Reamberin polysan infusion solution reduces oxygen and detoxification (400ml)

Dosage form Bottle x 400ml
Specifications Sodium chloride, potassium chloride, magnesium chloride, sodium hydroxide, stored injected, sodium sucinat

Ingredient

Composition information	Content
Sodium chloride	2400mg
Potassium chloride	120mg
Magnesium Chloride	48mg
Sodium hydroxide	710mg
The water is stored in the injection phase	400ml
Sodium Succinat	6g

Uses

Indications

Reamberin 400 ml drugs are prescribed for adults and children over 1 year of age as anti -oxygen and detoxification drugs in cases of poisoning due to many different causes.

Pharmacokology

Reamberin drugs have anti -oxygen and antioxidant properties, which are significantly effective on the process of energy in cells, reducing free radicals and restoring cell activity. The drug activates the enzymes of the Krebs cycle and improves the effectiveness of the use of fatty acids and glucose of the cell, normalize alkali -acid -acid and gas composition. The drug also has a mild diuretic effect.

After intravenous infusion, Reamberin is quickly used so there is no accumulation in the body.

Mechanism of action:

Succinat salt transmission in Reamberin ingredient belongs to the endogenous precursor group of cells, comes with two main effects: enhancing carbohydrate exchange and phosphorinization process.

Succinic acid increases the rotation of the tricarboxylic acid ring by reducing lactate, pyruvate and citrate concentration accumulated in cells at the oxygen reduction period. Thus Succinic acid ensures energy formation due to the enhancement of ATP necessary for protein synthesis.

Succinic acid increases the ability to use oxygen of cells and improves cell respiration due to enhancing the electronic current in the respiratory chain of mitochondria and increases the difference of transport membrane proton.

In the context of oxygen deficiency, the enzyme activity in the Krebs cycle is rapidly reduced (critical state, multiple viscera, acute poisoning) Succinic acid used will absorb through the metabolism of the Succinatdehydrogenase system, in which the optimal use of Succinic Acid as oxidants in the respiratory chain of the mitochondria.

Thus, Reamberin medicine, 1.5 % transmission solution shows clearly metabolic and detoxifying effects, so this is a promising drug in emergency resuscitation and active treatment.

pharmacokinetic pharmacokinetics

Studies of 1.5 % Reamberin transmission solution shows that, when intravenous infusion at a dose of 5 mg/kg body weight, the peak concentration of the drug in the blood observed for 1 minute after transmission and then rapidly reducing the concentration to 9 - 10 mg/ml, reaching the initial level of sucinic acid (1 - 6 mg/ml) after 40 minutes when transmitted. Due to the rapid use of Reamberin's components, the drug concentration in serum when the biochemistry is almost equal to the departure level. Eliminating drugs mainly in the liver and excreted in urine.

Before taking Reamberin polysan infusion solution reduces oxygen and detoxification (400ml)

How to use

Reamberin 400 ml drugs are used intravenously.

Dosage

Adults: Reamberin is intravenously, drip at no more than 90 drops/minute (no more than 1 - 4.5 ml/min). For adults, the daily dose is from 400 - 800 ml. The transmission speed and dosage are determined in accordance with the patient's condition.

Children over 1 year of age: intravenous dripping, at a speed of about 3-4 ml/min. Dosage 6 - 10 ml/kg weight/day but not more than 400 ml.

The treatment can last up to 10 days, depending on the degree of disease.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Need to apply symptomatic therapies if overdose occurs.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when forgetting a dose?

Side Effects

When using Reamberin 400 ml, you may experience unwanted effects (ADR).

Do not observe the side effects of the drug if the Reamberin transmits at the prescribed speed. If transmission is too fast, there may be the following side effects:

Rare, 1/10000

Systemic disorders and on -site effects: irritating at the location of the transmission, edema, venous inflammation.

The immune system: allergies.

Vascular disorders: Low blood pressure, high blood pressure, instant reactions such as hot burning, erythema.

Instructions on how to handle ADR

If the side effects appear to slow down the transmission speed. Notify the doctor's side effect when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Reamberin 400 ml drugs in the following cases:

Hypersensitivity to the ingredients of the drug.

Precautions when used

The phenomenon of blood and urine alkaline may occur because the blood sugar levels decrease due to the drug activation of the body.

Reamberin drugs need to be careful when used with alkaloids.

The ability to drive and operate machinery

so far there has been no specific research of the effect of the drug on the ability to drive and operate machinery. However, using the drug can affect the ability to drive and operate machinery. Therefore, Reamberin should not be used for these objects.

Pregnancy

Do not take drugs during pregnancy.

Breastfeeding period

Do not take medicine during breastfeeding.

Drug interaction

Reamberin is compatible with antibiotics, water -soluble vitamins and glucose solutions.

Storage

Store at a place to avoid light at a temperature below 30 ° C.

The drug can be cooled. Do not use if the drug is discolored or precipitated.

Expiry date: 5 years from the date of manufacture. Do not use expired drugs.

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