Quastef 125 mekophar oral powder treatment for upper respiratory infections (10 packs x 3.8g)

Dosage form Box of 10 packs x 3.8g
Specifications Cefuroxim

Ingredient

Composition information	Content
Cefuroxim	125mg

Uses

indications

Quincef 125 is indicated in the following cases:

The drug is indicated for treating infections caused by sensitive bacteria:

Upper respiratory tract: otitis media , sinusitis, tonsillitis and sore throat.

Lower respiratory tract: pneumonia, acute bronchitis and exacerbations of chronic bronchitis .

Urinary - genital: renal inflammation - pyelonephritis, cystitis and urethritis, ....

Skin and soft tissue: boils, pus disease, impetigo.

Gonorrhea : Excessive urethritis caused by gonorrhea and cervicitis.

cefuroxime acetyl is also taken to treat Lyme disease in the beginning.

Pharmacy

cefuroxime is a semi -synthetic antibiotic with wide antibacterial spectrum, belonging to cephalosporin group. Cefuroxime has antibacterial activity due to synthesis of bacterial cell walls by attaching essential target proteins.

Cefuroxime has a good and anaerobic gram -negative and anaerobic activity, including most staphylococcus strains of penicillinase secretion, and has gram -negative antibacterial activity. Cefuroxime often works for the following bacteria: Aerobic Gram: Haemophilus Influenzae (including Ampicillin resistance), Moraxella CatVrhalis, Neisseria Gonorrheae, Escherichia Coli, Klebsiella, Proteus; Aerobic Gram: Staphylococcus aureus, Staph. Epidermidis, Streptococcus Pneumoniae, Streptococcus Group B; Anaerobic: Gram -positive and gram -negative bacteria (including peptococcus and peptostreptococcus species), Gram -positive bacilli (including Clostridium Species), gram -negative bacillus (including Bacteroides and Fusobacterium species)

Dynamic pharmacokinetics

cefuroxime acetyl will be absorbed through the digestive tract and quickly hydrolyze in the intestinal mucosa and in the blood to release Cefuroxime into the circulatory system.

cefuroxime is widely distributed throughout the body, including pleural fluid, phlegm, bone, fluid and aquatic fluid.

Cefuroxime is not metabolized and eliminated in the form of unchanged, about 50% through glomerular filtration and about 50% through excretion in the renal tubules. Cefuroxime only excreted in bile with very small amounts.

Before taking Quastef 125 mekophar oral powder treatment for upper respiratory infections (10 packs x 3.8g)

How to use

oral medication.

Dosage

as directed by the doctor.

Recommended dose

Adults

Most infections: 250mg x 2 times/day.

Urinary infection: 125mg x 2 times/day.

Bronchitis and pneumonia: 500mg x 2 times/day.

Children

Most infections: 125mg x 2 times/day.

Children 2 years of age and older sufferer from otitis media or worse infections: 250mg x 2 times/day.

Treatment time is from 5 to 10 days. Should take medicine after eating to achieve optimal absorption.

There is no need to adjust the dose in case of renal failure, the patient is making kidney feces or in the elderly, if used not exceeding the maximum of 1g/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Symptoms

Most drugs only cause nausea, vomiting and diarrhea. However, it may cause an increase in nervous stimulation and seizures, especially in people with kidney failure.

How to handle

Protects the respiratory tract of the patient, supports ventilation and infusion. If developing convulsions, stop using the drug immediately; Anti -seizures may be used if clinically indicated. Hemorrhage can eliminate blood from the blood, but most of the treatment is supporting and resolving symptoms

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using quincef 125 , you may experience unwanted effects (ADR).

Common

diarrhea, lumpy skin.

Anaphylaxis reactions, candidiasis infections, eosinophilia, Eosin, leukopenia, neutropenia, positive Coombs test, nausea, vomiting, urticaria, itching, creatinine in serum.

Fever, hemolytic anemia, fake colitis, polymorphic erythema, Stevens - Johnson syndrome, poisoned epidermal necrosis, cholestatic jaundice, AST and ALT, kidney toxicity has temporary hyperurine, creatinine, interstitial nephritis, convulsions, headaches, agitation, joint pain.

Instructions on how to handle ADR

Notify the doctor the unwanted side effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Quincef 125 contraindications in the following cases:

Patients with a history of allergies to antibiotics of cephalosporin.

Be cautious when using

need to be careful especially when indicated for patients with a history of anaphylaxis with penicillin.

Be cautious when giving patients simultaneously with strong diuretic drugs, because it can have adverse effects on kidney function.

using long -term cefuroxime can cause non -sensitive strains to grow too much, need to monitor the patient needs kidney, if superinfected during treatment, must stop using the drug.

There has been a fake colitis report that occurs when using broad spectrum antibiotics, so it is very cautious.

The ability to drive and operate machinery

Caution when used for train drivers or operating engine.

Pregnancy

Precautions when using drugs for pregnant women in the first months of pregnancy.

breastfeeding period

Be cautious when using the drug for nursing women.

Drug interaction

ranitidine with sodium bicarbonate reduces the bioavailability of cefuroxime acetyl. Cefuroxime acetyl should be used at least 2 hours after taking antacids or H2 blockers, as these drugs can increase the stomach pH.

High -dose probenecid use reduces the level of Cefuroxime clearance in the kidney, making the cefuroxime concentration higher and longer. Used with aminoglycoside increases the likelihood of kidney poisoning.

Storage

The dry place (70%humidity). Temperature 30 ° C. Avoid light.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.