Risenate Davipharm treatments for osteoporosis in menopausal women (1 blister x 4 tablets)

Dosage form Box of 1 blister x 4 tablets
Specifications Alendronate sodium

Ingredient

Composition information	Content
Alendronate sodium	70mg

Uses

indications

Risenate drugs are indicated in the following cases:

Treatment of osteoporosis in menopausal women. Alendronat accumulates selectively at the active bone pepper position, inhibits the operation of the cell cancel.

Alendronat treatment can significantly increase the volume of bone in the spine, femur and transfer. However, after 1-2 years of treatment, if the alendronat is stopped, it does not maintain an increase in bone mass. This proves to be constantly treated daily to maintain the healing effect.

Dynamic pharmacokinetics

Absorption: Compared to an intravenous, medium -sized oral abuse standard in women, 0.7% with doses in the range of 5 - 40 mg, oral after 1 fast and 2 hours before a standard breakfast.

Distribution: Alendronate is transiently distributed in soft tissue, then redistributed to the bone or exit through the urine. Linking with plasma proteins is about 78%.

Metabolism and elimination: After the only dose of 10 mg, the renal clearance is 71 ml/min. Half -life of the drug is over 10 years, probably due to the release of Alendronat from the bone.

Before taking Risenate Davipharm treatments for osteoporosis in menopausal women (1 blister x 4 tablets)

How to use

Risenate drugs for oral use.

Swallow the pills with 180 - 240 ml of water (no mineral water or other drinks) before eating at least 30 minutes. The patient avoids it in 30 minutes after taking alendronat to make the drug easily and reduce the potential of esophageal irritation.

Do not take Alendronat at bedtime or before waking up during the day.

Dosage

recommended dose: 70 mg/ week.

Note:

Unnecessarily adjust the dose for the elderly, people with liver failure, mild renal failure people. There is no experience used for people with severe renal failure.

The dose above is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Use milk and antacid agents to bind alendronat.

Due to the risk of esophageal irritation, not vomiting and patients still have to sit upright.

What to do when you forget a dose? Then return to your usual weekly schedule on the selected dosage date. Do not take 2 doses in a day.

Side Effects

When using Risenate, you may experience unwanted effects (ADR).

The reactions are usually mild, generally no need to stop the drug.

Common, ADR> 1/100

Neurological: headache.

digestion: flatulence, acid reflux, esophageal ulcer, bloating.

Uncommon, 1/1000

Skin: rash.

digestive: gastritis.

Instructions on how to handle ADR

Notify the physician the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Risenate drugs contraindicated in the following cases:

esophageal deformities.

Inability to stand or sit upright for at least 30 minutes.

Too hypersensitivity to any ingredients in the preparation.

Reducing blood calcium.

Be cautious when using

Alendronate irritates the gastrointestinal mucosa, need to be cautious when using Alendronat for people with pathologies that are active in the digestive tract (for example, difficulty swallowing, esophageal disease, gastritis, duodenitis or ulcers).

Must treat blood calcium loss, vitamin D deficiency before starting with Alendronat treatment.

The ability to drive and operate machinery

There is no data that proves drugs that affect the ability to drive and operate machinery. No research on the impact of the drug on the ability to drive and operate machinery.

Pregnancy

Do not use alendronat for people during pregnancy.

Breastfeeding period

It is unknown whether alendronat will be exported to breast milk or not. Should be cautious when taking medicine for breastfeeding women.

Drug interaction

estrogen: has not determined safety and effectiveness when used simultaneously, so it should not be combined.

Calcium supplements and anti -acid drugs: reduce alendronat absorption. These drugs should be taken after taking alendronats, especially half an hour.

Non -steroid anti -inflammatory drugs: Increases the rate of side effects on the gastrointestinal tract when using alendronate at a dose higher than 10 mg/ day. Should be cautious when combined.

Storage

In a dry place, avoid light, the temperature does not exceed 30 ° C.

Other drugs

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