Sensitive to any ingredients of the drug.

Acute or chronic renal failure.

Addison disease (adrenal impairment).

Atrial block of III.

Cardioma (blood pressure

Be cautious when using

Note in patients with disorders related to hyperkalemia. Recommended regular monitoring of electrolytes in serum.

Children: The safety and effectiveness of Panangin in children and adolescents have not been established.

The ability to drive and operate machinery

Panangin does not affect the ability to drive and operate the machine.

Pregnancy

There is no fact of Panangin's dangerous effects on pregnant women.

Lactation period

There is no fact of Panangin's dangerous effects on nursing women.

Drug interaction

There is no study on drug interaction with Panangin. Based on literature, potassium and magnesi can interact with some drugs.

tetracyclin oral, iron salts and sodium flourid inhibit the absorption of Panangin. The distance between the use of the drug between Panangin and these drugs should be left apart at least 3 hours apart.

When using simultaneously Panangin with potassium and/or Angiotensin (ACEI), Beta, cyclosporin, cyclosporin, heparin and nonsteroidal anti -inflammatory drugs can lead to hyperboly.

Storage

Store in a dry place, at a temperature below 30 ° C.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.