PECALDEX NADYPHAR drink solution for children (18 tubes)

Dosage form Oral solution
Specifications 18 tube box
Ingredient Vitamin PP, vitamin D2, calcium gluconate, calcium glucoheptonate, vitamin C
Indication Lack of calcium, slow growth
Contraindication Kidney stones, hyper calcium, hyper calcium, cardiovascular disease, drug allergy, osteoporosis

Ingredient

Composition information	Content
Vitamin PP	0.35g
Vitamin D2	0.15g
Calcium gluconate	0.025g
Calcium glucoheptonate	0.025g
Vitamin C

Uses

Indications:

The drug is used to supplement calcium in the case of lack of calcium , children grow slowly.

Pharmacokic

calcium gluconate, calcium glucoheptonate: is an easy -to -absorb organic calcium. Oral calcium is used to treat chronic blood calcium and calcium deficiency. Lack of calcium when daily diet provides incomplete calcium, especially young women, the elderly, women before and after menopause and teenagers.

Due to increased calcium demand, children and women are the highest risk, children when calcium deficiency will grow slowly, rickets, adults with bone puree.

Vitamin C (ascorbic acid): It is necessary for collagen formation to heal wounds. Participate in some oxidation - reduction, metabolic reactions of the body. Participate in immune functions, in resistance to infections, preserve the integrity of blood vessels and in cell respiration.

Vitamin PP (nicotinamid):

In nicotinamid body performs function after converting into nicotinamid adenin dinucleotid (NAD) or Nicotinamid adenin Dinucleotid phosphate (NADP). Chemical - reducing for cell respiration, glycogen resolution and lipid metabolism.

Vitamin D2:

Often used to treat rickets, bone foam, bone puree or parathyroidism. The main biological function of vitamin D2 is to maintain normal calcium and phosphorus concentrations in plasma by increasing the effectiveness of the absorption of minerals from the diet in the small intestine and increasing the mobilization of calcium and phosphorus from bones and blood. The combination of vitamin D2 with a mixture of calcium has the effect of increasing calcium absorption. The amount of calcium is eliminated in urine is about 20%, about 80% in stool (including calcium is not absorbed and calcium is secreted through bile, pancreatic fluid).

Vitamin C (ascorbic acid):

Vitamin C is easily absorbed after drinking. Absorption decreases in people with diarrhea or stomach - intestinal disease. The normal vitamin C level in plasma is about 10 - 20 micrograms/ml. Vitamin C is widely distributed in body tissues. About 25% of vitamin C in plasma combined with protein. A little vitamin C metabolizes into non-active compounds including ascorbic acid-2-sulfate and oxalic acid excreted in urine. The amount of vitamin C exceeding the body needs (over 200mg) is quickly eliminated into the urine in the form of unchanged.

After drinking, Vitamin PP is quickly absorbed through the gastrointestinal tract, widely distributed into the body tissue and breast milk. Vitamin PP is metabolized in the liver into n-methylnicotinamid, 2-pyridon, 4-pyridon derivatives and forming nicotinuric. With the usual dose, only a small amount of vitamin PP excreted into the urine in the form of unchanged. However, with large doses, the amount of excretion in the form of unchanged will increase.

Vitamin D2:

is absorbed through the gastrointestinal tract from the small intestine. Necessary bile for absorption of vitamin D in the intestine. Vitamin D is concentrated in microorganisms, and is absorbed in the lymphatic system; Approximately 80% of vitamin D orally absorbed by this mechanism. The half-life in the plasma of Vitamin D is 19-25 hours but the drug has been stored for a long time in adipose tissue. These substances continue to be hydroxy in the kidneys to form active metabolites.

Vitamin D and its metabolites are excluded mainly through bile and feces, only a small amount appears in the urine. Some vitamin D can be secreted into milk.

Before taking PECALDEX NADYPHAR drink solution for children (18 tubes)

How to use

Take oral use.

Dosage

According to the instructions of the physician, average:

Adults: 2 pipes 5ml, 3 times a day. Drink in the morning, afternoon and afternoon.

Children: 2 tubes 5ml, 1 time, in the morning.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

Calcium: Common Hypotension (dizziness), peripheral vessels, constipation, flatulence, nausea, vomiting, red skin, rash.

Vitamin C: Increased oxalate - urinary, nausea, vomiting, heartburn, abdominal spasms, fatigue, flushing, headache , insomnia and drowsiness have occurred. After taking the dose of 1g daily or larger, diarrhea may occur.

Vitamin D:

The vitamin D can occur when treated with high or prolonged doses or when increased in response to normal doses of vitamin D will lead to clinical manifestations of calcium metabolic disorders. Some children may increase the reaction to a small amount of vitamin D. In adults, vitamin D can be used by an overdose of vitamin D in the case of a parathyroidistic minority or prefer vitamin D in a high doses. Poisoning may also occur after the wrong dose of adult vitamin D. Normally, people with normal armor function and normal sensitivity with vitamin D continuously drink 50,000 units of Vitamin D/day or more daily, may be contaminated with vitamin D. Vitamin D is especially dangerous for those who are using digitalis, because the toxicity of cardiac glycosides increases when there is increased calcium of blood calcium. Hypercalcemia has vitamin D intense due to the very high blood concentration of 25-OHD, and the concentration of PTH and calcitriol in plasma are reduced.

Common: weak, tired, sleep, headache. Anorexia, dry mouth, metal flavor, nausea, vomiting, abdominal cramps, constipation , diarrhea, dizziness, tinnitus, loss of air conditioning, foreign rash, reduced muscle tone, muscle pain, bone pain and irritability.

Uncommon: urinary - genital: sex reduction, kidney calcium infection (leading to multi -urinary, thirsty urine, much thirst, reducing the proportion of urine, proteinuria), runny nose, itching, osteoporosis in adults, reducing body development in children, weight loss, anemia, calcification conjunctivitis, fear of pancreatitis, pancreatitis. rare: hypertension, arrhythmia. On metabolic, can increase calcium, urinary phosphate, albuminuria, urinary nitrogen, serum cholesterol.

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindications:

Vitamin D or any other ingredient in the drug, hypercalcemia, hypercalcium urine, calcium stones. Verification in cardiac recovery, heart disease, kidney disease, malignant tumor destroying bones, osteoporosis due to immobile, patients are using digitalis (because of the risk of digitalis poisoning).

Caution when using

Patients with kidney stones, urinary stones.

Be cautious when using other preparations containing vitamin D2, calcium.

The ability to drive and operate machinery

does not affect.

pregnancy and lactation

Use according to the dose and recommendations.

Vitamin C passes through the placenta. If you use vitamin C according to normal needs, there is no problem on people. However, taking large amounts of vitamin C during pregnancy can increase the need for vitamin C and lead to scorbut disease in infants.

Vitamin C is distributed in breast milk. Breastfeeding people use vitamin C according to normal needs, there has not been a problem that happens to babies.

Drug interaction

When using simultaneously pecaldex with:

Iron -containing drugs: Increasing iron absorption through stomach - intestines.

Fluphenazin: Reducing Fluphenazin concentration in plasma.

aspirin: Increases the secretion of vitamin C and reduces aspirin secretion in urine.

Thiazids, Clopamid, Ciprofloxacin, Clothalidon, anti -convulsions: inhibit the excretion of calcium through the kidneys.

Tetracyclin: reduces the absorption of tetracyclin. glycosid digitalis: Increases the toxicity of the hearts of glycosides digitalis.

Should take about 3 hours away from other drugs.

Storage

Leave a cool dry place, avoid light, temperature below 30⁰C.

Other drugs

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