Ratidin F Pharmedic treatments for stomach ulcer, duodenum (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Ranitidine

Ingredient

Composition information	Content
Ranitidine	300mg

Uses

Indications

Ratidin F medicine is indicated in the following cases:

Treatment of duodenal ulcer, benign stomach ulcer, after surgery.

Rodbating esophagitis.

Treatment of Zollinger - Ellison syndrome.

The necessary cases to reduce gastric secretion and reduce acid secretion.

Pharmacokology

Ranitidin is a H2 histamine receptor antagonist, inhibits competition with histamine in the H2 receptor of the wall cells, reduces the amount of gastric acid secreted day and night, even in food stimulated by food, insulin, amino acid, histamine or pentagastrin.

pharmacokinetic

bioavailability of ranitidin is about 50%. After taking Ranitidin quickly absorbed from the digestive tract, the peak concentration of plasma reaches 2-3 hours after drinking. The absorption is not significantly reduced by food and antacids. Ranitidin is excreted mainly in urine, the rest is discharged through feces. Selling time is about 2-3 hours. About 35% of oral doses except for the kidneys in the form of constant 24 hours.

Before taking Ratidin F Pharmedic treatments for stomach ulcer, duodenum (3 blisters x 10 tablets)

How to use

Take oral use.

Dosage

Treatment of duodenal ulcer, benign stomach ulcers

Take ½ tablet in the morning and ½ tablet in the evening or take 1 tablet in the evening, treat for 4-8 weeks, with patients with chronic gastritis for 6 weeks, with patients with ulcers due to non -steroid anti -inflammatory drugs for 8 weeks, with people with duodenal ulcer, can take 1 tablet, 2 times/day, for 4 weeks to heal ulcers.

Rodbing lemoon inflammation

Take ½ tablets in the morning and ½ tablet in the evening or take 1 tablet in the evening, treat 8 - 12 weeks. When you have recovered, for long -term maintenance, tablet tablets, 2 times a day.

Treatment of Zollinger - Ellison syndrome

Take ½ tablets, 3 times/day. Can drink up to 6g/day, divided into several times.

To reduce stomach acid (prevent acid inhalation) in obstetrics

Take ½ tablet at labor, then every 6 hours to drink 1 time.

Dosage for children

Should use the type of tablet with the content of ranitidin 150mg accordingly.

Dosage for treatment of peptic ulcer in children

Take 2 - 4mg/kg, drink 2 times/day, maximum of 300mg/day.

Maintenance dose of 2 - 4mg/kg, oral 1 time/day can be used, up to 150mg daily.

Although there is very little information about the use of ranitidine for reflux esophagitis and esophageal ulcer in children, dose of 5 - 10mg/kg a day, often divided into 2 times, used.

Dosage for people with kidney failure

Trusting information about drug recommended ranitidine dose is reduced in patients with severe renal impairment. For patients with creatinine clearance below 50ml/min, oral doses of 150mg/day are recommended, can be cautious to increase to 150mg every 12 hours if necessary.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

There is no specific antidote, so it is necessary to support support and symptoms.

What to do when forgetting a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Ratidin F 300, you may experience unwanted effects (ADR).

Common

Headache, dizziness, fatigue, diarrhea, erythema.

rarely

leukopenia, thrombocytopenia, itching and enameled transaminase.

Very rare

Hypersensitivity reactions (urticaria, bronchospasm, anaphylaxis, angioedema, muscle pain, joint pain), granulocytosis, reducing all bloody hemorrhage, slow heart rate, hypotension, atrial hell, breast enlargement in men, inflammation, hepatitis, eye disorders.

Instructions on how to handle ADR

Notify the doctor the unwanted effects encountered when using Ratidin f.

Warnings

Before using Ratidin F, you need to read the instructions for use and refer to the information below.

Contraindicated

Ratidin F 300 drug is contraindicated in the following cases: Allergy to any component of the drug.

Precautions when using

should adjust the dose in patients with renal function.

Patients with severe hepatic impairment, acute porphyrin metabolism disorders, heart disease.

It is necessary to rule out the possibility of stomach malignant tumor before treatment with ranitidine.

The ability to drive and operate machinery

Ratidin F medicine can cause headaches, dizziness, fatigue, so do not drive or operate machinery when taking the drug.

Pregnancy

The dose of treatment does not see any harm to the pregnant mother, the birth and health of the fetus.

Breastfeeding period

Drug interaction

ranitidin inhibits very little metabolism in the liver of some drugs (anticoagulants - Coumarin, Theophylin, Diazepam, Propranolol).

Use with the same glipizid has the effect of lowering blood pressure but does not seem to occur.

ranitidine reduces the absorption of ketoconazole, fluconazole and otraconazole due to ranitidine reduces the acidity of the stomach.

Use with clarithromycin increases ranitidine concentration in plasma.

Use with propanthelin bromid increases the peak concentration of ranitidine in plasma and slow absorption.

Storage

At a temperature not exceeding 30 °. Avoid light.

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