Paracetamol Imex 325mg Paracetamol Reducing headache, toothache, muscle aches (10 blisters x 10 tablets)

Dosage form Tablet
Specifications Box of 10 blisters x 10 tablets
Ingredient Acetaminophen
Indication Sore throat, sinusitis, fever, headache, body aches, teething
Contraindication Anemia

Ingredient

Composition information	Content
Acetaminophen	325mg

Uses

Indications

Paracetamol 325mg drugs are indicated in the following cases:

reduce headache, toothache, muscle aches, dysmenorrhea, rheumatism and fever.

pharmacokinetics

No information.

Before taking Paracetamol Imex 325mg Paracetamol Reducing headache, toothache, muscle aches (10 blisters x 10 tablets)

How to use

oral drugs. Drink whole tablets with a little water.

Dosage

Adults and children over 11 years old

Take 325mg - 650mg/time, every 4-6 hours of drinking. Do not drink more than 4g/day.

Children from 6 to 11 years old

Take 10 - 15mg/kg/time.

The dose of paracetamol depends on the age and body weight

weight age Dosage

21.8 - 27.2kg

6 - 8 years old

320mg 9 - 10 years old 400mg/time

To minimize the risk of overdose, do not give children more than 5 paracetamol doses to reduce pain or reduce fever within 24 hours, unless the physician is instructed.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms

Paracetamol poisoning may be due to a single -dose, or due to a large dose, or for long -term medication. Liver necrosis depends on the dose is the most serious toxic effect due to overdose and can be fatal.

Nausea, vomiting, abdominal pain usually occur within 2-3 hours after taking the poison of the drug. Methemoglobin - Blood, leading to purple blue, mucosal and nails are a sign of acute poisoning P -aminophenol. Children tend to create methemoglobin easier than adults after taking paracetamol.

Clinical signs of liver damage become clearly within 2-4 days after taking toxic doses. Aminotransferase plasma increases (sometimes rising) and the concentration of bilirubin in plasma can also increase, when the liver damage spreads, the long prothrombin time. Maybe 10% of patients with untreated poisoning have serious liver damage, out of which 10% - 20% die from liver failure.

Acute renal failure also occurs in some patients. The liver biopsy detects that the central necrosis of the urine except the area around the portal vein. In cases of non -death, liver lesions recover after weeks or months.

How to handle

Early diagnosis is important in the treatment of paracetamol overdose. Gastric lavage is needed in any case, preferably within 4 hours after drinking. The main detoxification is the use of sulfhydryl compounds, which must be used immediately if less than 36 hours after taking paracetamol.

Treatment with N - Acetylcystein is more effective when giving the drug for less than 10 hours after taking paracetamol. Also can use activated carbon or saline because they have the ability to reduce paracetamol absorption.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Paracetamol Imex 325mg, you may experience unwanted effects (ADR).

Skin rods and other allergic reactions occur occasionally, usually erythema or urticaria, but sometimes worse and may be accompanied by drugs and mucosal lesions.

Patients with rare salicylate sensitive to paracetamol and related drugs. In a few individual cases, Paracetamol has caused neutropenia, thrombocytopenia and all bloody hematoma.

Uncommon: skin rash, nausea, vomiting, hematopoietic disorders (neutropenia, all bloody hemoglobin, leukopenia), anemia, kidney disease, kidney toxicity when abused for a long time.

Rare: Hypersensitivity reaction.

Instructions on how to handle ADR

Notice immediately to the doctor or pharmacist the harmful reactions encountered when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Paracetamol Imex 325mg contraindicated drug in the following cases:

Sensitive to paracetamol.

Patients with many times anemia.

heart disease, lung disease, liver failure, kidney failure.

Lack of enzymes G - 6 - P - D.

Caution when using

Paracetamol is relatively non -toxic to the dose of treatment. Sometimes there are skin reactions including itchy and urticaria, other sensitive reactions including larynx edema, angioedema and anaphylactic reactions that may rarely occur.

Ophthalmology, leukopenia and all bloody hemoglobin have occurred with the use of P - Aminophenol derivatives, especially when used for large doses. Neutral leukopenia and thrombocytopenic hemorrhage occur when using paracetamol. Rarely loss of granulocytes in patients using paracetamol.

Must use paracetamol carefully in patients with anemia before, because purple blue may not show clearly, although there are dangerous high concentrations of methemoglobin in the blood.

Drinking plenty of alcohol can cause toxicity to the liver of paracetamol, should avoid or limit drinking alcohol.

Use carefully with people with impaired liver or kidney function.

Not used with any drugs containing paracetamol.

Do not use paracetamol to treat pain relief for more than 10 days in adults, more than 5 days in children and more than 3 days to reduce high fever except for a doctor's prescription.

Doctors need to warn patients on signs of serious skin reactions such as: Stevens - Johnson syndrome (SJS), Poisoned Skin necrotic syndrome (Ten) or Lyell syndrome, acute overseas pustular syndrome (AGEP).

The drug contains FDC Yellow No.6 color excipients, so patients with allergies need to be cautious when taking this drug.

The ability to drive and operate machinery

The drug does not affect the ability to drive and operate machinery.

Pregnancy

has not determined the safety of paracetamol used during pregnancy related to unwanted effects that may be available to pregnancy development. Therefore, Paracetamol should only be used in pregnant women.

Breastfeeding period

Research in mothers using paracetamol after breastfeeding does not see unwanted effect in breastfeeding.

Medicinal interaction

Interaction of drugs

Long -doses of high -dose Paracetamol increases the anticoagulant effects of cooumarin and indoors. This effect seems to be small or not clinically important.

Need to pay attention to the likelihood of serious antipyretics in patients with phenothiazine and cooling therapy.

Alcohol, anti -convulsions (phenytoin, barbiturat, carbamazepin), isoniazid will increase the risk of paracetamol toxic to the liver.

Tyeum of drugs

Due to the absence of studies on the correlation of the drug, not mixing this drug with other drugs.

Storage

Not more than 30 ° C, avoid moisture and light.

Other drugs

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