PMS-Zanimex 250mg Imexpharm Treatment Treatment of Ear Nose and Nose Infection (2 blisters x 5 tablets)

Dosage form Box of 2 blisters x 5 tablets
Specifications Cefuroxime

Ingredient

Composition informationContent
Cefuroxime250mg

Uses

Indications

PMS-Zanimex 250mg drug is indicated in the following cases:

  • Infection with ear, nose and throat: otitis media, sinusitis, tonsillitis, pharyngitis.
  • Lower respiratory infections: pneumonia, acute bronchitis and exacerbations of chronic bronchitis.
  • Skin infections and soft tissue: Imposure, pus disease, boils.
  • Urinary - genital infections: cystitis, nephritis - pyelonephritis, urethritis.
  • Inventure of gonorrhea.
  • The first Lyme disease is manifested by the erythema symptoms caused by Borrelia Burgdorferi.
  • Bone and joint infections.
  • Meningitis due to sensitive bacteria. Cefuroxim has antibacterial activity due to synthetic inhibition of bacterial cell walls by engaging in essential target proteins. Cefuroxim has antibacterial activity on many common pathogens, including beta-lactamase strains of gram-positive and gram-negative bacteria. Cefuroxim is particularly durable with many beta-lactamase enzymes of gram-negative bacteria.

    antibacterial spectrum:

  • Gram -negative aerobic: E. Coli, Klebsiella Sp, Proteus Mirabilis, Providencia Sp, Proteus Rettgeri, Haemophilus Influenzae (including ampicillin resistance strains), Haemophilus parainfluenzae, Branhamella Catarrhalis, Neisseria Gonorrhoea (including the other (including the other (Neisseria The strain has penicillinase and no penicillinase secretion).
  • Gram -positive aerobic: Staphylococcus aureus and Staphylococcus Epidermidis (including penicillinase production strains except methicillin strains), Streptococcus group B (Streptococcus agalactiae), Streptococcus pyogenes (and Streptocci Beta), Streptococcus pneumoniae.
  • anaerobic: Gram -positive and gram -negative bacteria (including peptococcus, Peopleostreptococcus spp). Gram -positive bacillus (including Clostridium sp) and Gram -negative bacilli (including bacteroides and fusobacterium spp), propionibacterium sp. Cefuroxim is widely distributed throughout the body. The drug through the bloody barrier when the meninges are inflamed. The drug is given the placenta and is excreted through breast milk. The maximum concentration in the serum is about 2-3 hours after drinking during meals. Serum half -life is from 1 to 1.5 hours. Cefuroxim is not metabolized and eliminated in the form of non -variable according to the glomerular filtration mechanism and excreted in the renal tubules.

    • Before taking PMS-Zanimex 250mg Imexpharm Treatment Treatment of Ear Nose and Nose Infection (2 blisters x 5 tablets)

    How to use

    10 - 14 days of treatment

    Should drink at meals to increase bioavailability. Swallowing the tablet, should not be chewed by the bitter taste

    Dosage

    Adults

    Most infections

    250 - 500mg x 2 times/day.

    Urinary infection

    125mg x 2 times/day.

    Lower respiratory infections

    250 - 500mg x 2 times/day depending on the infection.

    Pyelonephritis - Pyelonephritis

    250mgx 2 times/day.

    Invalid illness

    single dose 1g.

    New Lyme disease

    500mg x 2 times/day, for 20 days.

    Children

    Most infections

    125mg x 2 times/day, up to 250mg/day.

    Children 2 years of age and older suffer from otitis media or worse infections

    250mg x 2 times/day, up to 500/day.

    PMS-Zanimex 250mg tablets are not suitable for use for patients who cannot swallow pills. There is no experience using PMS-Zanimex for children under 3 months old.

    Patients with renal failure

    Creatinine clearance (ml/minute)

    Dosage

    20

    No dose adjustment.

    Discount 50% of the dose compared to normal doses, drink 1 time/day.

    Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

    What to do when using overdose?

    Most of the nausea, vomiting, diarrhea, in addition can increase muscle stimulation and seizures, especially in people with kidney failure.

    Handling

  • Protects the respiratory tract for patients, ventilation and infusion.
  • If convulsions, stop drugs, use anti -seizures.
  • Hemorrhage can be from the circulatory system.

    • What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

    Side Effects

    When using PMS-Zanimex 250mg, you may experience unwanted effects (ADR).

    Unwanted effects because Cefuroxim is usually light and lasts only in a short time.

    Common

    diarrhea, lumpy skin rash.

    rarely

    Nausea, vomiting, eucalyptus loves eosin, leukopenia, urticaria, itching, anaphylactic reaction, candidiasis infection.

    rarely

    Hemolytic anemia, fake colitis, jaundice, acute kidney failure and interstitial nephritis.

    Instructions on how to handle ADR

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    PMS-ZANIMEX 250mg contraindications in the following cases:

  • Hypersensitivity to antibiotics of cephalosporin and the ingredients of the drug. For patients with hypersensitivity to penicillin antibiotics, it is advisable to consider cross -allergies.

    • Precautions when using

    There is a report on fake colitis when using broad spectrum antibiotics, so it is necessary to pay attention to this diagnosis in patients with severe diarrhea related to the use of antibiotics. Be careful to use this medication for people with gastrointestinal diseases, especially colitis.

    Prolonged treatment with Cefuroxim may increase non -sensitive bacteria. Need to monitor patients need kidneys. If serious superinfection during treatment, the drug must be stopped.

    Be careful when giving patients simultaneously with strong diuretic drugs because it can be effective for kidney function.

    The ability to drive and operate machinery

    There has been no recognition of the effects of the drug on the ability to operate machinery and trains. However, it is advisable to notify the patient the unwanted effects such as: discomfort, headache when taking the drug.

    Pregnancy

    There has been no complete research on drug use for pregnant women. Need to be cautious when using; Should consider the benefits of the mother and the danger to the fetus.

    Breastfeeding period

    cefuroxim excreted through breast milk, should stop breastfeeding during treatment.

    Drug interaction

    Ranitidin, sodium bicarbonate: reduces the bioavailability of cefuroxim. It is advisable to be used atfuroxim at least 2 hours after the antacids or H2 histamine inhibitors, as these drugs can increase the stomach pH.

    High doses Probenecid reduces Cefuroxim clearance in the kidneys, making Cefuroxim concentration in plasma higher and longer.

    aminoglycosides or strong diuretic drugs: increase the likelihood of kidney poisoning.

    Cefuroxim can affect the intestinal bacteria, reducing estrogen reabsorption. Therefore, the drug can reduce the effect of oral contraceptives containing estrogen and progesterone.

    Storage

    less than 30 ° C, avoid moisture and light.

    Other drugs

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