Ritsu Medisun treated primary and secondary carnitin deficiency (20 pipes x 10ml)

Dosage form 20 tube box
Specifications Levocarnitin

Ingredient

Thành phần cho 10ml

Composition information	Content
Levocarnitin	1000mg

Uses

Indications

Ritsu oral drugs are indicated in cases of primary and secondary carnitin deficiency in adults and children over the age of 12.

Pharmacology

Pharmacological group: digestion and metabolism

ATC code: A16AA1

Levocarnitin is a natural active ingredient, essential for energy metabolism in mammals, levocamitin has the effect of transporting long fatty acids into the mitochondria, thereby providing substrates for oxidation and energy production. Fatty acids are used as a substrate in all tissues, except for brain graves. In skeletal and heart muscle, fatty acids are the main substrate in energy production.

Dynamic pharmacokinetics

Pharmacokinetic information of levocarnitin used on adults and forms used on young children are no different.

Absorption: The drug concentration in plasma is achieved after 3.3 - 3.4 hours oral medication.

Distribution: The drug is not linked to protein and plasma albumin.

Metabolism: The drug is metabolized into Tmao and γ-butyrobetain forms in the digestive tract under the effects of intestinal bacteria. The sale time of the drug is about 17.4 hours.

Elimination: The drug excreted about 9% in the urine in the form of unprocessed. About 58 - 65% of the drug is metabolized through feces and urine in both metabolized or unprocessed forms.

The effects and safety of levocarnitin orally have not been reported on patients with renal impairment. The use of oral levocarnitin at high doses in patients with severe renal function or end-stage renal disease (ESRD) can lead to the accumulation of toxic metabolites such as Trimethylamin (TMA) and Trimethylamin-N-OXID (TMAO), because these transformers are often excreted in urine.

There is no special data when comparing the effect of the drug between the elderly and other patients, but based on existing data, unwanted effects or other problems may be encountered on the elderly are not different from young adults.

Be cautious when using drugs in patients with liver disease because there is no complete research data on this object.

Before taking Ritsu Medisun treated primary and secondary carnitin deficiency (20 pipes x 10ml)

How to use

oral Ritsu drugs. Can drink directly or dilute in water/juice.

Dosage

Adults and children:

Need to monitor the concentration of free carnitin and associated with acyl in the blood and urine of the patient during treatment.

For patients with congenital metabolic disorders:

Dosage depends on the metabolic disorders of each patient and clinical manifestations, but it can follow the following general instructions:

The dose of 200 mg/kg/day, divided into 2-4 times/day is recommended for chronic heads. In case the clinical manifestations are not improved, it may increase to a higher dosage in a short time. Whether 400 mg/kg/day may be necessary in cases of acute and acute compensation disorders, or the patient may turn to intravenously.

For patients with hemolysis - maintenance treatment:

If the patient has been levocarnitine intravenously and is effective in the initial treatment, the maintenance dose may be 1 g/day as oral. On the day of hemolysis, use the drug at the end of the session.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Ritsu drugs often experience unwanted effects (ADR) such as:

Common, 1/10> 1/100

Cardiovascular: High blood pressure.

Cardiovascular: tachycardia 1/1000

epilepsy.

Instructions on how to handle unwanted effects:

In case of patients who have side effects on the digestive system or fatigue: No need to stop the drug because these symptoms will disappear in a short time.

In case of patients with body odor: The patient can be reduced.

Other cases: Stop taking medication and treat symptoms for patients if necessary.

Notify the physician the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Ritsu drugs contraindicated in the following cases:

allergies to Carnitin or any ingredients of the drug.

Be cautious when using

Patients with kidney disease or kidney failure or patients who are hemolysis.

Patients with diabetes and are taking insulin or any drug to treat diabetes.

Patients who are using anticoagulants (such as wafarin).

Products contain propylparaben and methylparaben, so pay attention to the allergic reaction may be encountered when using this product.

The effect of the drug on the ability to drive and operate machinery

The drug does not affect the driver or the person operating machinery.

Using drugs for women during pregnancy and lactation

levocarnitin does not cause toxicity in the fetus or teratogenic in test animals.

However, there is no data on the safety of the drug during pregnancy in humans. Therefore, it is only recommended to use drugs during pregnancy.

There is no levocarnitin data excreted through breast milk. Research on cows shows that levocarnitin content increases in cow's milk after being injected. Therefore, it is necessary to consider the risk of levocarnitin on babies with the benefits of adding levocarnitin to the mother.

Interactive drug

The drug may increase the effects of anticoagulants (such as warfarin).

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

Other drugs

Disclaimer

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