Sanlein eye drops 0.3% Santen supports the treatment of corneal cone disorders (5ml)

Dosage form Bottle
Specifications Pure Sodium Hyaluronate

Ingredient

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Composition informationContent
Pure Sodium Hyaluronate15mg

Uses

Indications

0.3% Sanlein drug is prescribed in case of use in cases of conjugal disorders - cornea due to the following diseases:

  • Inner diseases such as Sjogren’s syndrome, Stevens-Johnson syndrome and dry eye syndrome.

    Sodium hyaluronate is attached to fibronectin and promotes corneal adhesion and relaxation. Sodium Hyaluronate also has very good water retention properties because each sodium Hyaluronate molecule can hold many water molecules.

    Promotes the healing of corneal damage

    When the small solution of sodium hyaluronate eye is 0.1% - 0.5% in the lesions of the rabbit, including the cornea and corneal epithelium that has been peeled off the bottom of the bottom, the area is significantly reduced compared to when using the small eye solution (plantbo) from 24 hours onwards after dissection.

    Promoting corneal elongation

    Sodium Hyaluronate significantly promotes the long corneal epithelium relaxation compared to the evidence group (only cultured medium) in the pieces of cultured cornea.

    Water retention characteristics

    When the sodium hyaluronate solution is small - 1.0% in agar plugs, the decrease in the mass of the jelly buttons due to evaporated water has been prevented in a way depends on the concentration.

    pharmacokinetic pharmacokinetics

    Serum concentration

    Serum concentration of hyaluronic acid was measured before the drug as well as on the day of treatment: day 3, 9 (the last day of taking the drug) and the 10th at 6 healthy male volunteers.

    0.1% Sodium Hyaluronate eye solution (1st) and 0.5% (September 2) is small at 1 drop of 1 drop, 5 times/day (1-2) and 1 drop, 13 times daily (3 - 9) on one eye of the objects. All serum concentrations are measured before, during and after treatment are lower than the quantitative limit (10 µg/ml).

    Internal distribution

    After using the single dose 50 µl of small sodium Hyaluronate eye solution 14C 0.1% in rabbits with normal cornea, radioactive is only detected in the outside of the eye. In particular, the high radioactive level in the conjunctiva wall and was discovered at least 8 hours after use. In contrast, the low radioactive level in the cornea and is only detected in 0.5 hours after use.

    After being used on the spot 50 µl of small sodium Hyaluronat 14C 0.1% sodium eye solution in the rabbit with damaged cornea, high concentration radioactive has been detected in the cornea and in the aquatic fluid immediately 1 hour after use.

    • Before taking Sanlein eye drops 0.3% Santen supports the treatment of corneal cone disorders (5ml)

    How to use

    0.3% Sanlein medicine is used to eye eye.

    Dosage

    Normally, put in the eyes 1 drops, 5-6 times/day. The dosage can be adjusted according to the patient's symptoms.

    Normally, choosing the drug with a concentration of 0.1% and when the effectiveness of the drug is not fully achieved due to severe symptoms ... it is possible to use the drug with a concentration of 0.3%.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

    What to do when overdose?

    Unknown.

    In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

    What to do when forgetting a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

    Side Effects

    When using 0.3%Sanlein, you may experience unwanted effects (ADR).

    Unwanted effects for this drug are reported at 74 out of 4,208 patients assessed before the drug is approved and during investigation of drug use in Japan (1.76%). The unwanted effect is eyelid itching in 19 patients (0.45%), eye irritation in 15 patients (0.36%), conjunctival congestion in 10 patients (0.24), lash inflammation in 7 patients (0.17%) ... (at the end of the re -evaluation period in Japan).

    If observing the following unwanted effects, it is advisable to apply appropriate measures such as stopping the drug.

    Ratio (5%> ADR and ADR ≥ 0.1%)

  • Hypersensitivity: eyelash infection, eyelid dermatitis
  • Eyes: eye rust, eye pain.

    Instructions on how to handle ADR

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    • Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    0.3% Sanlein Sanlein drug in the following cases:

  • Patients with a history of hypersensitivity to any component of the drug.

    • Precautions when using

    Read the instructions carefully before use. If you need more information, please consult your doctor.

    This drug is only used by a doctor.

    Sugar used: Only eye small.

    To be out of reach of children.

    Do not touch the head of the vial directly into the eye to avoid pesticides.

    Do not use this medication while wearing soft contact lenses.

    When using more than 1 eye drops, must be at least 5 minutes apart.

    The ability to drive and operate machinery

    unknown.

    pregnancy

    unknown.

    Breastfeeding period

    unknown.

    Drug interaction

    unknown.

    Storage

    Store under 30 ° C in closed packaging.

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    Disclaimer

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    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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