Piracetam Kabi 1g/5ml Bidiphar treatment of memory loss (2 blisters x 6 tubes x 5ml)

Dosage form Box of 2 blisters x 6 tubes x 5ml
Specifications Piracetam

Ingredient

Thành phần cho 5ml

Composition information	Content
Piracetam	1g

Uses

indications

Piracetam medicine 1 g/5 ml is indicated in the following cases:

Treatment of dizziness symptoms.

In children with treatment support for difficulty reading. As the mechanism of action. Even the definition of Hung Tri "Nootropie" is still vague.

In general, the main effects of drugs are called Hung Tri (such as Piracetam, Oxiracetam, Aniracetam, Etiracetam, Pramiracetam, Tenilsetam, Sulotidil, Tamitinol) is to improve learning and memory ability. Many of these are considered to have a stronger effect on piracetam in terms of learning and memory. It is thought that in ordinary people and functional impaired people, Piracetam directly affects the brain to increase the activity of the brain area (the brain area is involved in the mechanism of awareness, learning, memory, alertness and consciousness).

Piracetam acts on a number of neurotransmitters such as acetylcholin, noradrenalin, dopamin ... This can explain the positive effects of the drug on learning and improve the ability to perform memory tests. The drug can change neurotransmitter and contribute to improving the metabolic environment so that the neurons work well.

On experiments, Piracetam has a protective effect against metabolic disorders due to ischemia by increasing brain resistance to oxygen deficiency. Piracetam increases glucose mobilization that does not depend on oxygen supply, facilitates the pentose path and maintains energy synthesis in the brain.

Piracetam enhances the recovery rate after damage due to lack of oxygen by increasing the rotation of inorganic phosphate and reducing glucose and las acid accumulation. Under normal conditions as well as lack of oxygen, Piracetam is found to increase the amount of ATP in the brain due to increased ADP conversion to ATP; This may be a mechanism to explain some useful effects of the drug.

The impact on acetylcholin transmission (increasing the release of acetylcholin) may also contribute to the mechanism of action of the drug. The drug also works to increase the release of dopamine and this may have a good effect on the formation of memory. The drug has no effect on sleep, sedation, resuscitation, analgesic, nervous or neuron and no effect of GABA.

Piracetam reduces the ability to conclude platelets and in case of abnormal erythrocytes can cause red blood cells to restore the ability to deform and sunburn through capillaries. The drug has anti -vibration effect.

Dynamic pharmacokinetics

Biological use nearly 100%. Absorption of drugs does not change when long -term treatment. The volume of VD distribution is about 0.6 liters/kg.

Piracetam absorbed into all tissues and may be through the blood - brain, placenta barrier and the membranes used in the kidney. The drug has high concentrations in the cerebral cortex, frontal lobe, top lobe and hydraulic, cerebellum and base nucleus. Half life in plasma is 4 - 5 hours; Half life in cerebrospinal fluid is about 6 - 8 hours.

Piracetam is not attached to plasma proteins and is excreted through the kidneys in the form of intact. Piracetam clearance coefficient of the kidney in normal people is 86 ml/min, 30 hours after taking more than 95% of the drug excreted in urine. If there is a kidney failure, half a lifetime elimination increases: In patients with completely renal failure and not recovering, this time is 48 - 50 hours.

Before taking Piracetam Kabi 1g/5ml Bidiphar treatment of memory loss (2 blisters x 6 tubes x 5ml)

How to use

Intravenous, infusion or intramuscular injection.

can also be used for drinking if you have to stop using the injection form.

Dosage

The common dose is 30 - 160 mg/kg/day, depending on the indications, divided evenly twice a day or 3-4 times.

Severe cases, the dose can be increased to 12 g/day and using intravenous lines.

Alcoholic treatment:

12 g/day during the first time of alcohol.

Maintain treatment: Take 2.4 g/day.

Cognitive decline after brain injury (with dizziness or no):

initial dose is 9 - 12 g/day; The maintenance dose is 2.4 g of medicine, taken at least for at least 3 weeks.

sickle cell anemia:

180 mg/kg/day, divided equally into 4 times.

Treatment of muscle vibration:

7.2 g/day, divided into 2-3 times. Depending on the response every 3-4 days, an increase of 4.8 g per day to a maximum dose of 20 g/day. After reaching the optimal piracetam dose, it is advisable to find a way to reduce the dose of the attached drugs.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when using overdose?

There is no need for special measures to overdose.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using 1 g/5 ml piracetam you may experience unwanted effects (ADR).

Common, ADR> 1/100

Body: Fatigue.

digestive: Nausea, vomiting, diarrhea, abdominal distention. nerve: restlessness, prone to agitation, headache, insomnia, sleep.

Uncommon, 1/1000

Body: Dizziness.

nerve: Run, sexual stimulation.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Piracetam 1 g/5 ml contraindicated in the following cases:

Severe renal failure (creatinine clearance coefficient below 20 ml/minute).

People with Huntington.

Patients with liver failure.

Be cautious when used

Because Piracetam is eliminated through the kidneys, the half -life of the drug increases directly to the degree of renal failure and creatinine clearance. It is necessary to be very cautious when taking the drug for people with renal failure. Need to monitor kidney function in these patients and in the elderly.

When the evaluation coefficient of creatinine is below 60 ml/minute or when serum creatinine is over 1.25 mg/100 ml, the dose must be adjusted.

Creatinine clearance coefficient is 60 - 40 ml/minute or when serum creatinine is 1.25 mg - 1.7 mg/100 ml (half -life of piracetam is more than twice as long). Only 1/2 normal dose should be taken.

Creatinine clearance coefficient is 40 - 20 ml/min, serum creatinine is 1.7 - 3.0 mg/100 ml (half -life of piracetam is 25 - 42 hours). Use 1/4 normal dose.

The ability to drive and operate machinery

Precautions when taking the drug because the drug can cause chicken sleep.

Pregnancy

Piracetam can be through the placenta. Do not use this medication for pregnant people.

Breastfeeding period

Do not take this medication.

Drug interaction

can still continue the classic method of alcoholic treatment (vitamins and sedatives) in the case of a person with vitamin deficiency or strong agitation.

There have been cases of interaction between piracetam and thyroid essence when used simultaneously: confusion, stimulation and sleep disorders.

In a patient, prothrombin time has been stabilized by warfarin when using piracetam.

Storage

In a dry place, the temperature does not exceed 30 0C, avoiding light.

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