Rifampicin 150mg Mekophar Treatment of Tuberculosis, Wind (250 tablets)

Dosage form Box of 250 tablets
Specifications Rifampicin

Ingredient

Composition information	Content
Rifampicin	150mg

Uses

Indications

Rifampicin medicine is indicated in the following cases:

Treatment of tuberculosis, leprosy and severe bacterial infections caused by gram -positive and gram -negative bacteria.

rifampicin is a semi -synthetic antibiotic belonging to the Rifamycin family, with bactericidal activity against mycobacterium strains and gram -positive bacteria.

Rifampicin also against Gram -negative bacteria at higher concentrations.

The mechanism of action is to prevent bacterial biosynthesis bacteria by inhibiting RNA - polymerase.

pharmacokinetics

No information.

Before taking Rifampicin 150mg Mekophar Treatment of Tuberculosis, Wind (250 tablets)

How to use

Rifampicin medicine is used orally. Should drink when hungry with 1 cup of water full (1 hour before eating or 2 hours after eating)

Dosage

Tuberculosis

1 time, adults and children: 10 mg/kg body weight, maximum 600 mg, used in combination with other antiviral drugs (Inh, Streptomycin, Ethambutol ...)

leprosy

1 time, children 0 - 5 years old: 150 - 300 mg; Children 6 - 14 years old: 300 - 450 mg; Adults: 600 mg used in combination with other anti -leprosy drugs (Dapson, Clofazimin).

Meningitis prevention

Do Heamophilus Influenzae: once a day, use 4 consecutive days, children

Do Neisseria meningitidis: 2 times a day, take 2 consecutive days, children

Severe disease of Gram -positive bacteria and grams

Children

Brucella disease

Rifampicin 900 mg/day/1 time in combination with Doxycycline.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms

Nausea, sleep, liver, jaundice, urine and tears are reddish brown to orange.

Handling

Often treated by gastrointestinal, using activated carbon, using diuretic. It is better to call the doctor or take the patient to the nearest medical facility for timely support.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Rifampicin medicine , you may experience unwanted effects (ADR).

This drug can make urine, feces and tears red.

Gastrointestinal disorders mild, itching, rash.

rarely

Fatigue, headache, increased transaminase, jaundice.

rarely

Ophthalmology, leukopenia, anemia hemolysis. Notify the doctor the unwanted effects when using the drug.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Rifampicin medicine contraindicated in the following cases:

Hypersensitivity to the rifamycin and any ingredients of the drug.

Porphyrin metabolic disorders.

Severe liver failure (if combined with inh).

Precautions when using

Caution when used for pregnant women, babies.

During the treatment period, the blood formula and liver function must be conducted.

The ability to drive and operate machinery

The drug can cause drowsiness, dizziness. So be careful when using the drug for this object, so check the feeling of drowsiness before work.

Pregnancy

Animal experiments show that drugs that cause bone defects. Using drugs in the last 3 months of pregnancy can cause bleeding for mothers and children. Therefore, careful consideration between benefits and risks may occur before taking the drug. Consult your doctor when taking the drug for this object.

Breastfeeding period

The drug is excreted through breast milk. However, almost no harm to children. Be careful when using the drug for this object.

Medicinal interaction

Rifampicin in combination with Isoniazid (Inh) and Pyrazinamid will increase the toxicity of the liver.

Rifampicin causes cytochrom P450 enzyme induction, increasing the metabolism of drugs: contraceptive drugs, anticoagulants, digitoxin , ketoconazol, erythromycin, clarithromycin, diazepam , beta blockers, calcium blockers, etc. dose adjustment.

Some drugs when used with rifampicin will reduce Rifampicin absorption: acid resistance, bentonite, clofazimin, ... overcome by separate drinks 8 - 12 hours apart.

To avoid interactions between drugs, notify the doctor or pharmacist about the drugs being used.

Storage

In a dry place, the temperature does not exceed 30 ° C, avoiding light.

Other drugs

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