Parokey 20mg Davipharm tablet treatment for depression, rape obsession (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Paroxetine

Ingredient

Composition information	Content
Paroxetine	20mg

Uses

Indications

Parokey 20mg drugs are indicated in the following cases:

Depression.

Panic disorders. Serotonin recovery inhibitors (SSRI) in the previous synap of serotoninergic nerve cells, increasing serotonin levels to the later synap, thereby improving depression symptoms in depression patients.

Like antidepressants and selective inhibitors of Serotonin reabsorption (Fluoxetine, Sertraline, Citalopram, Fluvoxamine), Paroxetine has the effect of rapidly increasing serotonin levels at the Synap slot of Serotoninergic Neuromus cells but the effectiveness of improving the symptoms of depressed clinical symptoms on patients is very slow, usually from 3 - 5 weeks Can be relieved when used with this medicine.

pharmacokinetic

absorption

Paroxetine is absorbed slowly but completely in the digestive tract after drinking and reaching the maximum concentration after 5 hours.

Food does not significantly affect the absorption process of the drug. Pharmacokinetics are not linear when increasing the dose. Stable concentration across the body is achieved in 7-14 days after starting treatment with instant release drugs or controlled and pharmacokinetic release does not change when long -term treatment.

Distribution

Paroxetine is widely distributed into the body tissue, which can be through the brain blood, milk and high bonds with plasma proteins, approximately 95%. The distribution volume is very fluctuated, although it has not been identified in humans, but in animals is about 3–28 l/kg.

There is no correlation between paroxetine concentration in plasma and clinical effects (therapeutic effects and unwanted effects).

Small amount of distribution of breast milk and fetuses in animal tests.

Metabolism, excretion

The drug is strongly metabolized in the liver by the enzyme CYP2D6 in the form of oxidation and methylation, then this metabolite combines with glucuronic acid to eliminate feces (about 36%) and urine (62%). A small part of 2% paroxetine does not change excretion in the urine and

Before taking Parokey 20mg Davipharm tablet treatment for depression, rape obsession (3 blisters x 10 tablets)

How to use

Parokey 20mg oral Parokey medicine. Take the whole Parokey tablet 20mg, 1 time/day in the morning with food.

Dosage

Types of depression, disorders

Types of depression, severe depression, reaction depression and anxiety: 20mg/day, gradually increasing every 10mg to 50mg/day.

Resigning disorders of murder: 40mg/day, should start 20mg, increasing each week to 10mg to 60mg/day.

Panic disorders: 40mg/day, should start 10mg, increase per week to 10mg, up to 50mg/day. Stop the drug slowly.

liver failure, kidney failure

severe renal failure (CLCR

Stress disorder after injury

Starting dose: 20mg oral once a day, with or without food, usually in the morning.

Maintenance dose: 20 - 50mg orally once a day, with or without food, usually in the morning.

Dosage changes: The dose may increase by 10mg daily for at least a week.

postmenopausal symptoms

only approve paroxetine such as Brisdelle (R): Treatment of symptoms of average vascular to serious to menopause. Take 7.5mg once a day before going to bed with or without food.

Elderly people

Starting 20mg/day, increasing gradually every 10mg, a maximum dose of 40mg/day.

Children

Not recommended.

What to do when using overdose?

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Parokey 20mg, you may experience unwanted effects (ADR).

Nausea, drowsiness, sweat, muscle tremor, weakness, dry mouth, insomnia, sexual failure. Rash.

less common

Foreign tower reaction.

Rare

Hyper enzyme, hypoglycatry blood.

Notify the doctor with unwanted effects when using the drug.

Warnings

contraindicated

Parokey drug 20mg contraindicated in the following cases:

Case of sensitivity to the ingredients of the drug.

Caution when using

with patients with cardiovascular disease, epilepsy, and haunting history.

Stop drugs when there are seizures.

Report any new problems or symptoms to the doctor, such as worsening: mood or behavior of changes, anxiety, panic, difficulty sleeping or if you feel hasty, irritant, agitated, hostile, aggressive, restless, physically (more mentally or physically), more depressed, or have thoughts about suicidal or hurt yourself.

Drug interaction

Use 2 weeks after finishing treatment with imao and vice versa.

Let the doctor know about all the drugs used and the beginning or stop use during treatment with paroxetine, especially:

Atomoxetine, Cimetidine (Tagamet), Metoprolol, Procyclidine, St. John, tamoxifen. tramadol.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

Other drugs

Disclaimer

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