Prednisolone Stella 5mg anti -inflammatory, treat rheumatoid arthritis, erythema lupus (200 tablets)

Dosage form Box of 200 tablets
Specifications Prednisolone

Ingredient

Composition information	Content
Prednisolone	5mg

Uses

Indications

Prednisolone 5 mg is indicated in cases where anti -inflammatory and immunosuppressive effects need:

Treatment of rheumatoid arthritis, lupus erythematosus body, some forms of vasculitis, temporal arteritis and inflammation around the artery, sarcoid, bronchial asthma, ulcerative colitis, hemolytic anemia, granulocytopenia and severe allergens including anaphylaxis. Paralysis .

pharmacokinetics

absorption: Oral bioavailability of Prednisolone is approximately 82%. The peak concentration reaches 1–2 hours after taking the drug.

Distribution: Prednisolone is linked to plasma proteins about 90–95%. The clearance of Prednisolone is 8.7 ± 1.6 ml/min/kg. The distribution of the drug is 1.5 ± 0.2 l/kg.

Metabolism - Except: Prednisolone is metabolized in the liver into ester and glucuronide metabolites, and is excreted into urine. Prednisolone waste sale time is approximately 1.7–2.7 hours.

Before taking Prednisolone Stella 5mg anti -inflammatory, treat rheumatoid arthritis, erythema lupus (200 tablets)

How to use

Prednisolone 5 mg oral.

Dosage

The starting dose for adults can be from 5–60 mg/day, depending on the disease needed to be treated and usually divided into 2–4 times a day.

Dosage for children can be from 0.14–2 mg/kg/day or 4–60 mg/m2/day, divided into 4 times.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

In these cases, it is necessary to consider suspension or stop using glucocorticoid.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Prednisolone 5 mg, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Central nerve: Insomnia, nervousness is easily agitated.

Digestive: Increased appetite, indigestion . Skin: Skin.

Endocrine and metabolism: diabetes.

nervousness and bone: joint pain.

Eye: cataracts, glaucoma.

Respiratory: nosebleeds

Uncommon, 1/1000

Central nerve: dizziness, muscle attack, mental disorder, fake brain, headache, mood change, delirium, hallucinations, refreshment.

Cardiovascular: edema, hypertension . Skin: Acne, skin atrophy, bruising, hyperpigmentation.

Endocrine and metabolism: Cushing syndrome , inhibit the pituitary axis - kidney, slow growth, glucose intolerance, hypokalemia, alkaline infection, amenorrhea, sodium and water, hyperlem of blood glucose.

digestion: Stomach ulcer, nausea, vomiting, bloating, esophageal ulcer, pancreatitis.

nervousness and bone: muscle weakness, osteoporosis, fracture.

Other: Hypersensitivity reaction.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Prednisolone 5 mg contraindicated in the following cases:

Severe infections, except for bacterial shock and meningitis.

Too hypersensitivity to prednisolone.

Skin infections, fungi or tuberculosis.

using a living virus vaccine.

Caution when using

Use cautiously in people with osteoporosis, newly connected people (intestines, blood vessels), mental disorders, stomach ulcers, duodenum ulcers, diabetes, hypertension, heart failure and growing children.

Due to the risk of unwanted effects, caution must be used with all body corticosteroids for the elderly, with the lowest doses and in the shortest possible time.

Acute adrenal insufficiency may occur when stopping the drug suddenly after a long time of treatment or when stress.

When high doses, can affect the effects of vaccine vaccine.

Prednisolone Stella 5 mg contains lactose excipients. This medication should not be used for patients with rare genetic problems galactose intolerance, total lactase enzyme deficiency or glucose -galactose.

The ability to drive and operate machinery

no.

Pregnancy

using long -term body corticosteroids for mothers can lead to mild weight loss in newborns. Using high doses of corticosteroids in the body of the mother may cause a small risk of adrenal hygiene in newborns. In general, using corticosteroids in pregnant women requires consideration of benefits that can be achieved compared to the risks that may occur with mother and child.

Need to use corticosteroids for pregnant women with asthma because asthma is dangerous, causing lack of oxygen for the fetus. Using glucocorticoid before premature birth also promotes maturity of the child's lungs, preventing respiratory decline syndrome.

Lactation period

Prednisolone secretes breast milk with less than 1% of the dose and may not be clinically significant. Be careful when using Prednisolone for breastfeeding.

Drug interaction

Prednisolone is a cytochrome p450 enzyme induction and is the substrate of the P450 CYP3A enzyme, so this drug affects the metabolism of cyclosporin, erythromycin, phenobarbital, phenytoin, carbamazepine, ketocazole, rifample.

phenytoin, phenobarbital , rifampicin and diuretics decreased potassium can reduce the effect of prednisolone.

Prednisolone can cause hyperlem of blood glucose, so higher insulin dose is needed.

Avoid simultaneous use of prednisolone with nonsteroidal anti -inflammatory drugs (NSAID) because it can cause stomach ulcers.

Cavalry of the drug: Due to no studies on the correspondence of the drug, not mixing this drug with other drugs.

Storage

Store in closed packaging, dry place, avoid light. The temperature does not exceed 30 ° C.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.