Roxithromycin 150mg Imexpharm treatments for bacterial infections, diphtheria, and pertussis (2 blisters x 10 tablets)

Dosage form Box of 2 blisters x 10 tablets
Specifications Roxithromycin

Ingredient

Composition information	Content
Roxithromycin	150mg

Uses

indications

PMS - Roxithromycin 150mg is indicated in the following cases:

Treatment of bacterial infections caused by Mycoplasma Pneumoniae and Legionella.

Roxithromycin is an antibiotic macrolid, has a broad spectrum with Gram -positive bacteria and a few Gram -negative bacteria. Clinically Roxithromycin often works for Streptococcus Pyogenes, S. Viridans, S. Pneumoniae, Staphylococcus Aureus sensitive Methicillin, Bordetella Pertussis, Branhamella CatVrhalis, Coryenebacterium Diphtheriae, MyCoplasma Pneumoniae Chlamydia Trachomatis, Legionella Pneumophila, Helicobacter Pylori and Borrelia Burgdorferi.

Roxithromycin has antibacterial spectrum like benzyl penicilin.

Dynamic pharmacokinetics

Absorption: After taken, the drug absorbs with bioavailability about 50%. The peak concentration of plasma is about 6 - 8 mcg/ml reached about 2 hours after taking a single dose of 150 mg. The ability to absorb drugs is reduced when taken after meals.

Distribution, metabolism: Roxithromycin is widely distributed into the body's tissue and fluid, and diffuses into breast milk in small amounts. The drug is linked to plasma protein about 87 - 96%. A small amount of Roxithromycin metabolized in the liver.

Elimination: constant form and metabolites of Roxithromycin are excreted mainly in feces, about 7-10% in urine and 15% through the lungs. The sale time is about 8 - 13 hours, lasting longer in patients with liver or kidney failure or in children. The drug is not excluded by peritoneal fertilizer.

Before taking Roxithromycin 150mg Imexpharm treatments for bacterial infections, diphtheria, and pertussis (2 blisters x 10 tablets)

How to use

Take oral use.

Dosage

for adults

Daily dose: 150 mg, taken 2 times/day before meals.

for children

Dosage is often used for babies: 5 - 8 mg/kg/day, divided into 2 times.

Do not use the form of tablets for children under 4 years old.

Other objects

Severe liver failure: The dose must be reduced by half of the normal dose.

Renal failure: No need to change the usual dose.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when using overdose? Stomach lavage. Treatment of symptoms and support.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not use double the prescribed dose.

Side Effects

When using PMS - Roxithromycin 150mg , you may experience unwanted effects (ADR).

Unknown frequency

Digestive: Nausea, vomiting, epigastric pain, diarrhea .

Instructions on how to handle ADR

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

PMS - Roxithromycin 150mg contraindicated in the following cases:

People with a history of hypersensitivity to antibiotics of macrolid groups.

Caution when using

is especially cautious for people with severe liver failure.

The ability to drive and operate machinery

There is no data recorded about the use of Roxithromycin for drivers or operating machines but recommend users because the drug has an unwanted effect is dizziness, dizziness, headache.

Pregnancy

only used for pregnant women when really necessary, although there is no document that mentions Roxithromycin causing birth defects.

breastfeeding period

Roxithromycin excreted milk with very low concentrations.

Drug interaction

combine Roxithromycin with one of the following drugs: Astemizol, Terfenadin, Cisaprid has the potential to cause severe heart disorders. Therefore, do not combine these drugs for treatment.

There is no significant interaction with warfarin, carbamazepin , cyclosporin and oral contraceptives.

Increases theoophylin or ciclosporin levels in plasma, but does not need to change the usual dose.

may increase the concentration of non -linked disoperamid concentration in serum.

Do not coordinate with bromocriptin because Roxithromycin increases the concentration of this drug in plasma.

Storage

less than 300C, avoid moisture and light.

Other drugs

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