Salzol Windlas Biotech oral solution for asthma, asthma, bronchospasm (100ml)

Dosage form Box X 100ml
Specifications Salbutamol

Ingredient

Thành phần cho 5ml

Composition information	Content
Salbutamol	2mg

Uses

Indications

Salzol oral solution is indicated in adults, adolescents and children from 2 to 12 years old.

Salbutamol belongs to the selected co-drug group on the Adrenergic Beta-2 receptor, which is indicated to relax the bronchial and uterus muscles. Salbutamol oral solution can be indicated in the following cases:

Asthma, asthma.

Pharmacology

Pharmacological Group: Beta -2 Adrenergic receptor selection

ATC code: R03AC02

Salbutamol is a selective of Beta -2 adrenergic receptor receptor, which reduces the symptoms of bronchospasm due to chronic or acute asthma, bronchitis or other obstructive pulmonary disease. Due to the acting with the beta-2 receptor, Salbutamol relaxes the bronchi smooth muscle, uterus and blood supply vessels to the skeletal muscle, in general, Salbutamol stimulates the heart less than the isoproterenol is a substance that has a strong effect on all beta receptors.

Dynamic pharmacokinetics

Salbutamol intravenously has a half-life of 4 to 6 hours and is mostly excreted through the kidneys and is mostly in the form of inactive metabolites 4'-O sulphate (phenolic sulphate) that this metabolism is also excreted mainly through urine. A small part is excreted in the stool. After intravenous, drinking or spraying, most of the salbutamol is excreted for 72 hours. Salbutamol binds with plasma proteins about 10%. After drinking, Salbutamol is absorbed from the gastrointestinal tract and initially converted into Phenolic Sulphat. The whole drug is unchanged and the combination is excreted mainly through the urine. Birth of Salbutamol orally about 50%.

Before taking Salzol Windlas Biotech oral solution for asthma, asthma, bronchospasm (100ml)

How to use

oral solution Salzol oral solution.

Dosage

Adults: The minimum starting dose is 2 mg/time in the form of 5ml of solution, 3 times/day. The usual dose is 4mg (10ml of the solution, 3-4 times/day. It can be increased to 8mg (20ml of solution/time, 3-4 times/day if the bronchodilator effect is not achieved.

Elderly or patients sensitive to this drug or other similar drugs: starting the dose of 2 mg/time, 3-4 times/day.

Children 2 - 6 years old: 1mg (2.5ml of solution)/time, 3 times/day. The dose can be increased to 2mg (5ml of solution), 3-4 times/day.

Children 6 - 12 years old: 2mg (5ml of solution)/time, 3 times/day, can increase to 4 times/day.

Children over 12 years: 2mg (5ml of solution/time, 3 times/day. It can be increased to 4mg (10ml of solution), 3-4 times/day.

Children under 2 years of age: Contraindications. Salbutamol oral solution is well tolerated in children, so if necessary the doses may increase to the maximum dose. For doses lower than the concentration of the solution can be diluted with pure water.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? Hypotension can occur when the salbutamol overdose. Plasma potassium concentration should be monitored.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

Side effects are listed by organ systems and frequency. The frequency is very popular (≥1/10), common (≥ 1/100 and

Immune system disorders:

Very rare: Hypersensitivity reactions including angioedema, urticaria, bronchospasm, hypotension and depression.

Rare: Hematopathy. Can cause severe hypotension when treated with beta -owners.

Nervous system disorders:

Very popular: Run.

Common: headache.

Common: tachycardia, chest drum.

Rare: Peripheral vasodilation.

Common: muscle cramps. Report from data after circulation of drugs with unknown frequency.

Instructions on how to handle ADR:

Notify the physician with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Oral solution of contraindications in the following cases:

allergies (hypersensitivity) with salbutamol or any ingredients of Salbutamol tablets.

Be cautious when using

Patients with rare genetic problems are galactose intolerance, lactase deficiency or glucose-galactose abutments should not be used. Bronchodilators are not only the only treatment in patients with severe or unstable asthma. Increasing the use of bronchodilators, especially inhaled, has a short effect of beta-2 fortunes to reduce symptoms to control asthma. If the patient feels that the treatment with a short -acting effect to treat bronchiectasis is increasingly reduced or they have to use more than before to work, they need to help medical health immediately. Salbutamol causes peripheral vessels, so it can cause reflective tachycardia and increase cardiac supply.

Hyperthyroidism: Salbutamol should be used cautiously in patients with pain due to thyroid poisoning after being carefully evaluated for benefits and risks of treatment. The continuous monitoring of potassium concentrations in severe asthma patients is essential, serious hypokalemia may be the result of the use of beta-2 agonetic therapy. Using Salbutamol with other B-adrenergic receptors can cause changes that can recover to metabolism such as hyperglycemia.

diabetes: Using beta antacids can increase blood sugar. Therefore, blood sugar and lactate levels need to be monitored in diabetics and diabetes treatment regimens should be adjusted to suit diabetics during the use of spasms. Diabetes may not be able to adjust the increasing sugar in the sample and the development of ceton acid infections has been reported. The combination of corticosteroid medicine may increase this effect. Cardiovascular effects may appear with sympathetic drugs, including salbutamol. There are a few data after circulation of the drug and on references on myocardial ischemia related to beta agonized substances.

Respiratory indications: Patients with serious heart disease (eg, ischemic heart disease, arrhythmia or severe heart failure) that use Salbutamol should be warned for medical assistance if they feel chest pain or symptoms of heart disease deteriorating. Pay attention to the assessment of symptoms such as shortness of breath and chest pain as they can be a sign related to respiratory or cardiovascular disease.

Use 1 month after opening the lid.

The effect of the drug on the ability to drive and operate machinery

has not seen the drug that affects the ability to drive or operate machinery.

Using drugs for women during pregnancy and lactation

Pregnant women: Salbutamol is only used during pregnancy if the doctor has been carefully considered by the doctor.

breastfeeding women: Because salbutamol can be secreted into breastfeeding, should be cautious when used. It is unknown whether Salbutamol is harmful in babies, so the use of drugs should be considered between the interests of the mother compared to the risk of babies.

Interactive drug

The effect of salbutamol may be changed by guanethidin, reserpin, methyldopa, triple antidepressants and monoamine inhibitors.

The risk of hypokalemia may increase if theoophylin or high doses of corticosteroids with high doses of salbutamol.

Halogen anesthetics: Due to the hypotension effect, it can increase the stubbornness of the uterus with the risk of bleeding, in addition, serious ventricular arrhythmia due to an increase in cardiovascular reaction has been reported when coordinated with halogen anesthesia. Treatment should be stopped, at any time, and at least 6 hours before anesthesia according to the schedule using halogen anesthesia.

Diabetes treatment: The use of beta -owners is associated with an increase in blood sugar, and may impair the effect of diabetes treatment. Therefore, diabetes treatment may need to be adjusted.

Agent in reducing potassium: Due to the impact of hematuria of the beta owner, simultaneous use with substances that reduce blood potassium should be understood to avoid increasing the risk of reducing blood potassium, such as diuretics, digoxin, methylxanthine and corticosteroids, and the use needs to be careful to be careful about the benefits and risks that are related to the risk of rise to the risk of rise to the risk. Consequences of hypokalemia.

Storage

Store in a cool dry place, temperatures below 30 ° C.

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