Polygynax Innothera Chouzy vagina treatment for vaginitis, vulva - vagina (2 blisters x 6 tablets)

Dosage form Box of 2 blisters x 6 tablets
Specifications Neomycin, polymyxin b, nystatin

Ingredient

Composition information	Content
Neomycin	35000
Polymyxin b	35000
Nystatin	100000

Uses

indications

Polygynax drugs are indicated in adults used in the following cases:

Vaginitis, vulva-navigant, nautical uterine vagina (due to bacterial impurities), with or without fungal superinfection (Candida albicans). Neomycin, polymyxin B sulfate and nystatin, so it works for both bacteria and fungi.

neomycin:

A aminoglycosid antibiotic antibiotics that kill bacteria that inhibit bacterial protein biosynthesis, produce abnormal proteins, causing bacteria not to grow and survive.

Neomycin -sensitive bacteria such as Staphylococcus aureus, Escherichia Coli, Haemophilus Influenzae, Klebsiella, Entobacter of all kinds, Neisseria of all kinds. Neomycin does not work with Pseudomonas Aeruginosa, Serratia Marcescens, Streptococci including Streptococcus Pneumoniae or Streptococcus hemolysis.

polymycin:

is a drug that has a bactericidal effect. The drug is attached to phospholipids that change the permeability and change the bacterial cell membrane structure, causing leaks of internal components. Antibacterial activity of polymycin B restricted on Gram -negative bacteria, including Enterobacter, E.coli, Klebsiella, Salmonella, Pasteurella, Bordetella, Shigella and Pseudomonas Aeruginosa.

nystatin:

is an anti -fungal antibiotic extracted from streptomyces nouseri mushroom culture. Nystatin has the effect of restraining or eliminating fungi depending on the concentration and sensitivity of the fungus, which does not work on the normal bacteria of the body. The most sensitive are yeast and very good effects on Candida Albicans.

The effect of nystatin is to link to the sterol of the cell membrane sensitive mushrooms that change the bobbing properties of the mushroom. Nystatin tolerates well even when long -term treatment and does not cause drug resistance.

pharmacokinetics

neomincin:

When the drug is absorbed, the same as after taking 3G, the peak concentration in the serum is about 4kg/ ml. The absorption of the drug may increase when the mucosa is inflamed or damaged. When absorbed, the drug will quickly be eliminated through the kidneys in the form of activity. Half life of the drug is about 2-3 hours.

polymycin:

Good peritoneal absorption, not absorbed through the gastrointestinal tract, except for children may be able to be absorbed up to 10% of the dose, not significantly absorbed through the mucosa and intact skin or peeling the outer coating as in the case of severe burns. Polymycin B is widely distributed in the body tissue, does not see the distribution in the cerebrospinal fluid and does not pass the placenta.

Polymycin B is not much attached to plasma proteins. Half of the lifetime elimination of adults with normal kidney function is 4.3 - 6 hours. About 60% of the absorption drug is eliminated in the form of unchanged urine through glomerular filtration.

nystatin:

The drug is not absorbed through the skin, mucosa when used on the spot.

Before taking Polygynax Innothera Chouzy vagina treatment for vaginitis, vulva - vagina (2 blisters x 6 tablets)

How to use

vaginal placement.

Dosage

put 1 pill in the vagina, in the evening, for 12 consecutive days.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? The long -term use is also placed in the risk of increased risk of eczema.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not use double the prescribed dose.

Side Effects

When using Polygynax, you may experience unwanted effects (ADR).

Side effects that appear depending on the individual, the side effects that occur in this person does not mean that it will be encountered in others. The following side effects may be encountered:

rash, pimples on the spot.

burns and stimulates the vagina.

Exposure dermatitis (may be seen when taking the drug for too long, repeated many times).

Expression of systemic toxicity is very limited due to short -term use. Notify the doctor any unwanted effects, including the above side effects.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Polygynax drugs are contraindicated in the following cases:

Hypersensitivity to one of the ingredients of the drug (or cross -sensitive).

allergies to soy and/or its preparations.

Use vaginal diaphragm, condoms.

Use spermicide.

Be cautious when using

stop treatment when there is a phenomenon of intolerance or allergic reaction on the spot.

Do not use this drug for patients allergic to soy and/or soy products.

Compliance with treatment time, to avoid secondary infection resistance.

Due to the lack of data on the ability to absorb Neomycin and Polymicin B of the vaginal mucosa, the risk of systemic effects, especially in the case of impaired liver, kidney function and diabetes are not excluded 1g of vaginal or condom diaphragm, due to the risk of broken, torn by drugs.

Do not use spermicide simultaneously, as this therapy can prevent the activity of local spermicide. Notify the doctor the drugs you are taking, including non -prescription drugs, before treatment with polygynax.

Treatment should be coordinated with local hygienic measures (using cotton fabric underwear, avoiding too much vaginal washing, avoiding vaginal tampons during treatment ...) and eliminating the factor of waste as much as possible.

Treatment for partners should be concerned with each case of not being used in the menstrual cycle.

The ability to drive and operate machinery

No report.

Pregnancy

There is no clinical report on side effects and toxicity when using polygynax in pregnant women. Only use this medication when prescribed by a doctor. Need to consider the benefits and risks when taking drugs for pregnant women.

The period of breastfeeding

There is no data on polygynax whether or not to excrete in milk or not, so it should not be used in the period of breastfeeding. It is necessary to consider the benefits and risks when taking medicine for women to breastfeed.

Interactive drug

Take or use other drugs.

Do not be used with spermicide (risk of active) as well as condoms or latex diaphragm (risk of tearing condoms or diaphragm).

Storage

Store drugs below 30 ° C.

Other drugs

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