Pharmaclofen 10mg Pharmascascique tablets treat skeletal spasms (100 tablets)

Dosage form Box of 100 capsules
Specifications Baclofen

Ingredient

Composition information	Content
Baclofen	10mg

Uses

Indications

Pharmaclofen is indicated in the following cases:

Treatment of spasms (excessive muscle spasms).

scattered sclerosis . Brain

Head injury. The drug has the effect of inhibiting the transmission of multi -synap reflexes in the spinal cord.

pharmacokinetic

absorption

Baclofen is absorbed quickly and almost completely through the gastrointestinal tract. After taking 1 dose (10 - 30 mg) of the peak concentration in plasma after 0.5 - 1.5 hours and AUC is proportional to the dose.

Distribution

The distribution of 0.7 l/kg, ratio attached to plasma proteins 30%. In cerebrospinal fluid, substance concentration is about 8.5 times lower in plasma.

Metabolism

Baclofen is metabolized at a small percentage. Eliminate amino to form the main metabolites-(p-chlorophenyl) -4- hydroxybutyric acid, which is no longer active.

Elimination

Semi -selling time in Baclofen's plasma is average of 3 - 4 hours, the ratio of plasma protein is about 30%.

Baclofen is eliminated mainly in the form of unprovered. Within 72 hours, about 75% of the dose was eliminated through the kidneys, of which, about 5% were metabolized.

Before taking Pharmaclofen 10mg Pharmascascique tablets treat skeletal spasms (100 tablets)

How to use

pharmaclofen 10 mg is used orally.

Dosage

Dosage depends on each individual. Should start with the lowest dose then increase the dose slowly to reach optimal response (usually from 40 - 80 mg, ie 4 - 8 pharmaclofen).

Recommended regimen:

5 mg Baclofen (½ Pharmaclofen), 3 times/day for 3 days.

10 mg baclofen (1 pharmaclofen), 3 times/day for 3 days.

15 mg Baclofen (1.5 tablets Pharmaclofen), 3 times/day for 3 days.

20 mg Baclofen (2 Pharmaclofen), 3 times/day for 3 days.

may later increase the dose but not more than 80 mg. The lowest dose should be used with optimal results. If after a period of use of the drug does not bring results, should reduce the dose slowly and then stop.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Signs and symptoms

Vomiting, reducing muscle tone, drowsiness, endocrine disorders, coma, respiratory failure, and convulsions.

Symptomatic treatment. Patients overdose need to empty the stomach by causing vomiting then gastric lavage. In the case of patients with severe renal failure and poisoning must perform the fertilizer.

Side Effects

When using Pharmaclofen you may experience unwanted effects (ADR).

Common, ADR> 1/100

The cardiovascular system: Hypotension .

Cardiovascular system: Difficulty breathing, brushing chest, chest pain, fainting. Ban.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Pharmaclofen contraindicated in the following cases:

Hypersensitivity to Baclofen or any ingredients in the drug.

Be cautious when using

Sudden remedy: The hallucinations of vision and hearing, and anxiety occur with tachycardia and sweating, insomnia and aggravating spasms. Need to reduce the drug slowly to avoid the condition of the drug.

Patients with impaired renal function: Because the drug is eliminated through the kidneys, it is necessary to reduce the dose when necessary.

Stroke: Baclofen is not effective for patients with stroke because they respond less with drugs.

Safety when using drugs for children

Special attention in patients with epilepsy or a history of convulsions, should be evaluated regularly with the condition and brain electrical diagram due to occasional convulsions and brain electrical condition of the patient with bad manifestations when treating with Baclofen.

Be cautious in patients with gastrointestinal ulcers, severe mental disorders, elderly people with brain vascular disease, patients who are taking hypertension medication.

The ability to drive and operate machinery

drugs have a sedative effect, so be careful when driving and operating machinery.

Pregnancy

Unknown the effect of Baclofen on the fetus, need to consider the benefits and risks before using the drug for this object.

Breastfeeding period

The amount of excretion in Baclofen's milk is too small to be dangerous, but it is necessary to be advised by a doctor or pharmacist before use.

Medicinal interaction

Need to notify the doctor when taking: 3 -round antidepressants, Mao inhibitors, Central neurological inhibitors, ibuprofen, antihypertensive drugs, diuretics, anti -diabetes drugs, carbidopa/levodopa, alcohol.

Storage

temperature below 30ºC.

Other drugs

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