Polymax 5ml Medipharco eye drops used for anti -inflammatory, anti -allergy

dexamethasone is fluomethylprednisolone, a synthetic glucocorticoid, almost insoluble in water. The glucocorticoids act by entering the cell receptor, transferring into the cell nucleus and there affects some code -translated genes. The glucocorticoids also have some direct effects, which may not be intermediaries connected to the receptor. Dexamethasone has the main effects of glucocorticoids are anti -inflammatory, anti -allergic and immunosuppressive inhibition, while the effect of electrolyting is very small. Regarding anti -inflammatory activity, dexamethasone stronger than hydrocortisone 30 times, stronger than prednisolon 7 times.

Dexamethasone is used orally, intramuscularly, injected, inhaled, or applied on the spot, to treat diseases that corticosteroids are specified (except for adrenal insufficiency) such as bleeding, trauma, surgery, or infection, brain tumor, arthritis and soft tissue such as rheumatoid arthritis, short -term treatment of self -acute, acute, acute, acute, acute, acute, acute, acute, acute, hypertensis Chronic applications such as bronchial asthma or serum disease.

Dexamethasone must be combined with body antibiotic treatment and supportive measures when needed. Dexamethasone is also used on the spot to apply to the conjunctiva, external ear or nasal mucosa to treat inflammatory symptoms or allergies in the external or eye ear canal. Corticosteroid therapy does not cure the disease, so it is necessary to identify or eliminate the cause of inflammation if possible. With pharmacological dosage, dexamethasone used body inhibits the pituitary gland release corticotropin (ACTH), causing the adrenal shell to stop the endogenous corticosteroid hormone (causing secondary adrenal shells).

If it is necessary to treat with long -term glucocorticoids, use only the drug at the lowest possible doses and usually only use as a drug that supports other treatment. When the body therapy is stopped with pharmacological doses, it will gradually reduce the dose until the function of the hypothalamus - the yen - the kidney is recovered.

naphazolin : anti -congestion effect.

riboflavin : There is no clear effect when taking or injecting. Riboflavin is transformed into 2 co-enzymes, Flavin Mononucleotide (FMN) and Flavin Adenine Dinucleotide (FAD), which are the forms of co-enzyme operating needed for tissue respiration. Riboflavin is also needed for the activation of Pyridoxine, the conversion of trytophan into niacin, and related to the integrity of red blood cells. Riboflavin is in the form of Flavin Nucleotide needed for electronic transportation systems and without riboflavin, will be lumpy of skin tanning, momentary, dry lips, tongelitis and stomatitis. There may be eye symptoms such as itching and burning, fear of light and vascular distribution disorders in the cornea.

Some of these symptoms may be a manifestation of the lack of other vitamins such as pyridoxine or nicotinic acid because these vitamins do not perform their functions without riboflavin. Lack of riboflavin can occur with vitamin B deficiency, such as Pellagra.

Lack of riboflavin can be detected by measuring the activity of glutathion enzyme reductase when adding fad on in vitro. Lack of riboflavin can occur when the diet is insufficient, or less absorbent, most common in alcoholic, liver disease, cancer, stress, bacterial infection, long -term illness, fever, diarrhea, burns, serious injuries, stomach removal, children with bilirubin and users some drugs that cause riboflavin shortage.

Dynamic pharmacokinetics

Neomycin sulfate is poorly absorbed through the gastrointestinal tract, used on the spot to treat infections. When absorbed, the drug will be eliminated quickly through the kidneys in the form of activity. Half life of the drug is about 2-3 hours.

Dexamethasone sodium phosphate is absorbed well through the gastrointestinal tract and at the position of medication, then distributed into all tissues in the body. The drug can pass the placenta and a small amount through breast milk. The drug is highly absorbed by the liver, kidneys and adrenal glands. Metabolism in the liver slowly and excreted mainly through urine mostly in the form of non -conjugated steroids. The sale time of the drug is 36 - 54 hours, so the drug is especially suitable for diseases that require glucocorticoids continuously.

naphazolin nitrate: at the spot of medication, local shrinkage occurs within 10 minutes and lasts 2-6 hours. Naphazolin can be absorbed to create system impact. There is no information about distribution and elimination of drugs on humans.

riboflavin sodium phosphate is a water -soluble vitamin, absorbed mainly in the duodenum, distributed throughout the tissue in the body, into breast milk and through the placenta. The drug is excreted by the kidneys and partly through the feces.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Be cautious when using

do not take the drug for a long time and repeat many times. If used for a long time, there must be a doctor's opinion.

Do not use the drug after opening the lid for more than 2 weeks.

The ability to drive and operate machinery

In the treatment dose, the drug does not affect the ability to drive and operate machinery.

Pregnancy

No information.

Breastfeeding period

There is no information.

Interactive drug

Do not use at the same time with anticoagulants and other eye drops.

can cause cross -allergies to gentamicin .