Pepevit 50mg Nadyphar tablets treat Pellagra (100 tablets)

Dosage form Tablet
Specifications Box of 100 capsules
Ingredient Nicotinamid
Indication Pellagra disease, lipoprotein metabolism disorders
Contraindication Hepatic failure, low blood pressure, arterial hemorrhage

Ingredient

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Composition information	Content
Nicotinamid	50mg

Uses

indications

Pepevit 50mg drug are indicated in the following cases:

Treatment of Pellagra disease. In the body of vitamin PP performs function after converting to nicotinamid adenin dinucleotid (NAD) or nicotinamid adenin dinucleotid phosphate (NADP). NAD and NADP plays a very important role in metabolism, as a coenzyme that works as hydrogen transport molecules, catalyzed the redox reactions necessary for cell respiration, glycogen resolution and lipid metabolism.

pharmacokinetics

absorption: After oral, vitamin PP is quickly absorbed through the digestive tract,

Distribution: The drug is widely distributed into the body tissue and through breast milk.

Metabolism: Vitamin PP is metabolized in the liver into n-methylnicotinamid, 2-Pyridon, 4-Pyridon derivatives and forming nicotinuric.

Elimination: The sale time of vitamin PP is about 45 minutes. Vitamin PP is eliminated by urinary tract. With the usual dose, only a small amount of vitamin PP excreted into urine formless. However, with large doses, the amount of excretion in the form of unchanged will increase.

Before taking Pepevit 50mg Nadyphar tablets treat Pellagra (100 tablets)

How to use

Pepevit 50mg medicine Used orally.

Dosage

Adults: 6-10 tablets/ day, divided into 3 times. Maximum dose of 30 tablets/ day, divided into 3-10 times.

Children: 2-6 tablets/ day, divided into 3 times.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when using overdose?

Use common measures such as vomiting, gastric lavage, symptomatic treatment and support.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not use double the prescribed dose.

Side Effects

When using pepevit 50mg , you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive: Nausea.

Other: blushing and neck, itching, burning sensation, pain or throbbing pain in the skin.

Uncommon, 1/1000

digestion: Stomach ulcer progresses, vomiting, appetite, pain when hungry, flatulence, diarrhea .

Skin: dry skin, hyperpigmentation, jaundice.

Metabolic: Hepatic failure, reducing glucose tolerance, increased sebaceous secretion, worse gout.

Other: hyperglycemia, hyperuricemia, vagus- blood vessels, headache and blurred vision, hypotension , dizziness, fast heartbeat.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Pepevit 50mg contraindicated in the following cases:

Hypersensitivity to vitamin PP.

Severe liver disease, progressive stomach ulcers.

arterial hemorrhage and severe hypotension.

Be cautious when using

When using high doses of vitamin PP should be cautious for the following cases:

History of stomach ulcers, gallbladder disease, liver disease.

Gout, gout arthritis.

Diabetes .

The ability to drive and operate machinery

The drug does not affect the ability to drive and operate machinery,

Pregnancy

is used for pregnant women.

breastfeeding period

can be used for nursing women.

Interactive drug

Do not use vitamin PP simultaneously with:

HGM-COA reducing enzyme inhibitors because of the increased risk of muscle eligibility.

Alpha-adrenergic blockers because it can lead to excessive hypotension.

drugs that are toxic to the liver and increase the toxic to the liver.

carbamazepin, because of increasing carbamazepine concentration in plasma, increases toxicity.

Storage

At a temperature not exceeding 30 ° C, in a dry place, avoiding light

Other drugs

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