Piropharm 20mg Imexpharm treat rheumatoid arthritis, osteoarthritis (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Piroxicam

Ingredient

Composition information	Content
Piroxicam	20mg

Uses

Indications

Piropharm 20 mg is indicated in the following cases:

rheumatoid arthritis and osteoarthritis, osteoarthritis.

Againonitis, musculoskeletal disease and sports injury.

Sutra, dysmenorrhea and postoperative pain.

Acute gout. The mechanism of Piroxicam may be due to prostaglandin synthesis, thus preventing the formation of prostaglandin, thromboxan and other products of cyclooxygenase enzymes. Piroxicam can also inhibit the activity of neutrophils.

Piroxicam inhibits prostaglandin synthesis in the kidneys should reduce blood flow to the kidneys, which can lead to acute renal failure, water retention and acute heart failure.

Dynamic pharmacokinetics

Piroxicam is well absorbed through the gastrointestinal tract. Peak concentration in plasma is achieved from 3-5 hours after taking the drug.

Piroxicam has a liver -intestinal cycle and is very different in absorption between individuals, so the sale time of the drug in plasma varies from 20 to 70 hours. The drug is strongly associated with plasma proteins, plasma concentrations and epidemics are approximately equal when it reaches a stable state (that is, after 7-12 days).

The main metabolites of the drug are hydroxylation of the pyridin ring, followed by a complex with glucuronic acid, then this complex is excreted in urine. Less than 5% of urine elimination drugs in constant form.

Before taking Piropharm 20mg Imexpharm treat rheumatoid arthritis, osteoarthritis (10 blisters x 10 tablets)

How to use

Piropharm is an oral medication.

Dosage

Adults: Take 20 mg/day.

The drug should not be used for children. However, the dose of 20 mg/day can be used for children over 6 years old and weighs 46 kg or more with rheumatoid arthritis.

Acute gout treatment for adults at a dose of 40 mg/day for 5-7 days.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Activated carbon can reduce the absorption and reabsorption of Piroxicam effectively.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Piropharm 20 mg you may experience unwanted effects (ADR).

Unwanted effects are common

Oral stomatitis, anorexia, epigastric pain, nausea, constipation, diarrhea, anemia, leukemia, itching, rash, headache, discomfort.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Piropharm 20 mg is contraindicated in the following cases:

Hypersensitivity to piroxicam.

Stomach ulcer, acute duodenum ulcer.

History of bronchospasm, asthma, nasal polyps and quincke edema or jute due to Aspirin, or another nonsteroidal anti -inflammatory drug.

cirrhosis.

Severe heart failure.

Renal failure people with glomerular filtration level below 30 ml/min.

Caution when using

elderly people.

Disorders of bleeding, cardiovascular disease, a history of stomach -duodenal ulcer, liver failure or kidney failure.

People who are taking diuretics.

The ability to drive and operate machinery

There is no information on the use of drugs that affect the ability to operate machinery and train.

Pregnancy

Do not use piroxicam for pregnant women in the last 3 months or are about to labor because it will cause the risk of lung pressure in infants, due to arterial closing before birth. Piroxicam also inhibits labor, prolongs pregnancy and toxicity for gastrointestinal tract in pregnancy.

Breastfeeding period

Piroxicam excreted through breast milk. Not determined the safety of the drug used for mothers during breastfeeding.

Interactive drug

monitor to adjust the dose when used simultaneously Piroxicam with anticoagulant drugs and high protein -linked drugs.

Do not treat simultaneously with aspirin because it will lower the plasma concentration of piroxicam and increase unwanted effects.

When treated simultaneously with lithium will increase the toxicity of lithium due to increasing lithium concentration in plasma.

Storage

under 30 ° C, avoid moisture and light.

Other drugs

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