Rovas 3m DHG medicine for respiratory infections, skin (2 blisters x 5 tablets)

Dosage form Box of 2 blisters x 5 tablets
Specifications Spiramycin

Ingredient

Composition information	Content
Spiramycin	3,000,000iu

Uses

indications

Rovas drugs are indicated in the following cases:

Spiramycin is considered the second choice to treat cases of respiratory, skin and genital infections due to sensitive bacteria that are sensitive to drugs.

Preventive treatment for meningitis caused by meningococcus, when contraindicated with rifampicin.

Preventive toxoplasmab infection during pregnancy.

Pharmacology

Spiramycin is an antibiotic group macrolid.

In serum concentrations, the drug has a bactericidal effect, but when it reaches the concentration in the tissue that can kill bacteria. The mechanism of the effect of Spiramycin is the effect on the subunit of 50S of bacterial ribosom and preventing protein synthetic bacteria. Spiramycin has a resistant effect of gram -positive strains, coccus strains such as staphylococcus, pneumococcus, meningococcus ...

Pharmacokinetics

absorption

Spiramycin is not completely absorbed in the digestive tract. Oral drugs are absorbed about 20-50% of the dose of use. The peak concentration of plasma is achieved within 2-4 hours after drinking. The concentration of peaks in the blood after the single dose can be maintained for 4 to 6 hours. Drinking Spiramycin when there is food in the stomach greatly reduces the bioavailability of the drug. Food reduces about 70% of the maximum concentration of the drug in the serum and makes the peak time from 2 hours.

Distribution

Spiramycin is widely distributed throughout the body. The drug reaches high concentrations in the lungs, tonsils, bronchial and sinuses. Spiramycin is less penetrated into the cerebrospinal fluid.

Elimination

The average selling time is 5 - 8 hours. The drug is excreted mainly in bile. After 36 hours, only about 2% of the total dose is found in the urine.

Before taking Rovas 3m DHG medicine for respiratory infections, skin (2 blisters x 5 tablets)

How to use

Food in the stomach reduces the bioavailability of Spiramycin, so it is necessary to give the medication before meals for at least 2 hours or after a 3 -hour meal.

Patients using Spiramycin must follow the end of the treatment.

Dosage

Dosage treatment

Adults and children over 12 years: Take 3,000,000 IU, 3 times in 24 hours (1 tablet x 3 times/day).

Preventive treatment for meningitis caused by meningococcus strains

Adults and children over 12 years old: Take 3,000,000 IU, every 12 hours (1 tablet 2 times/day).

Preventive prophylaxis of congenital toxoplasma during pregnancy

Take 9,000,000 IU/day (3 capsules/day), divided into several times, drink for 3 weeks, every 2 weeks for the reminders.

Used in combination or alternating with Pyrimethamine/Sulfonamid treatment regimen can achieve better results.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? In case of an overdose of the prescribed overdose should notify the doctor immediately.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Rovas, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive: Nausea, vomiting, diarrhea, indigestion (when used oral).

Uncommon, 1/1000

Body: fatigue, nosebleeds, sweating, chest pressing.

temporary, disturbing, staggering, pain, muscle and joint, burning sensation, redness (when intravenously). digestive: acute colitis.

Skin: Ban Da, Ban Ban, Rural.

Rare, ADR

Anaphylactic reactions, superinfection due to long -term use of spiramycin oral medicine.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Rovas drugs contraindicated in the following cases:

People with a history of hypersensitivity to Spiramycin and erythromycin.

Be cautious when used

Precautions when used for patients with liver dysfunction because the drug can be toxic to the liver.

The ability to drive and operate machinery

rarely affects the ability to drive and operate machinery.

pregnancy

spiramycin passes through the placenta, but the concentration of drugs in the fetal blood is lower than the mother's blood. Spiramycin does not cause complications when used for pregnant women.

The period of breastfeeding

Spiramycin is excreted through breast milk with high concentrations. Should stop breastfeeding while taking the drug.

Medicinal interaction

use Spiramycin simultaneously with oral contraceptive medicine to prevent conceiving effects.

Storage

In a dry place, the temperature does not exceed 30 ° C, avoiding light.

Other drugs

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