PM NEXTG CALOOTEC Calcium supplement, treat osteoporosis (5 blisters x 12 tablets)

Women after menopause, developing children, many physical activists always require additional calcium because the demand for calcium increases. In particular, the supply of calcium is essential to ensure the balance of calcium in female athletes during menstruation.

Bone is a complex tissue and is highly mineral, including organic substances, inorganic and minerals. Lack of a few micronutrients can also reduce bone formation and regeneration. The trace minerals act as a factor for some enzymes, related to the production of the organic part of the bone.

Microcrystalline Hydroxyapatite (MCHA) is derived from bone and provides many nutrients because it is rich in calcium, phosphorus as well as other necessary minerals such as magnesium, manganese, zinc and iron. MCHA is a natural protein with calcium and phosphorus in a natural form. The ratio of calcium and phosphorus is 2/1, is a natural ratio.

PM Nextg Cal includes calcium and phosphorus in the form of natural hydroxyapatite in the form of microscopic (MCHA), along with vitamin K1 and D3 to help supply and increase calcium absorption.

Dynamic pharmacokinetics

studies show that hydroxyapatite has good biological, calcium after being absorbed in plasma in the form of ion. The calcium of hydroxyapatite is generally better absorbing than other types of calcium supplements due to hydroxyapatite contain a proportion of calcium: phosphor = 2: 1.

When taken, vitamin D is absorbed in the ileum of the small intestine with fats different from the help of bile. Sell ​​waste time during the circulation of vitamin D from 1-2 days.

Vitamin K is absorbed in the ileum and the rosary of the small intestine. The bioavailability of vitamin K from 10-80% (average 50%), depends on the amount of fat and effect of bile acid. 90% of the absorbed vitamin K is transported on the micro -micro -body to the liver for storage.

The selling time for vitamin K is 1.5 - 3 hours. After being metabolized (oxidation) is associated with glucuronic acid and is excreted mainly in urine, partly excreted in feces.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when overdose?

The lowest level has an unwanted effect in vitamin D of 50 mcg/day.

There is no report on unwanted effects from vitamin K, so there is no maximum recommendation of vitamin K.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Be cautious when using

Vitamins cannot replace daily meals.

If symptoms do not help please consult a doctor.

Do not use more than 20 mcg vitamin D a day (this is the lowest level still without an unwanted effect).

Notify the doctor if any reaction occurs when taking the drug. If you need more information, please consult your doctor.

The ability to drive and operate machinery

can be used when driving and operating machinery.

Pregnancy

used for pregnant women.

Breastfeeding period

Used for breastfeeding women.

Drug interaction

bisphosphonates (Alendronate, Etidronate, ibandronate , RiseDronate and tilronate ): Calcium supplements reduce bisphosphonate absorption. Patients should take bisphosphonate 30 minutes before taking calcium, but it is best to take the drug in 2 different sessions of the day.

Calcium increases the toxicity of glycosides digitalis on the heart because of increased blood calcium levels will increase the inhibitory effect of Na+ - K+ - Atpase of the heart glycoside. The doctor's consultation should be consulted about the appropriate dose of calcium as well as checking the level of blood calcium if necessary.

The amount of calcium should be adjusted if used with digoxin because it is likely to affect blood calcium levels. When using calcium, along with levothyroxine or some groups of quinolone or tetracycline antibiotics, should ask the doctor's idea before use.

No treatment simultaneously with cholestyramin or colestipol, phenobarbital or phenytoin, corticosteroids, as they can hinder the absorption of vitamin D or reduce the effect of vitamin D. simultaneous treatment of vitamin D with thiazid diuretic in patients with hyper thyroid discharge that can increase blood calcium.