Polcalmex polfarmex syrup - Division and treatment of calcium deficiency (150ml)

Dosage form Syrup
Specifications Box X 150ml
Ingredient Calcium lactobionate, calcium Glubionate

Ingredient

Thành phần cho 150ml

Composition information	Content
Calcium lactobionat	9.6g
Calci Glubionate	44.1g

Uses

Indications

Polcalmex drugs are indicated in cases of prevention and treatment of calcium deficiency.

Pharmacokology

Calcium is a basic nutrient, affecting the maintenance of electrolytes as well as the exact activity of many regulatory mechanisms. It plays an essential role in the physiological process of formation and regeneration of bone tissue, neuromuscular transmission, regulating muscle spasms, stimulating bone, blood clotting, excretion and activating some hormones, enzymes and neurotransmitters, salt and water transport, absorbent properties of cell membranes and blood vessels.

Polcalmex affect endothelial closing, reducing edema and allergic reactions, restoring the accuracy of muscle contraction and reducing calcium deficiency.

Thanks to the increase in proportion, the pharmacological dosage of calcium will stimulate the secretion of calcitonin, is a neurotransmitter, stimulating the secretion of beta-endorphin, has an analgesic and antidepressant effect, it also stimulates physical activity, stops the hormone secretion of the armor gland and reduces phosphate levels in plasma.

pharmacokinetic

absorption

Calcium is absorbed in the duodenum and the first part of the small intestine thanks to the active transport mechanism. About 30% of calcium oral during the absorbed meal.

Increased calcium absorption when lactose, protein, citric acid, vitamin D, parathyroid gland hormone, and glucocorticoid, calcitonin, oxalic acid, phytic acid and phosphate to stop calcium absorption.

Calcium absorption has decreased with age. The appropriate calcium content in the serum is about 2.5mmol/l, of which 1.5mmol/l calcium ionization and about 1mmol/l is linked to plasma proteins.

Elimination

calcium is excreted through feces and urine, a small amount through saliva, sweat and milk. The amount of calcium excreted through the stool is relatively stable, about 0.4 - 0.8g/day. The amount of calcium excreted in urine is influenced by calciotropic hormones, under appropriate conditions not exceeding 0.3g/day.

Before taking Polcalmex polfarmex syrup - Division and treatment of calcium deficiency (150ml)

How to use

Oral drugs.

Dosage

additional treatment until the blood calcium level is maintained at a normal level.

Children under 2 years of age taking the drug as directed by the doctor.

Children 2–11 years old: 2.5 - 5ml x 2 times/day.

Children 12–17 years old: 5 - 10ml x 2–3 times/day.

Adults: 15ml x 2-3 times/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Polcalmex, you may experience unwanted effects (ADR).

High doses can cause digestive disorders (constipation). Long -term treatment can cause hypercalcemia and hypercalciuria.

Although rarely occurs cases of hypercalcemia unless the kidney function is impaired, the following symptoms may indicate the ability to have hypercalcemia: nausea, vomiting, anorexia, constipation, abdominal pain, bone pain, thirst, multi -urinary, weakness, drowsiness or confusion.

The kidneys in patients with hypercalculoma secreted higher amounts of calcium, which can lead to kidney stones and bone defects that cause osteoporosis and bone deficiency.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Polcalmex drugs contraindicated in the following cases:

Hypersensitivity to the active ingredient or ingredients of the drug.

Hyperculine hypercalcemia, hypercalcium, calcium stones, calcification of tissue.

Progressive renal failure.

Caution when using

The drug contains Sucrose excipients, so it can cause side effects in diabetes patients. Patients with rare genetic problems are intolerant to fructose, poorly absorbing glucose -Galactose or Sucrose - Isomaltase deficiency should not use this drug. Use cautiously for patients with hyperthyroidism, heart disease, sarcoid disease (benign lymphoma) and kidney stones.

1ml of polcalmex syrup contains 2mg of sodium benzoate equivalent to 0.319mg of sodium, less than 1mmol sodium (23mg) in 5ml, so it can be considered as no sodium.

The ability to drive and operate machinery

Siro Polcalmex does not affect the ability to drive and operate machinery.

Pregnancy

Used only as directed by the doctor.

Controlled studies in women do not show any risk in the fetus when taking the drug in the first 3 months of pregnancy; There is no sign that the use of drugs is likely to be dangerous in the next months of pregnancy and the ability to adversely affect the fetus is almost none.

during pregnancy should be used in accordance with the recommended dosage.

Breastfeeding period

When breastfeeding should be used according to the recommended dosage. Calcium supplemented with milk, but with the concentration that is not enough to cause any adverse effects on babies.

Drug interaction

Do not use calcium for at least 3 hours before or after taking tetracycline, doxycycline, fluor, biphosphonate, phenytoin, quinolone by being able to create difficult to dissolve complexes.

Simultaneous use with vitamin D will increase calcium absorption.

The thiazide diuretics reduce calcium urinary so there is a risk of increased blood calcium.

In patients with digitalis treatment, using high doses of calcium can increase the risk of arrhythmia.

Some foods reduce calcium absorption such as cocoa, tea, chocolate, beans, whole grains, grain vegetables, spinach.

Storage

Store under 30ºC.

Other drugs

Disclaimer

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