Pymme DiaPro Mr Pymepharco treatment of diabetes 2 (2 blisters x 30 tablets)

Dosage form Box of 2 blisters x 30 tablets
Specifications Gliclazide

Ingredient

Composition information	Content
Gliclazide	30mg

Uses

Indications

pymme diaPRO MR 30mg indicated the treatment of type II diabetes regardless of insulin, coordinated with appropriate diet, when blood sugar control is not achieved by a simple diet.

Pharmacokological

Gliclazid is a anti -diabetes drug sulfonylure. The main effect of the drug is to stimulate the Beta cells to release insulin. Therefore, the drug only works in patients when the pancreas can also produce insulin. Sulfonylure may increase the amount of insulin due to reducing this hormone clearance in the liver.

Dynamic pharmacokinetics

After drinking, the plasma drug concentration increases slowly until 6 hours, the plateau concentration is from the 6th hour to the 12th hour. Gliclazid is completely absorbed.

Food does not affect the speed as well as the absorption concentration. The ratio of cohesion to plasma protein is about 95%.

Gliclazid is metabolized mainly in the liver and excreted mainly through the kidneys, less than 1% found in a constant form in the urine. T1/2 of Gliclazid from 10 - 20 hours.

The distribution volume is about 30 liters.

Before taking Pymme DiaPro Mr Pymepharco treatment of diabetes 2 (2 blisters x 30 tablets)

How to use

pymme diaPRO MR 30mg The type of long -lasting release tablet.

Dosage

Adults:

Daily dose can range from 1-4 capsules a day, drink only once at breakfast. The recommended starting dose is 1 tablet (30 mg/day).

If blood sugar is satisfactorily controlled, the dose can be increased to 2 tablets (60 mg), 3 tablets (90 mg) or 4 tablets (120 mg), by increasing the dose of hiccups, each increase the dose is at least 1 month apart, except in patients with blood sugar without decreasing after 2 weeks of treatment.

Maximum dose recommended is 120 mg/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when using overdose?

Case mild, treat mild hypoglycemia by drinking a cup of sugar water or fruit juice for 2 or 3 teaspoons of sugar.

In case of severe, vigorous manifestation, 10% or 30% intravenous glucose must be used and transferred patients to the hospital.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

Unwanted effects include excessive hypoglycemia, digestive disorders, nausea, headache, rash.

rarely see leukopenia, anemia, skin reaction, mucosa.

Very rarely have a state of drowsiness, sweating, increasing heart frequency, pale skin, hungry.

Notice the unwanted physician when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Pymme DiaPRO MR 30mg contraindications in the following cases:

Patients who are sensitive to Gliclazid or with other sulfonylure, sulfonamid. pregnancy and lactation.

Be cautious when using

Choose a reasonable dose for each patient to avoid the risk of hypoglycemia.

Be cautious when taking drugs in older patients, malnutrition or exhaustion, patients with adrenal impairment, pituitary insertion.

Use drugs for pregnant or lactating women

Pregnancy: contraindicated use of gliclazid.

Breastfeeding period: It is unclear whether the drug is distributed into the milk or not. However, hypoglycemia in young children is likely to occur, so do not use gliclazid for breastfeeding people.

The effect of the drug on the ability to drive and operate machinery

must be alert the symptoms of hypoglycemia and caution when driving or operating machinery,

Drug interaction

Increased risk of hypoglycemia:

nonsteroidal anti -inflammatory drugs (especially aspirin).

Sulfamid antibacterial drugs.

anticoagulant, COMAIN, IMAO, BETA, DIVIPAM, TETRACYCLIN, TETRACYCLIN, CHLATAMPHENICOL, Clofibrat, Miconazol, Alcohol.

*Reduce hypoglycemia:

barbituric, corticosteroid, salt diuretic and oral contraceptives.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

Other drugs

Disclaimer

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