Pharmox hard capsules 500mg Imexpharm treat infection cases (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Amoxicillin

Ingredient

Composition informationContent
Amoxicillin500mg

Uses

indications

Pharmox SA drugs are indicated in the following cases:

Treatment of infections caused by sensitive bacteria, including:

  • Upper respiratory tract infections. Coli sensitive to amoxicillin. The drug has a bactericidal effect, due to inhibition of mucopeptide biosynthesis of bacterial cell walls.

    In vitro, amoxicillin is active with the majority of Gram -negative and Gram -positive bacteria such as: bacterial streptococcus, non -penicillinase staphylococcus, H. Influenzae, Diplococcus Pneumoniae, N. Gonorrheae, E. Coli and Proteus Mirabilis. Amoxicillin is not active with penicillinase secretion, especially staphylococcus aureus, all Pseudomonas strains and most of the Klebsiella and Entobacter strains.

    Dynamic pharmacokinetics

    Amoxicillin absorbs quickly and completely through the digestive tract, the absorption is not affected by food. Amoxicillin is quickly distributed into most tissues and fluids in the body, except for brain tissue and cerebrospinal fluid but when the meninges are inflamed, the drug diffuses easily. After taking the dose of 500mg, the concentration of amoxicillin reaches about 8 - 10 micrograms/ml. Amoxicillin oral or injected evenly for the same concentrations of drugs in plasma. Amoxicillin waste time is about 61.3 minutes, longer in infants and the elderly. In people with kidney failure, the sale time of the drug is about 7-20 hours long. About 60% of the oral dosage of amoxicillin is eliminated into the urine in the form of unchanged within 6 - 8 hours.

    • Before taking Pharmox hard capsules 500mg Imexpharm treat infection cases (10 blisters x 10 tablets)

    How to use

    oral medication. Drinking before or after eating is due to the ability to absorb the drug is not affected by food.

    Dosage

    The usual dose is 250mg - 500mg/time, each time 8 hours apart.

    The content and preparation of Pharmox SA 500mg are not suitable for children (under 18 years old).

    higher dose, single dose or in short phases, used in the following cases:

  • 3G dose, repeat once after 8 hours to treat APXE around the teeth or repeat after 10 - 12 hours to treat uncomplicated urinary tract infections.
  • Preventing pericarditis in humans susceptible: The only dose 3g, 1 hour before the procedure such as tooth extraction.
  • Severe or recurrent respiratory infections: 3G dosage amoxicillin x 2 times/day.

    • For people with renal failure, the dose must be reduced according to the evaporation coefficient of creatinine:

    Creatinine clearance coefficient (ml/minute)

    Dosage

    500mg/24 hours

    500mg/12 hours

    Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

    What to do when overdose?

    Handling: Stop drug and symptomatic treatment. A sufficient amount of water and diuretics are required to minimize the risk of crystal crystals. Pay attention to water and electrolyte balance. Amoxicillin can be removed from cycle by dialysis.

    What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

    Side Effects

    When using Pharmox SA, you may experience unwanted effects (ADR).

    Common: BOD (3 - 10%) usually appear slowly, after 7 days of treatment.

    Uncommon: Nausea, vomiting, diarrhea, erythema, lumpy rash, urticaria, Stevens-Johnson syndrome.

    Rarely: ASTRATE, ACCEPTING, LEASING, ANH LOSS, Insomnia, Confusion, Change behavior and/or dizziness, Anemia, thrombocytopenia, EOSIN, EOSIN hyposopenosis, leukopenia, losing leukocytes.

    Instructions on how to handle ADR

  • Amoxicillin's undesirable reactions in the digestive tract, in the blood, are often lost when stopping treatment.
  • Rural, other forms and serum -like reactions that can be treated with antihistamine and systemic corticosteroid therapy. However, it is best to stop using amoxicilin, unless there is a doctor's opinion in special cases, life -threatening that only amoxicillin can be resolved.

    • Notify the doctor with unwanted effects when using the drug.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    contraindicated

    Pharmox SA drugs are contraindicated in the following cases:

  • Sensitive to any ingredients of the drug.

    • Patients with a history of allergies to Beta-Lactam drugs (penicillin and cephalosporin)

    Be cautious when using

    periodically check the liver and kidney function during long -term treatment.

    There may be severe hypersensitivity reactions in patients with a history of allergies to penicilin or other allergens, so it is necessary to carefully investigate the history of allergies to penicillin, cephalosporin and other allergens.

    If allergic reactions occur such as erythema, rash, anaphylaxis, Stevens - Johnson syndrome, amoxicillin must be stopped and immediately treated emergency treatment with adrenalin, oxygen breathing, intravenous corticoid therapy and ventilation, including internal trachea and stop using penicilline or cephalosporin.

    The ability to drive and operate machinery

    The drug that can cause side effects is dizzy, so it should be noted when used for train drivers and operating machinery.

    Pregnancy

    There is no scientific document to prove the safety when used for pregnant women. Therefore, you should consult a doctor and only use the drug when really necessary for this object.

    Lactation period

    Amoxicillin excreted in breast milk, so be careful when taking the drug during breastfeeding. It is best to consult a doctor before taking this medication.

    Interactive drug

    nifedipine increases amoxicillin absorption.

    When shared with alopurinol and amoxicillin will increase the ability of amoxicillin.

    Pliers like chloramphenicol, tetracyclin can limit the bactericidal effect of amoxicillin.

    Similar to other broad spectrum antibiotics, amoxicillin can reduce the effects of oral contraceptives.

    Amoxicillin can lead to false positive of the urine -looking test test by using Sulfate copper methods (Benedict's solution, Fehling's or clinitest solution).

    Penicilin reduces excretion and thus increases the toxicity of methotrexate.

    Antibiotics that make typhoid vaccine.

    SulfinPyrazone reduces the elimination of penicillin groups.

    Simultaneous use of amoxicillin and anticoagulants can extend the blood clotting time.

    Storage

    under 30 ° C, avoid moisture and light.

    Other drugs

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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