Penicillin V 400000 IU Mekophar treat infections (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Penicillin

Ingredient

Composition information	Content
Penicillin	4000000iu

Uses

Indications

Penicillin v 400,000 IU is indicated in the following cases:

Treatment of infections caused by sensitive bacteria, especially streptococcus, but only used in the treatment of mild or medium infections.

Upper respiratory tract infections, sore throat - tonsils, otitis media.

Infections in the mouth, throat.

Skin infections and soft tissue.

Room recurrent rheumatism.

Mild pneumonia caused by pneumococcus.

Pharmacy

phenoxylpenicilin (penicillin v) is an antibiotic belonging to the Beta-Lactam family of penicillin, penicillin v sustainable with gastric acid should be used orally, have bactericidal effects by inhibiting the synthesis of bacteria.

Penicilin V has a good effect on common gram -positive bacteria such as beta -soluble streptococcus, Viridans streptococcus and pneumococcal. The drug also works with Staphylococcus (except for the seminarian penicillinase). Penicilin V has little effect on some bacteria, especially gram -negative bacteria.

pharmacokinetics

penicillin V is not ineffective by gastric acid, good absorption through the digestive tract after drinking. The drug is absorbed quickly, about 60% of oral dose. The absorption of the drug is reduced when used with food or after meals.

Selling time is about 30-60 minutes. About 80% of the drug dose associated with protein.

Penicilin V is metabolized in the liver, one of the metabolites has been identified as peniciloic acid. The drug is rapidly excreted through the urine in the form of constant and metabolic form. Only a small amount of excretion through the bile line.

Before taking Penicillin V 400000 IU Mekophar treat infections (10 blisters x 10 tablets)

How to use

Take oral use.

Take the medicine 30 minutes before eating or 2 hours after meals.

Dosage

Treatment of tonsillitis, sore throat by streptococcus group A or other bacterial infections due to streptococcus of Beta blood -soluble streptococcus

Adults and children over 12 years: Drink 400,000 - 800,000 IU/time, 3-4 times/day.

Children under 12 years old: Take 40,000 - 80,000 IU/kg/day, divided into 3-4 times.

Middle otitis media

40,000 IU/kg/time, 2-3 times/day.

To prevent relapse of rheumatism

Children from 6 - 12 years old: drink 400,000 IU/time, drink twice a day.

Adults: Take 800,000 IU/time, drink 2 times a day.

Time of treatment is about 10 days.

Adjust the dose when kidney failure

Creatinine clearance

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Overdose

Nausea, vomiting, diarrhea.

Handling

There is no specific antidote.

Treatment of symptoms and support. However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that you should not use double the dose to compensate for the forgotten dose.

Side Effects

When using Penicillin V 400,000 IU, you may experience unwanted effects (ADR).

Common, (ADR> 1/100)

Digestive: Nausea, diarrhea.

DA: BOARD.

Uncommon, (1/1000

Blood: Eosin hypernagus.

skin: urticaria.

Rare, (ADR

Body: Anaphylaxis.

digestion: diarrhea is related to Clostridium difficile.

Instructions on how to handle ADR

Stop the drug if the patient has diarrhea or an allergic reaction.

Notice immediately to the doctor or pharmacist the harmful reactions encountered when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Penicillin v 400,000 IU contraindications in cases where patients have a history of hypersensitivity to antibiotics of penicillin, cephalosporin or any component of the drug.

Be cautious when using

There is a cross allergy to cephalosporin. In case of all allergies, cephalosporin, no penicillin.

Patients with a history of allergies or asthma.

Oral penicillin is not indicated in patients with serious illness or gastrointestinal problems such as prolonged nausea, taste spasms, increased intestinal motility, diarrhea, due to reduced drug absorption.

Streptococcus infection should be treated for at least 10 days, after treatment, culture to determine bactericidal effect.

In patients with long -term treatment with penicillin V, a full blood formula test is needed as well as monitoring liver and kidney function.

Long -term treatment can develop resistance strains such as Pseudomonas, Candida. If superinfection occurs, appropriate measures should be taken.

Precautions when using drugs for patients with a history of colitis related to antibiotics.

Preparations containing potassium, which can be harmful to people with a low -potassium diet and can cause abdominal pain, diarrhea, hyperkalemia. High doses should be used carefully in patients who use additional potassium or potassium -saving diuretic drugs.

In people with impaired renal function, a safe dose should be lower than the usual dosage.

During treatment with penicillin V, it may cause false positive when doing non -enzyme glucose tests.

Preparations containing Tartrazin colored excipients, Sunset Yellow color can cause allergic reactions.

The ability to drive and operate machinery

has not recorded a adverse reaction report or no research on the effect of the drug on the ability to operate machinery.

Pregnancy

Animal research does not show the monster effect of penicillin V, penicillin V has been widely used clinically and suitable for pregnant women, which have been recorded in clinical trials. However, like other drugs, should be cautious in prescription for pregnant women.

breastfeeding period

Women who breastfeed are not contraindicated for potassium and potassium penicillin. A small amount of V -pen can be secreted into breast milk. Harmful reactions are often rare, there are 2 problems that can occur in breastfeeding:

Change of intestinal bacteria.

Impacts on children such as allergies/increased sensitivity.

Be cautious when using medication for breastfeeding women.

Drug interaction

absorption of penicillin V is reduced by plastic.

Neomycin oral form can reduce the absorption of V -V -50%. Perhaps due to Neomycin causing recovery reduction syndrome.

Do not coordinate with bactericidal antibiotics such as tetracyclin, erythromycin, chloramphenicol, sulfonamid.

Concentrated with uric acid exhaust drugs (for example: Probenecid, sulfinPyrazon) reduces penicillin excretion, leading to increased blood concentration in blood, prolonging the impact time of the drug.

penicillin V reduces methotrexate elimination, leading to the risk of increased toxicity.

Penicilin V can reduce the effectiveness of oral contraceptives. Patients should use additional methods of contraception during treatment with penicillin v.

Use a combination of penicillin v with oral anticoagulant drug that can extend prothrombin time.

Tyeum of drugs

Due to the absence of studies on the correlation of the drug, not mixing this drug with other drugs.

Storage

Store in a dry place, avoid light, the temperature does not exceed 30 ° C.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.