Penicilin V Potassium 1,000,000 I.U Vidipha Treatment and prevent infections (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Penicillin v

Ingredient

Composition information	Content
Penicillin v	1,000,000iu

Uses

Indications

Penicilin v potassium 1,000,000 I.U is indicated in the following cases:

Treatment or prevent infections caused by sensitive bacteria, especially streptococcus, currently penicillin V is indicated in mild to moderate infections such as:

Upper respiratory infections, sore throat - tonsils, otitis media .

Infections in the mouth, throat.

Mild pneumonia caused by pneumococcus.

Skin infections and soft tissue.

Room rheumatism recurrent level.

Treatment should be based on antibiotic test results and clinical response.

Pharmacokinus

penicillin v potassium 1000,000 is a preparation of sustainable penicillin V with gastric acid should be used orally.

Penicilin V has a bactericidal effect by inhibiting the synthesis of bacterial cell shells. However, this effect is reduced by penicilinase and other beta-lactamase.

Penicilin V works well on common gram -positive bacteria such as beta -soluble streptococcus, Viridans streptococcus, pneumococcal, staphylococcus (except for penicillinase). The minimum concentration of Australia is usually in the range of 0.01 - 0.1 mg/liter. Penicilin V is considered the first choice for most respiratory, skin or soft tissue infections.

With the Haemophilus Influenzae strain without beta - lactamase, the minimum concentration inhibits' usually about 2.6 mg/iodine. According to the high doses of treatment regimen, 2 times/day, the drug may reach concentrations in tissues and blood higher than the above level.

The drug has little effect on some bacteria, especially gram -negative bacteria.

Dynamic pharmacokinetics

penicillin V is not ineffective by gastric acid and absorbed through the gastrointestinal tract better than benzylpenicilin after drinking. The drug is absorbed quickly, about 60% of oral dose. Calcium salt and potassium salts are better absorbed than acid form. Plasma peak concentration is about 3 - 5 µg/ml achieved for 30-60 minutes after taking the dose of 800 000 I.U. The absorption of the drug is reduced when used with food or after meals.

Half a life of plasma is about 30-60 minutes and can increase to 4 hours in case of severe renal failure. About 80% of the drug is associated with protein. Penicilin V is metabolized and quickly excreted through urine mainly by excretion in the renal tubules. The drug is metabolized in the liver, one of the metabolites has been identified as peniciloic acid. The drug is rapidly excreted through the urine in the form of constant and metabolic form. Only a small amount of excretion through the bile line.

Before taking Penicilin V Potassium 1,000,000 I.U Vidipha Treatment and prevent infections (10 blisters x 10 tablets)

How to use

Should take the drug 30 minutes before or 2 hours after meals.

Dosage

Treatment of pneumococcus pneumonia, tonsillitis, sore throat by strepfococcus group A or other bacterial infections caused by the beta blood -soluble streptococcus

Adults and children over 12 years: 250 - 500 mg (400,000 I.U - 800,000 I.U), every 6 - 8 hours.

Children under 12 years old: 25 - 50 mg (40,000 I.U - 80,000 I.U)/kg/day, divided into 3-4 times; Middle otitis: 25 mg (40,000 I.U)/kg/time, 2-3 times/day. The treatment time is usually 10 days.

Adjustable dose for people with severe kidney failure

Creatinine clearance is over 10 ml/minute: 250 - 500mg (400,000 - 800.0001.U), every 6 hours.

Creatinine clearance below 10ml/minute: 250mg (400.0001.U), every 6 hours. To prevent relapse of rheumatism, the dose of 250mg (400.0001.U) can be used, 2 times/day.

Influenzae infection (like treating ear infections in children in general)

penicillin v 50mg (80,000 I.U)/kg body weight/24 hours, divided into 2 times. Treatment for at least 10 days.

If not, for amoxicilin and clavulanic acid or a oral cephalosporin or trimethoprim + sulfamethoxazol. Macrolid antibiotics are not indicated in case of ineffective penicillin treatment.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that you should not use double the dose to compensate for the forgotten dose.

Side Effects

When using Penicilin V Potassium 1,000,000 I.U, you may experience unwanted effects (ADR).

Common

Gastrointestinal tract: diarrhea , nausea.

Skin: BOARD.

Less

Blood: Eosin hypernagus.

skin: urticaria.

Rare

Body: Anaphylaxis .

Digestive: diarrhea is related to Clostridium difficile (much less common than when using ampicillin and amoxicillin).

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Penicillin voic Potassium 1,000,000 I.U Contraindications in the following cases:

Hypersensitivity to antibiotics of cephalosporin groups.

Caution when using

People with allergies to cephalosporin antibiotics.

People with a history of allergies or asthma.

Severe respiratory infections (such as severe pneumonia) cannot be treated with penicillin v.

Note: This drug is only used by a doctor.

Do not use the drug if:

The pills are discolored, cracked.

The blister is torn.

Stop taking the medication immediately and notify the doctor when experiencing allergy symptoms.

Read the instructions carefully before use. If you need more information, please consult your doctor.

to be out of reach of children.

Do not use overdue drugs used on the label.

The ability to drive and operate machinery

There is no document.

Pregnancy

There is no risk of harm to pregnant women.

Breastfeeding period

Penicilin V is secreted into breast milk, although not harmful but can cause an allergic reaction for breastfeeding.

Drug interaction

absorption of penicillin V is reduced by plastic gum.

Neomycin oral form can reduce the absorption of V -V -50%. Perhaps due to Neomycin causes recovery reduction syndrome.

Storage

Store in a dry place, avoid light, the temperature does not exceed 30 ° C.

Other drugs

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