Potriolac ointment is centralized to treat psoriasis psoriasis, mild to medium (15g)

Dosage form Box x 15g
Specifications Calcipotriol, betamethasone

Ingredient

Thành phần cho 15g

Composition information	Content
Calcipotriol	0.75mg
Betamethasone	7.5mg

Uses

Indications

Potriolac drugs are indicated in cases of psoriasis treatment, mild to medium level.

Pharmacokology

Calcipotriol is a synthetic derivative of vitamin D3, which treats psoriasis. The exact mechanism of acting for Calcipotriol psoriasis has not been fully understood, however, the in vitro evidence shows that the drug stimulates the differentiation and proliferation of many types of cells including horn cells.

betamethason dipropionate is a synthetic corticosteroid, which has a very powerful glucocorticoid effect, with negligible mineralocorticoid effect. Betamethason dipropionate has anti -inflammatory and anti -allergic effects.

pharmacokinetic

absorption

Calcipotriol is very little absorbed through the skin. Only about 5 - 6% of calcifications are absorbed into the body for 12 hours. Betamethasone absorbs well through the skin. When applied, especially if the bandage is torn or when the skin is torn, there may be a amount of betamethasone that is absorbed enough for the whole body effect.

Metabolism

Calcipotriol is transformed into an inactive metabolic within 24 hours in the liver.

Elimination

Calcipotriol is eliminated through the bile.

Before taking Potriolac ointment is centralized to treat psoriasis psoriasis, mild to medium (15g)

How to use

Potriolac drugs are used on the skin. Apply the drug into a thin layer to the sick skin, rub gently to absorb the medicine.

Dosage

Adults

Apply medicine 1-2 times/day.

Do not use more than 100 g of ointment/week and no more than 4 weeks/treatment.

Children

Apply ointment 1-2 times/day. The maximum dose of 1 week for children from 6 to 12 years old is 50 g, for children over 12 years old is 75 g.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? When applying the drug in large amounts, it can cause hypercalcemia. If the patient has hypercalcemia due to topical, it is necessary to stop treatment until this index returns to normal.

A doses of corticosteroids overdose will probably not cause acute symptoms. The effect due to increased corticosteroids does not appear early unless use high doses in a row. In case of an overdose, the electrolyte should be monitored. Pay special attention to sodium and potassium balance. In the case of chronic poisoning, stop the drug slowly. Treatment of electrolyte imbalance if needed.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Potriolac, you may experience unwanted effects (ADR).

Unwanted effects related to the dose and duration of the drug.

Common, 1/100

Skin: skin irritation with symptoms of burning, itching, hemorrhage, dry skin, rash, rashes, dermatitis, psoriasis seriously, skin burns.

Skin: Skin atrophy, cystic inflammation, hypercalcemia, hyperpigmentation.

Notify the doctor with unexpected effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Potriolac drugs are contraindicated in the following cases:

Hypersensitivity to Calcipotriol, Betamethason or with other corticosteroids or any ingredients of the drug.

Caution when using

Avoid not to contact the face, eyes, mucosa and non -disease -free skin areas. Rinse with water if accidentally exposed to these areas.

Avoid applying it to a large or bandage. With skin folds, it is necessary to apply little medicine because it is easy to cause irritation. Patients need to wash their hands after applying the drug to avoid accidentally making the medicine on the face, eyes or skin without applying the drug.

If taking the drug for a long time can cause an increased risk of blood calcium and adrenal inhibition - pituitary gland causes secondary adrenal insufficiency. Therefore, it is necessary to monitor blood calcium and kidney function regularly.

The drug can cause transient irritation at the lesions or the surrounding skin after applying. Take care not to scratch the irritated skin. If the irritation lasts or the patient has a rash on the face or the disease is worse, it is necessary to stop the drug.

The ability to drive and operate machinery

has not been recorded.

Pregnancy

Consider the benefits and risks of the drug on the mother and the fetus.

The period of breastfeeding

Considering the benefits and risks of the drug on mothers and children.

Medicinal interaction

When taking the drug simultaneously with the treatment with ultraviolet light B, it is necessary to apply the drug at least 2 hours before or after ultraviolet rays to avoid reducing the effects of ultraviolet rays as well as calcification.

Storage

In the dry place, temperature of 30 ° C, avoiding light.

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