Sara 120mg/5ml nakorn Patana strawberry fever, pain relief for children (60ml)

Dosage form Chaos
Specifications Bottle x 60ml
Ingredient Paracetamol

Ingredient

Composition information	Content
Paracetamol	120mg

Uses

indications

SARA (strawberry incense) used to treat antipyretic, pain relief for children and infants.

Pharmacokinus

Pain relief: The mechanism has not been fully determined. Paracetamol can act by inhibiting prostaglandin synthesis in the central nervous system and at a lower level, through peripheral effects by preventing pulse transmission of pain. The peripheral impact may also be due to prostaglandin synthesis, synthesis inhibitors or inhibition of impacts of sensitive substances with painful receptors to cause mechanical or chemical irritation.

A reduction of fever: Paracetamol acts on the hypothalamic thermostat center, causing peripheral vasodilation, sweating and escaping heat.

The main effect may be related to the ability to inhibit the synthesis of prostaglandin.

Dynamic pharmacokinetics

absorption

Paracetamol is absorbed quickly and almost completely through the digestive tract.

Distribution

In normal analgesic dose, plasma sum concentration from 5 - 20 µg/mg.

Paracetamol is mainly metabolized and eliminated through urine in the form of non -active combination with glucuronic acid and sulfate (94%).

2 - 4% of unchanged excretion pills. The average selling time is about 1-3 hours, prolonged in infants and cirrhosis patients.

Before taking Sara 120mg/5ml nakorn Patana strawberry fever, pain relief for children (60ml)

How to use

Sara (strawberry incense) Used orally.

Dosage

Common dose: Take 4 - 6 hours when necessary but not exceeding 5 times/day.

Children 4 months - 1 year: 1/2 teaspoon (equivalent to 2.5 ml)/time.

Children 1-2 years: 1 teaspoon (equivalent to 5 ml)/time. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Symptoms of overdose: Nausea, vomiting, abdominal pain, purple blue, mucosa, nails. The liver necrosis depends on the dose is the most serious toxic effect due to overdose. Liver damage becomes clearly within 2-4 days after taking the poison.

Handling: gastrointestinal, drinking or intravenous n-acetylcysteine intravenously to detoxify paracetamol. Without n-acetylcystein, methionine, activated carbon and/ or salt bleach.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

Unwanted effects when using Sara that you may encounter.

Common, ADR> 1/100

No report.

DA: rash.

digestive: nausea, vomiting. Hematology: Disorders of hematopoietic systems (neutrophils decreased, all bloody, leukopenia), anemia. kidney: Kidney disease, kidney toxicity.

rare, ADR

Body: Hypersensitivity reaction.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Sensitive to paracetamol or any ingredient of the drug.

History of many times anemia or heart, lung, kidney or liver disease.

Lack of Glucose 6 Phosphate Dehydrogenase (G6PD).

Caution when using

paracetamol is relatively non -toxic to the dose of treatment.

However, do not use more than 5 days. If the pain is severe or recur, the fever is high or the fever is constantly, the disease is serious and the doctor needs to be diagnosed by the doctor. If the pain persists for more than 5 days, swollen redness or rheumatism in children

If there is a sensitive reaction, the drug must be stopped.

The drug contains sorbitol excipients, so it is necessary to be careful when indicated for patients to not tolerate some types of sugar.

The incidence of serious side effects on the skin is not high but serious, even life-threatening including Steven-Jonhson syndrome (SJS), toxic skin necrosis syndrome (Ten) or Lyell syndrome, acute overseas pustules syndrome (AGEP).

Symptoms of the above syndrome are described as follows:

Steven-Jonhson syndrome (SJS): is an allergy of puffiness, bullous puffiness around natural cavities: eyes, nose, mouth, ears, genitals and anus, which can be accompanied by high fever, pneumonia, liver dysfunction. Diagnosis of Steven-Jonhson syndrome (SJS) when at least 2 natural cavities are damaged. Eye mucosa damage (keratitis, pus conjunctivitis, corneal ulcer); Damage to the gastrointestinal tract (stomatitis, mouth mucosa, pharynx, throat, esophagus, stomach, intestines) and damage to the mucosa of the genital tract, urinary tract. Damage often appears in folds such as armpits, groin and face, then can spread the whole body. Systemic symptoms are often fever, neutral leukemia test increased.

When detecting signs of hypersensitivity reactions as above, the patient must stop using the drug immediately. Those who have been reacted on the skin seriously due to paracetamol must not be used again and when they come to medical examination and treatment, they need to notify the medical staff on this issue.

The ability to drive and operate machinery

does not affect the ability to drive and operate machinery.

Pregnancy

can specify paracetamol for pregnant women according to the doctor's instructions.

The period of breastfeeding

paracetamol is less excreted on breast milk, so it can be appointed for women who are breastfeeding.

Drug interaction

Long -term oral high doses Paracetamol increases the anticoagulant effect of COUMARIN and derivatives.

Out and prolonged during Paracetamol treatment may increase the risk of liver toxicity.

Concentrated use of anti -convulsions (phenytoin, barbiturat, carbamazepine) causes liver enzyme induction, which can increase the toxicity of the liver.

Storage

Store at temperatures below 30 ° C, avoiding light.

Nakorn Patana pregnancy limited liability company has achieved a good standard of practicing drug production as recommended by the World Health Organization (GMP-WHO) for β-Lactam antibiotic lines, including: tablets, tablets, drinks, creams, ointments, external broth and inhales. In addition, the company also meets the standards of GLP, GSP, GDP.

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