PECALDEX NADYPHAR drink solution for children to grow slowly (1 blister x 10 tubes x 10ml)

Dosage form Solution
Specifications Box of 1 blister x 10 tubes x 10ml
Ingredient Vitamin PP, vitamin D2, calcium gluconate, calcium glucoheptonate, vitamin C

Ingredient

Composition information	Content
Vitamin PP	0.05g
Vitamin D2	0.05mg
Calcium gluconate	0.3g
Calcium glucoheptonate	0.7g
Vitamin C	0.1g

Uses

Indications:

The drug is used to supplement calcium in case of calcium deficiency, children grow slowly.

Pharmacokology

calcium gluconate, calcium glucoheptonate:

is an easy -to -absorb organic calcium. Oral calcium is used to treat chronic blood calcium and calcium deficiency.

Lack of calcium when daily diet provides incomplete calcium, especially young women, the elderly, women before and after menopause, teenagers.

Due to increasing calcium demand, children and women are the highest risk, children when calcium deficiency will grow slowly, rickets, adults with bone puree.

Vitamin C (ascorbic acid):

It is necessary for the formation of collagen to heal wounds. Participate in some oxidation - reduction, metabolic reactions of the body.

Participate in immune functions, in resistance to infections, preserve the integrity of blood vessels and in cell respiration.

Vitamin PP (Nicotinamid):

In nicotinamid body performs function after converting to Nicotinamid Adenin Dinucleotid (NAD) or Nicotinamid Adenin Dinucleotid phosphate (NADP).

NAD and NADP plays a very important role in metabolic, as a coenzyme acting as hydrogen transport molecules, catalysts oxidation and reduction reactions needed for cell respiration, glycogen resolution and lipid metabolism.

Vitamin D2:

Often used to treat rickets, bone porous, bone puree or parathyroidism.

The main biological function of vitamin D2 is to maintain normal calcium and phosphorus concentration in plasma by increasing the effectiveness of the absorption of minerals from the diet in the small intestine and increasing the mobilization of calcium and phosphorus from bone and blood.

Ergocalciferol's activities may have a negative response effect on the formation of parathyroid hormones (PTH). The combination of vitamin D2 with a mixture of calcium has the effect of increasing calcium absorption.

pharmacokinetics

calcium: about 30% of calcium is absorbed in the digestive tract. The amount of calcium is eliminated in urine is about 20%, about 80% in stool (including calcium is not absorbed and calcium is secreted through bile, pancreatic fluid).

Vitamin C (ascorbic acid):

Vitamin C is easily absorbed after drinking. Absorption decreases in people with diarrhea or stomach - intestinal disease. Normal vitamin C concentration in plasma is about 10 - 20 micrograms/ml.

Storage all vitamin C in the body about 1.5g with about 30 - 45 mg is rotated daily. Vitamin C is widely distributed in body tissues. About 25% of vitamin C in plasma combined with protein.

Vitamin C is oxidized to Dehydroorscorbic acid. A little vitamin C metabolizes into non-active compounds including ascorbic acid-2-sulfate and oxalic acid excreted in urine. The amount of vitamin C exceeding the body needs (over 200mg) is quickly excreted into urine in the form of unchanged.

Vitamin PP (Nicotinamid):

After drinking, vitamin PP is quickly absorbed through the gastrointestinal tract, widely distributed into the body tissue and breast milk.

The sale time of vitamin PP is about 45 minutes. Vitamin PP is metabolized in the liver into n-methylnicotinamid, 2-Pyridon, 4-Pyridon derivatives and forming nicotinuric. Vitamin PP is eliminated by sub -road.

With the usual dose, only a small amount of vitamin PP excreted into the urine in the form of unchanged. However, with large doses, the amount of excretion in the form of unchanged will increase.

Vitamin D2:

is absorbed through the gastrointestinal tract from the small intestine. Necessary bile for absorption of vitamin D in the intestine. Vitamin D is concentrated in microorganisms, and is absorbed in the lymphatic system; Approximately 80% of vitamin D orally absorbed by this mechanism.

Vitamin D and its metabolites rotate in the blood associated with specific alpha globulin. The half -life in the plasma of Vitamin D is 19-25 hours but the drug is stored for a long time in fat tissue.

colecalciferol and ergocalciferol are hydroxylation in the liver forming 25-hydroxy-canCalciferol and 25-hydroxyergocalciferol respectively. These substances continue to be hydroxy in the kidneys to form active metabolites.

The liver is the place where Vitamin D transfers to 25-oHD, which is linked to protein and circulation in the blood.

Vitamin D and its metabolites are excluded mainly through bile and feces, only a small amount appears in the urine. Some vitamin D can be secreted into milk.

Before taking PECALDEX NADYPHAR drink solution for children to grow slowly (1 blister x 10 tubes x 10ml)

How to use

Take oral use.

Dosage

According to the instructions of the physician, average:

Adults: Each time drink 1 tube 10ml or 2 tubes 5ml, 3 times a day. Drink in the morning, afternoon and afternoon.

Children: Each time drinking 1 tube 5ml, 2 times a day, drink in the morning and at noon or drink 1 tube 10ml, once a day, in the morning.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

Calcium: Common hypotension (dizziness), peripheral vessels, constipation, flatulence, nausea, vomiting, skin redness, rash.

Vitamin C: Increase oxalate - urinary, nausea, vomiting, heartburn, abdominal spasms, fatigue, redness, headache, insomnia and drowsiness have occurred. After taking the dose of 1g daily or larger, diarrhea may occur.

Vitamin D:

The vitamin D can occur when treated with high or prolonged doses or when increased in response to normal doses of vitamin D will lead to clinical manifestations of calcium metabolic disorders. Some children can increase the reaction with a small amount of vitamin D. Poisoning may also occur after taking the wrong dose of vitamin D of adults. Normally, people with normal and normal thyroid thyroid function with vitamin D continuously drink 50,000 units of vitamin D/day or more daily, may be contaminated with vitamin D. Vitamin D is especially dangerous for those who are using digitalis, because the toxicity of cardiac glycosides increases when there is hypercalcemia.

Signs and initial symptoms of Vitamin D poisoning are signs and symptoms of hypercalcemia. Hypercalcemia has vitamin D strength due to simply blood concentration of 25-OHD very high, while the concentration of PTH and calcitriol in plasma decreases.

Hypercalcemia and toxicity of vitamin D have a number of side effects:

Common: weak, tired, sleep, headache. Anorexia, dry mouth, metal flavor, nausea, vomiting, cramps in the abdomen, constipation, diarrhea, dizziness, tinnitus, loss of air -conditioning, foreign rash, reduced muscle tone, muscle pain, bone pain and irritation.

Uncommon: urinary - genital: Sexual reduction, kidney calcium infection (leading to multiple urethra, urination, thirsty, reducing the proportion of urine, proteinuria), runny nose, itching, osteoporosis in adults, reducing body development in children, weight loss, anemia, calcification conjunctivitis, fear of light, calcification in many places, pancreatitis. rare: hypertension, arrhythmia. On metabolic, can increase calcium, urinary phosphate, albuminuria, urinary nitrogen, serum cholesterol.

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindications:

Vitamin D or any other ingredient in the drug, hypercalcemia, hypercalcium urine, calcium stones. Verification in cardiac recovery, heart disease, kidney disease, malignant tumor destroying bones, osteoporosis due to immobile, patients are using digitalis (because of the risk of digitalis poisoning).

Caution when using

Patients with kidney stones, urinary stones.

Be cautious when using other preparations containing vitamin D2, calcium.

The ability to drive and operate machinery

does not affect.

pregnancy and lactation

Use according to the dose and recommendations.

Vitamin C passes through the placenta. If you use vitamin C according to normal needs, there is no problem on people. However, taking large amounts of vitamin C during pregnancy can increase the need for vitamin C and lead to scorbut disease in infants.

Vitamin C is distributed in breast milk. Breastfeeding people use vitamin C according to normal needs, there has not been a problem that happens to babies.

Drug interaction

When using simultaneously pecaldex with:

Iron -containing drugs: Increasing iron absorption through stomach - intestines

Fluphenazin: Reducing Fluphenazin concentration in plasma. Aspirin: Increases the excretion of vitamin C and reduces aspirin excretion in urine

Thiazids, Clopamid, Ciprofloxacin, Clothalidon, anti -convulsions: inhibit the excretion of calcium through the kidneys.

Tetracyclin: reduces the absorption of tetracyclin. glycosid digitalis: Increases the toxicity of the hearts of glycosides digitalis.

Should take about 3 hours away from other drugs.

Storage

Leave a cool dry place, avoid light, temperature below 30⁰C.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.